(Q33603925)

28 July 2017

KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps (English)

1 reference

28 July 2017

0 references

Sara I Liin

3

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Santiago Rebolledo

2

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author name string

Rene Barro-Soria

1

1 reference

28 July 2017

Marta E Perez

4

1 reference

28 July 2017

Kevin J Sampson

5

1 reference

28 July 2017

Robert S Kass

6

1 reference

28 July 2017

H Peter Larsson

7

1 reference

28 July 2017

language of work or name

English

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publication date

28 April 2014

1 reference

28 July 2017

Nature Communications

1 reference

28 July 2017

5

1 reference

28 July 2017

3750

1 reference

https://scigraph.springernature.com/pub.10.1038/ncomms4750

28 July 2017

0 references

cites work

Single-channel basis for the slow activation of the repolarizing cardiac potassium current, I(Ks)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

IKs channels open slowly because KCNE1 accessory subunits slow the movement of S4 voltage sensors in KCNQ1 pore-forming subunits

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

KCNE1 enhances phosphatidylinositol 4,5-bisphosphate (PIP2) sensitivity of IKs to modulate channel activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

The specific slow afterhyperpolarization inhibitor UCL2077 is a subtype-selective blocker of the epilepsy associated KCNQ channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Arrhythmia in heart and brain: KCNQ1 mutations link epilepsy and sudden unexplained death.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

A multiscale model linking ion-channel molecular dynamics and electrostatics to the cardiac action potential

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

KCNQ1 and KCNE1 in the IKs channel complex make state-dependent contacts in their extracellular domains

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

KCNE peptides differently affect voltage sensor equilibrium and equilibration rates in KCNQ1 K+ channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

KCNE1 and KCNE3 stabilize and/or slow voltage sensing S4 segment of KCNQ1 channel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Chromanol 293B binding in KCNQ1 (Kv7.1) channels involves electrostatic interactions with a potassium ion in the selectivity filter

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

The role of S4 charges in voltage-dependent and voltage-independent KCNQ1 potassium channel complexes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

The KCNQ1 potassium channel: from gene to physiological function

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Molecular physiology of cardiac repolarization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Subunit interaction determines IKs participation in cardiac repolarization and repolarization reserve

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Long QT syndrome: from channels to cardiac arrhythmias

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

The cooperative voltage sensor motion that gates a potassium channel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Single-channel characteristics of wild-type IKs channels and channels formed with two minK mutants that cause long QT syndrome

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Cut-open oocyte voltage-clamp technique

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Activation and inactivation of homomeric KvLQT1 potassium channels.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Coassembly of K(V)LQT1 and minK (IsK) proteins to form cardiac I(Ks) potassium channel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

K(V)LQT1 and lsK (minK) proteins associate to form the I(Ks) cardiac potassium current

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Transfer of twelve charges is needed to open skeletal muscle Na+ channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Contribution of the S4 segment to gating charge in the Shaker K+ channel.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Shaker potassium channel gating. III: Evaluation of kinetic models for activation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

The size of gating charge in wild-type and mutant Shaker potassium channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4019390

Voltage sensor of Kv1.2: structural basis of electromechanical coupling

14 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS4750

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS4750

Denaturing high-performance liquid chromatography screening of the long QT syndrome-related cardiac sodium and potassium channel genes and identification of novel mutations and single nucleotide polymorphisms

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24769622

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCOMMS4750

1 reference

Dimensions Publication ID

28 July 2017

0 references

0 references

1 reference

28 July 2017

1 reference