(Q33605183)

28 July 2017

title

Conformational preferences of substrates for human prolyl 4-hydroxylase (English)

1 reference

28 July 2017

Ronald T Raines

4

0 references

Grant R Krow

series ordinal

3

object named as

Grant R Krow

1 reference

28 July 2017

1

Kelly L Gorres

1 reference

28 July 2017

Ram Edupuganti

2

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28 July 2017

language of work or name

English

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publication date

15 August 2008

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28 July 2017

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28 July 2017

volume

47

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28 July 2017

issue

36

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28 July 2017

page(s)

9447-9455

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Synthetic Biology of Proteins: Tuning GFPs Folding and Stability with Fluoroproline

28 July 2017

cites work

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21 June 2018

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Loss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null mice

21 June 2018

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Direct spectroscopic detection of a C-H-cleaving high-spin Fe(IV) complex in a prolyl-4-hydroxylase

21 June 2018

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2005 Emil Thomas Kaiser Award

21 June 2018

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Structure and mechanism of mouse cysteine dioxygenase

21 June 2018

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A stereoelectronic effect on turn formation due to proline substitution in elastin-mimetic polypeptides

21 June 2018

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Proline hydroxylation and gene expression

21 June 2018

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21 June 2018

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Cotranslational incorporation of a structurally diverse series of proline analogues in an Escherichia coli expression system.

21 June 2018

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Dioxygen activation at mononuclear nonheme iron active sites: enzymes, models, and intermediates

21 June 2018

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THE PREVALENCE AND SIGNIFICANCE OF THE PRODUCT INHIBITION OF ENZYMES

21 June 2018

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The exoskeleton collagens in Caenorhabditis elegans are modified by prolyl 4-hydroxylases with unique combinations of subunits

21 June 2018

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Insights on the conformational stability of collagen

21 June 2018

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Prolyl 4-hydroxylase is an essential procollagen-modifying enzyme required for exoskeleton formation and the maintenance of body shape in the nematode Caenorhabditis elegans

21 June 2018

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Prolyl 4-hydroxylase is required for viability and morphogenesis in Caenorhabditis elegans

21 June 2018

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Collagen hydroxylases and the protein disulfide isomerase subunit of prolyl 4-hydroxylases

21 June 2018

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Type-III procollagen assembly in semi-intact cells: chain association, nucleation and triple-helix folding do not require formation of inter-chain disulphide bonds but triple-helix nucleation does require hydroxylation

21 June 2018

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Collagens: molecular biology, diseases, and potentials for therapy

21 June 2018

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Ascorbate is consumed stoichiometrically in the uncoupled reactions catalyzed by prolyl 4-hydroxylase and lysyl hydroxylase

21 June 2018

1 reference

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Conformational implications of enzymatic proline hydroxylation in collagen

21 June 2018

1 reference

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Prolyl 4-hydroxylase activity in relation to the oxidation state of enzyme-bound iron. The role of ascorbate in peptidyl proline hydroxylation

21 June 2018

1 reference

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Decarboxylation of alpha-ketoglutarate coupled to collagen proline hydroxylase

21 June 2018

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Hydroxylation of (X-Pro-Gly)n by protocollagen proline hydroxylase. Effect of chain length, helical conformation and amino acid sequence in the substrate.

21 June 2018

1 reference

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The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple-helix of collagen

21 June 2018

1 reference

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21 June 2018

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Alternate substrates and inhibitors of bacterial 4-hydroxyphenylpyruvate dioxygenase

21 June 2018

1 reference

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Oligopeptide biases in protein sequences and their use in predicting protein coding regions in nucleotide sequences

21 June 2018

1 reference

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A single polypeptide acts both as the beta subunit of prolyl 4-hydroxylase and as a protein disulfide-isomerase

21 June 2018

1 reference

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Calculation of protein extinction coefficients from amino acid sequence data

21 June 2018

1 reference

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Protein hydroxylation: prolyl 4-hydroxylase, an enzyme with four cosubstrates and a multifunctional subunit

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Interaction of prolyl 4-hydroxylase with synthetic peptide substrates. A conformational model for collagen proline hydroxylation

21 June 2018

1 reference

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Site-directed mutagenesis of human protein disulphide isomerase: effect on the assembly, activity and endoplasmic reticulum retention of human prolyl 4-hydroxylase in Spodoptera frugiperda insect cells

21 June 2018

1 reference

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Characterization of the human prolyl 4-hydroxylase tetramer and its multifunctional protein disulfide-isomerase subunit synthesized in a baculovirus expression system

21 June 2018

1 reference

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Beta-turns in nascent procollagen are sites of posttranslational enzymatic hydroxylation of proline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Studies on the mechanism of reduction of prolyl hydroxylase activity by d,l-3,4 dehydroproline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

The role of ascorbate in the prolyl hydroxylase reaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Hydroxylation of proline in polytripeptide models of collagen: stereochemistry of polytripeptide-prolyl hydroxylase interaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

The in vivo inhibition of collagen synthesis and the reduction of prolyl hydroxylase activity by 3,4-dehydroproline

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Effect of L-3,4-dehydroproline on collagen synthesis and prolyl hydroxylase activity in mammalian cell cultures

21 June 2018

1 reference

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5-Carboxy-2-azabicyclo[2.1.1]hexanes as precursors of 5-halo, amino, phenyl, and 2-methoxycarbonylethyl methanopyrrolidines

21 June 2018

1 reference

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Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

High-level production of human collagen prolyl 4-hydroxylase in Escherichia coli

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

The rearrangement route to 3-carboxy- and 3-hydroxymethyl-2-azabicyclo[2.1.1]hexanes: 3,5-methanoprolines

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Substituted 2-azabicyclo[2.1.1]hexanes as constrained proline analogues: implications for collagen stability

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Production of human prolyl 4-hydroxylase in Escherichia coli

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Neoglycopeptides as inhibitors of oligosaccharyl transferase: insight into negotiating product inhibition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Collagen stability: insights from NMR spectroscopic and hybrid density functional computational investigations of the effect of electronegative substituents on prolyl ring conformations

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Understanding the role of stereoelectronic effects in determining collagen stability. 1. A quantum mechanical study of proline, hydroxyproline, and fluoroproline dipeptide analogues in aqueous solution

30 October 2018

1 reference

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Conformational stability of collagen relies on a stereoelectronic effect.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2810141

Site-directed mutagenesis of the alpha subunit of human prolyl 4-hydroxylase. Identification of three histidine residues critical for catalytic activity

30 October 2018

1 reference

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Effect of Polymer Size on the Inhibition of Protocollagen Proline Hydroxylase by Polyproline II

30 October 2018

1 reference

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Inductive effects on the structure of proline residues

30 October 2018

1 reference

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Substrate specificity of human prolyl-4-hydroxylase

30 October 2018

1 reference

12 December 2020

Proline editing: a divergent strategy for the synthesis of conformationally diverse peptides

1 reference

12 December 2020

Gly-X-Y tripeptide frequencies in collagen: a context for host-guest triple-helical peptides

1 reference

12 December 2020

A non-heme iron protein with heme tendencies: an investigation of the substrate specificity of thymine hydroxylase

1 reference

12 December 2020

Complex-induced proximity effects. Temperature-dependent regiochemical diversity in lithiation-electrophilic substitution reactions of N-BOC-2-azabicyclo[2.1.1]hexane. 2,4- and 3,5-methanoprolines

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12 December 2020

Fluoroprolines as Tools for Protein Design and Engineering We thank Mrs. E. Weyher for skillful technical assistance in spectroscopic analyses and Mrs. W. Wenger for her excellent technical assistance in protein preparation. We are indebted to Dr. R

1 reference

12 December 2020

10 Posttranslational enzymes in the biosynthesis of collagen: Intracellular enzymes

1 reference

12 December 2020

Simultaneous incorporation of 18 O into succinate and hydroxyproline catalyzed by collagen proline hydroxylase

1 reference

12 December 2020

Syncatalytic inactivation of prolyl 4-hydroxylase by synthetic peptides containing the unphysiologic amino acid 5-oxaproline

1 reference

12 December 2020

Synthetic polypeptides as substrates and inhibitors of collagen proline hydroxylase

1 reference

12 December 2020

Identifiers

DOI

10.1021/BI8009373

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28 July 2017

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28 July 2017

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