(Q33601521)

28 July 2017

title

Multiple loss-of-function mechanisms contribute to SCN5A-related familial sick sinus syndrome (English)

1 reference

28 July 2017

1 reference

Ming Lei

6

0 references

author name string

Junhong Gui

1

1 reference

28 July 2017

Tao Wang

2

1 reference

28 July 2017

Richard P O Jones

3

1 reference

28 July 2017

Dorothy Trump

4

1 reference

28 July 2017

Thomas Zimmer

5

1 reference

28 July 2017

language of work or name

English

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publication date

7 June 2010

1 reference

28 July 2017

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28 July 2017

volume

5

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28 July 2017

issue

6

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28 July 2017

page(s)

e10985

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

7 June 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Mutation-specific effects of polymorphism H558R in SCN5A-related sick sinus syndrome

1 reference

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21 June 2018

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Sodium channel mutations and arrhythmias

21 June 2018

1 reference

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SCN5A channelopathies--an update on mutations and mechanisms

21 June 2018

1 reference

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Genetic Na+ channelopathies and sinus node dysfunction

21 June 2018

1 reference

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Correlations between clinical and physiological consequences of the novel mutation R878C in a highly conserved pore residue in the cardiac Na+ channel

21 June 2018

1 reference

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Cardiac ion channel gene mutations in sudden infant death syndrome

21 June 2018

1 reference

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SCN5A and sinoatrial node pacemaker function.

21 June 2018

1 reference

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A common SCN5A polymorphism attenuates a severe cardiac phenotype caused by a nonsense SCN5A mutation in a Chinese family with an inherited cardiac conduction defect

21 June 2018

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Molecular pathology of X linked retinoschisis: mutations interfere with retinoschisin secretion and oligomerisation

21 June 2018

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Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a

21 June 2018

1 reference

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Sodium channel mutations and susceptibility to heart failure and atrial fibrillation

21 June 2018

1 reference

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Reduced voltage dependence of inactivation in the SCN5A sodium channel mutation delF1617.

21 June 2018

1 reference

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SCN5A mutation associated with dilated cardiomyopathy, conduction disorder, and arrhythmia

21 June 2018

1 reference

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Congenital sick sinus syndrome caused by recessive mutations in the cardiac sodium channel gene (SCN5A)

21 June 2018

1 reference

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Contribution of sodium channel mutations to bradycardia and sinus node dysfunction in LQT3 families

21 June 2018

1 reference

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A cardiac sodium channel mutation cosegregates with a rare connexin40 genotype in familial atrial standstill

21 June 2018

1 reference

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The human heart and rat brain IIA Na+ channels interact with different molecular regions of the beta1 subunit

21 June 2018

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Intracellular retention of mutant retinoschisin is the pathological mechanism underlying X-linked retinoschisis

21 June 2018

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Novel SCN5A mutation leading either to isolated cardiac conduction defect or Brugada syndrome in a large French family

21 June 2018

1 reference

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Spectrum of mutations in long-QT syndrome genes. KVLQT1, HERG, SCN5A, KCNE1, and KCNE2

21 June 2018

1 reference

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SCN5A mutation (T1620M) causing Brugada syndrome exhibits different phenotypes when expressed in Xenopus oocytes and mammalian cells

21 June 2018

1 reference

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Cardiac conduction defects associate with mutations in SCN5A

21 June 2018

1 reference

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Genetic basis and molecular mechanism for idiopathic ventricular fibrillation

21 June 2018

1 reference

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Right bundle-branch block and ST-segment elevation in leads V1 through V3: a marker for sudden death in patients without demonstrable structural heart disease

21 June 2018

1 reference

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Molecular genetics of long QT syndrome from genes to patients

21 June 2018

1 reference

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Further characterization of the syndrome of right bundle branch block, ST segment elevation, and sudden cardiac death

21 June 2018

1 reference

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SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

21 June 2018

1 reference

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Electrical reversion of cardiac arrhythmias

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881866

Primary structure and functional expression of the human cardiac tetrodotoxin-insensitive voltage-dependent sodium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2881866

Voltage-gated Na+ channel transcript patterns in the mammalian heart are species-dependent.

21 June 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

Sodium channel gene (SCN5A) mutations in 44 index patients with Brugada syndrome: different incidences in familial and sporadic disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

A mutation in the human cardiac sodium channel (E161K) contributes to sick sinus syndrome, conduction disease and Brugada syndrome in two families

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

Is sodium current present in human sinoatrial node cells?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

SCN5A mutation associated with cardiac conduction defect and atrial arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

High risk for bradyarrhythmic complications in patients with Brugada syndrome caused by SCN5A gene mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

Congenital atrial standstill associated with coinheritance of a novel SCN5A mutation and connexin 40 polymorphisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0010985

Update on sick sinus syndrome, a cardiac disorder of aging

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20539757

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The sinus node function: normal and pathological

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20539757

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0010985

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference