(Q42555356)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8706124%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

title

Acid sphingomyelinase-deficient human lymphoblasts and mice are defective in radiation-induced apoptosis (English)

1 reference

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17 October 2019

1 reference

1

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17 October 2019

Seamus Martin

4

1 reference

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17 October 2019

8

E H Schuchman

1 reference

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17 October 2019

author name string

L A Peña

2

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17 October 2019

A Haimovitz-Friedman

3

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17 October 2019

D Green

5

1 reference

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17 October 2019

M McLoughlin

6

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17 October 2019

C Cordon-Cardo

7

1 reference

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17 October 2019

Z Fuks

9

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17 October 2019

R Kolesnick

10

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17 October 2019

language of work or name

English

0 references

publication date

1 July 1996

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17 October 2019

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17 October 2019

volume

86

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17 October 2019

issue

2

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17 October 2019

page(s)

189-199

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Radiation-induced apoptosis: its role in a MADCaT (mitosis-apoptosis-differentiation-calcium toxicity) scheme of cytotoxicity mechanisms

17 October 2019

cites work

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7 January 2021

Use of cyclosporin A in establishing Epstein-Barr virus-transformed human lymphoblastoid cell lines

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7 January 2021

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

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7 January 2021

CD28 signals through acidic sphingomyelinase

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7 January 2021

Sublethal damage, potentially lethal damage, and chromosomal aberrations in mammalian cells exposed to ionizing radiations

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7 January 2021

The metabolism of sphingomyelin. II. Evidence of an enzymatic deficiency in Niemann-Pick diseae

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7 January 2021

Multiple pathways originate at the Fas/APO-1 (CD95) receptor: sequential involvement of phosphatidylcholine-specific phospholipase C and acidic sphingomyelinase in the propagation of the apoptotic signal.

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7 January 2021

Beneficial liaisons: radiobiology meets cellular and molecular biology

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7 January 2021

Chromosomal aberrations and mortality of x-irradiated mammalian cells: emphasis on repair

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7 January 2021

Radiation-induced apoptosis: Relevance to radiotherapy

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7 January 2021

Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System

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7 January 2021

Activation of Ras in vitro and in intact fibroblasts by the Vav guanine nucleotide exchange protein

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7 January 2021

FAS-induced apoptosis is mediated via a ceramide-initiated RAS signaling pathway

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7 January 2021

Ionizing radiation acts on cellular membranes to generate ceramide and initiate apoptosis

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7 January 2021

Ceramide: an intracellular signal for apoptosis

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7 January 2021

The nature of ataxia-telangiectasia: problems and perspectives

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7 January 2021

Acid sphingomyelinase deficient mice: a model of types A and B Niemann–Pick disease

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7 January 2021

Time lapse cinemicrographic studies of x-irradiated HeLa S3 cells. I. Cell progression and cell disintegration

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7 January 2021

Induction of apoptotic DNA damage and cell death by activation of the sphingomyelin pathway

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7 January 2021

Reduction of p53 gene dosage does not increase initiation or promotion but enhances malignant progression of chemically induced skin tumors.

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7 January 2021

Sphingomyelin and derivatives as cellular signals

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7 January 2021

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

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7 January 2021

Niemann-Pick type B disease. Identification of a single codon deletion in the acid sphingomyelinase gene and genotype/phenotype correlations in type A and B patients

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7 January 2021

Niemann-Pick disease: a frequent missense mutation in the acid sphingomyelinase gene of Ashkenazi Jewish type A and B patients

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7 January 2021

Compartmentalized Production of Ceramide at the Cell Surface

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7 January 2021

Cancer therapy and p53.

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7 January 2021

p53-dependent apoptosis modulates the cytotoxicity of anticancer agents

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7 January 2021

Purification and characterization of neutral and acid sphingomyelinases from rat brain.

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7 January 2021

Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1 beta

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7 January 2021

Residual DNA damage: what is left over and how does this determine cell fate?

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7 January 2021

Quantitation of free sphingosine in liver by high-performance liquid chromatography

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7 January 2021

PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid

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7 January 2021

Programmed cell death induced by ceramide

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7 January 2021

Acid sphingomyelinase-deficient mice mimic the neurovisceral form of human lysosomal storage disease (Niemann-Pick disease)

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7 January 2021

Evidence for a general relationship between the induced level of DNA double-strand breakage and cell-killing after X-irradiation of mammalian cells

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7 January 2021

Structural organization and complete nucleotide sequence of the gene encoding human acid sphingomyelinase (SMPD1)

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7 January 2021

Ionizing radiation induces apoptotic cell death in human TcR-gamma/delta+ T and natural killer cells without detectable p53 protein

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7 January 2021

The radiobiology of human cells and tissues. In vitro radiosensitivity. The picture has changed in the 1980s

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7 January 2021

DNA damage can induce apoptosis in proliferating lymphoid cells via p53-independent mechanisms inhibitable by Bcl-2

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7 January 2021

Retroviral-mediated transfer of the human acid sphingomyelinase cDNA: correction of the metabolic defect in cultured Niemann-Pick disease cells

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7 January 2021

Role for ceramide as an endogenous mediator of Fas-induced cytotoxicity

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7 January 2021

Properties and applications of human DNA repair genes

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7 January 2021

Proliferation Kinetics of X-irradiated Mouse L Cells Studied with Time-lapse Photography. II

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7 January 2021

Enzymatic quantification of sphingosine in the picomole range in cultured cells.

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7 January 2021

Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis.

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7 January 2021

Mice lacking ADPRT and poly(ADP-ribosyl)ation develop normally but are susceptible to skin disease

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7 January 2021

The complexity of DNA damage: relevance to biological consequences

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7 January 2021

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

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7 January 2021

Phosphorylation of Raf by ceramide-activated protein kinase

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7 January 2021

Effect of Triton X-100 on the hydrolysis of sphingomyelin by sphingomyelinase of rat brain

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7 January 2021

Fluorescence-Based Selection of Retrovirally Transduced Cells in the Absence of a Marker Gene: Direct Selection of Transduced Type B Niemann-Pick Disease Cells and Evidence for Bystander Correction

1 reference

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7 January 2021

Signaling through the sphingomyelin pathway

1 reference

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7 January 2021

10.1016/S0092-8674(00)80091-4

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:8706124%20AND%20SRC:MED&resulttype=core&format=json

17 October 2019

1 reference