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Signalling sphingomyelinases: which, where, how and why?
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scholarly article
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stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
review article
1 reference
stated in
Europe PubMed Central
title
Signalling sphingomyelinases: which, where, how and why?
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
author name string
T Levade
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
J P Jaffrézou
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
language of work or name
English
0 references
publication date
1 April 1999
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
volume
1438
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
page(s)
1-17
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
issue
1
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
cites work
Ceramide signalling and the immune response
1 reference
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Crossref
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https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functions of ceramide in coordinating cellular responses to stress
1 reference
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reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
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inferred from DOI database lookup
Sphingolipid metabolism and cell growth regulation.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction through lipid second messengers
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
The role of sphingolipids in the process of signal transduction
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Modulation of cell signalling by ceramides.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of ceramide production and apoptosis
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Signal transduction of stress via ceramide
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Functions of sphingolipids and sphingolipid breakdown products in cellular regulation
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingomyelin and derivatives as cellular signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide in apoptosis--does it really matter?
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide synthase mediates daunorubicin-induced apoptosis: an alternative mechanism for generating death signals
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
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7 January 2021
based on heuristic
inferred from DOI database lookup
Daunorubicin activates NFkappaB and induces kappaB-dependent gene expression in HL-60 promyelocytic and Jurkat T lymphoma cells
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of de novo ceramide biosynthesis in tumor necrosis factor-alpha/cycloheximide-induced cerebral endothelial cell death.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Positive feedback control of neutral sphingomyelinase activity by ceramide.
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lysosomal localization of sphingomyelinase in rat liver
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Magnesium-dependent sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Existence of Mg2+-dependent, neutral sphingomyelinase in nuclei of rat ascites hepatoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Degradation of fluorescent and radiolabelled sphingomyelins in intact cells by a non-lysosomal pathway
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neutral sphingomyelinase: localization in rat liver nuclei and involvement in regeneration/proliferation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chromatin neutral sphingomyelinase and its role in hepatic regeneration
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The presence of sphingomyelin- and ceramide-cleaving enzymes in the small intestinal tract
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of an alkaline sphingomyelinase activity in human bile
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Zn2+-stimulated sphingomyelinase is secreted by many cell types and is a product of the acid sphingomyelinase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingomyelinases in human, bovine and porcine seminal plasma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick diseae
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An update of the enzymology and regulation of sphingomyelin metabolism
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Intracellular transport and metabolism of sphingomyelin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Localization of neutral, magnesium-stimulated sphingomyelinase in plasma membrane of cultured neuroblastoma cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence that neutral spingomyelinase of cultured murine neuroblastoma cells is oriented externally on the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF activates NF-kappa B by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor (TNF)-alpha activates c-raf-1 kinase via the p55 TNF receptor engaging neutral sphingomyelinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Oxidized low density lipoprotein induces apoptosis in cultured human umbilical vein endothelial cells by common and unique mechanisms
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role of an acidic compartment in tumor-necrosis-factor-alpha-induced production of ceramide, activation of caspase-3 and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingomyelin synthase, a potential regulator of intracellular levels of ceramide and diacylglycerol during SV40 transformation. Does sphingomyelin synthase account for the putative phosphatidylcholine-specific phospholipase C?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Potential role for ceramide in mitogen-activated protein kinase activation and proliferation of vascular smooth muscle cells induced by oxidized low density lipoprotein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloned mammalian neutral sphingomyelinase: functions in sphingolipid signaling?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Purification and characterization of a membrane bound neutral pH optimum magnesium-dependent and phosphatidylserine-stimulated sphingomyelinase from rat brain.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Compartmentalized production of ceramide at the cell surface
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Low temperatures and hypertonicity do not block cytokine-induced stimulation of the sphingomyelin pathway but inhibit nuclear factor-kappa B activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingomyelin breakdown and cell fate
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Induction of stress-activated protein kinases/c-Jun N-terminal kinases by the p55 tumour necrosis factor receptor does not require sphingomyelinases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TNF receptor death domain-associated proteins TRADD and FADD signal activation of acid sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective involvement of ceramide in cytokine-induced apoptosis. Ceramide inhibits phorbol ester activation of nuclear factor kappaB.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of brain G-protein go by Alzheimer's disease gene presenilin-1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor cell resistance to apoptosis due to a defect in the activation of sphingomyelinase and the 24 kDa apoptotic protease (AP24).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Alteration of the sphingomyelin/ceramide pathway is associated with resistance of human breast carcinoma MCF7 cells to tumor necrosis factor-alpha-mediated cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Anti-immunoglobulin-induced apoptosis in WEHI 231 cells involves the slow formation of ceramide from sphingomyelin and is blocked by bcl-XL.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lack of ceramide generation in TF-1 human myeloid leukemic cells resistant to ionizing radiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence against involvement of the acid lysosomal sphingomyelinase in the tumor-necrosis-factor- and interleukin-1-induced sphingomyelin cycle and cell proliferation in human fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acid sphingomyelinase is not essential for the IL-1 and tumor necrosis factor receptor signaling pathway leading to NFkB activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor alpha activates NF-kappaB in acid sphingomyelinase-deficient mouse embryonic fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acid sphingomyelinase-derived ceramide is not required for inflammatory cytokine signalling in murine macrophages
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD28 signals through acidic sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acidic sphingomyelinase mediates entry of N. gonorrhoeae into nonphagocytic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acidic sphingomyelinase (ASM) is necessary for fas-induced GD3 ganglioside accumulation and efficient apoptosis of lymphoid cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD95 (Fas/APO-1) induces ceramide formation and apoptosis in the absence of a functional acid sphingomyelinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acid sphingomyelinase deficient mice: a model of types A and B Niemann-Pick disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparative study of the metabolic pools of sphingomyelin and phosphatidylcholine sensitive to tumor necrosis factor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Neurotrophins induce sphingomyelin hydrolysis. Modulation by co-expression of p75NTR with Trk receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Expression of neutral sphingomyelinase identifies a distinct pool of sphingomyelin involved in apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of acid sphingomyelinase by interleukin-1 (IL-1) requires the IL-1 receptor accessory protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The tumour necrosis factor-sensitive pool of sphingomyelin is resynthesized in a distinct compartment of the plasma membrane
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Association of p75(NTR) with caveolin and localization of neurotrophin-induced sphingomyelin hydrolysis to caveolae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide formation leads to caspase-3 activation during hypoxic PC12 cell death. Inhibitory effects of Bcl-2 on ceramide formation and caspase-3 activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tumor necrosis factor induces rapid production of 1'2'diacylglycerol by a phosphatidylcholine-specific phospholipase C.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Programmed cell death induced by ceramide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of neutral sphingomyelinase in human neutrophils by polyunsaturated fatty acids
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Redox-sensitive events in Fas-induced apoptosis in human NK cells include ceramide generation and protein tyrosine dephosphorylation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human caspases by peptide-based and macromolecular inhibitors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Proteolytic activities that mediate apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspases: enemies within
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CD95/Fas-induced ceramide formation proceeds with slow kinetics and is not blocked by caspase-3/CPP32 inhibition
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caspase-dependent ceramide production in Fas- and HLA class I-mediated peripheral T cell apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Evidence against an early signalling role for ceramide in Fas-mediated apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptosis and activation of the sphingomyelin-ceramide pathway induced by oxidized low density lipoproteins are not causally related in ECV-304 endothelial cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement of an ICE-like protease for induction of apoptosis and ceramide generation by REAPER.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide generation by the Reaper protein is not blocked by the caspase inhibitor, p35.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Double identity for proteins of the Bcl-2 family
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Influence of Bcl-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 interrupts the ceramide-mediated pathway of cell death.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distinct sites of action of Bcl-2 and Bcl-xL in the ceramide pathway of apoptosis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Implication of mitochondrial hydrogen peroxide generation in ceramide-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct Effect of Ceramide on the Mitochondrial Electron Transport Chain Leads to Generation of Reactive Oxygen Species
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
p53-dependent ceramide response to genotoxic stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FADD/MORT1 is a common mediator of CD95 (Fas/APO-1) and tumor necrosis factor receptor-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel cytoplasmic domain of the p55 tumor necrosis factor receptor initiates the neutral sphingomyelinase pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
FAN, a novel WD-repeat protein, couples the p55 TNF-receptor to neutral sphingomyelinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A ceramide-activated protein phosphatase mediates ceramide-induced G1 arrest of Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingolipids are potential heat stress signals in Saccharomyces
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Involvement of yeast sphingolipids in the heat stress response of Saccharomyces cerevisiae
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide triggers meiotic cell cycle progression in Xenopus oocytes. A potential mediator of progesterone-induced maturation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingoid base 1-phosphate phosphatase: a key regulator of sphingolipid metabolism and stress response.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Caenorhabditis elegans contains two distinct acid sphingomyelinases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sphingosylphosphorylcholine is a remarkably potent mitogen for a variety of cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phosphatidylcholine breakdown and signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The growing phospholipase A2 superfamily of signal transduction enzymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of phosphoinositide-specific phospholipase C isozymes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bimodal regulation of ceramidase by interleukin-1beta. Implications for the regulation of cytochrome p450 2C11.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Apoptotic signaling through CD95 (Fas/Apo-1) activates an acidic sphingomyelinase.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of caspase activity prevents anti-IgM induced apoptosis but not ceramide generation in WEHI 231 B cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The CD40-ligand stimulates T-lymphocytes via the neutral sphingomyelinase: a novel function of the CD40-ligand as signalling molecule
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
L-selectin stimulates the neutral sphingomyelinase and induces release of ceramide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential regulation of sphingomyelinase and ceramidase activities by growth factors and cytokines. Implications for cellular proliferation and differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mediator role of ceramide in the regulation of neuroblastoma Neuro2a cell differentiation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Role for ceramide in cell cycle arrest.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ceramide-independent CD28 and TCR signaling but reduced IL-2 secretion in T cells of acid sphingomyelinase-deficient mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of the anti-apoptotic PI(3)K/Akt/Bad pathway by stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Direct evidence for an important role of sphingomyelinase in ultraviolet-induced activation of c-Jun N-terminal kinase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipopolysaccharide induces disseminated endothelial apoptosis requiring ceramide generation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
CPP32 inhibition prevents Fas-induced ceramide generation and apoptosis in human cells.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Fas/CD95/Apo-I activates the acidic sphingomyelinase via caspases.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS1388-1981%2899%2900038-4
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S1388-1981(99)00038-4
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
PubMed ID
10216276
1 reference
stated in
Europe PubMed Central
PubMed ID
10216276
retrieved
28 July 2017
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