(Q33609699)

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Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27055731%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Targeting tumour-associated macrophages with CCR2 inhibition in combination with FOLFIRINOX in patients with borderline resectable and locally advanced pancreatic cancer: a single-centre, open-label, dose-finding, non-randomised, phase 1b trial (English)

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31 March 2020

pancreatic cancer

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Kathryn J Fowler

11

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31 March 2020

15

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31 March 2020

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Timothy M Nywening

1

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31 March 2020

Andrea Wang-Gillam

2

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31 March 2020

Dominic E Sanford

3

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31 March 2020

Brian A Belt

4

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31 March 2020

Roheena Z Panni

5

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31 March 2020

Brian M Cusworth

6

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31 March 2020

Adetunji T Toriola

7

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31 March 2020

Rebecca K Nieman

8

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31 March 2020

Lori A Worley

9

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31 March 2020

Motoyo Yano

10

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31 March 2020

A Craig Lockhart

12

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31 March 2020

Rama Suresh

13

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31 March 2020

Benjamin R Tan

14

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31 March 2020

Ryan C Fields

16

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31 March 2020

Steven M Strasberg

17

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31 March 2020

William G Hawkins

18

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31 March 2020

David G DeNardo

19

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31 March 2020

S Peter Goedegebuure

20

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31 March 2020

David C Linehan

21

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31 March 2020

publication date

4 April 2016

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31 March 2020

Lancet Oncology Commission

1 reference

Europe PubMed Central

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31 March 2020

17

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Europe PubMed Central

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31 March 2020

5

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Europe PubMed Central

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31 March 2020

651-662

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27055731%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Cancer statistics, 2014

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Increased survival in pancreatic cancer with nab-paclitaxel plus gemcitabine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Outcomes with FOLFIRINOX for borderline resectable and locally unresectable pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Utilizing pharmacokinetics/pharmacodynamics modeling to simultaneously examine free CCL2, total CCL2 and carlumab (CNTO 888) concentration time data.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

FOLFIRINOX in locally advanced pancreatic cancer: the Massachusetts General Hospital Cancer Center experience

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Multi-institutional experience with FOLFIRINOX in pancreatic adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Phase 2 study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 (CCL2), in metastatic castration-resistant prostate cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

A retrospective study of neoadjuvant FOLFIRINOX in unresectable or borderline-resectable locally advanced pancreatic adenocarcinoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Coordinated regulation of myeloid cells by tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Monocyte recruitment during infection and inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

FOLFIRINOX versus gemcitabine for metastatic pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Macrophage diversity enhances tumor progression and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Mechanism of T cell tolerance induced by myeloid-derived suppressor cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Immunological aspects of cancer chemotherapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Regulation of immune responses by L-arginine metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

21 June 2018

CSF1R inhibition with emactuzumab in locally advanced diffuse-type tenosynovial giant cell tumours of the soft tissue: a dose-escalation and dose-expansion phase 1 study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

30 October 2018

FOLFIRINOX for locally advanced pancreatic adenocarcinoma: results of an AGEO multicenter prospective observational cohort.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

30 October 2018

Pancreatic Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5407285

30 October 2018

Dynamics of the immune reaction to pancreatic cancer from inception to invasion

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2816%2900078-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Recruitment of a myeloid cell subset (CD11b/Gr1mid) via CCL2/CCR2 promotes the development of colorectal cancer liver metastasis*

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2816%2900078-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1470-2045%2816%2900078-4

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1016/S1470-2045(16)00078-4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27055731%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

PMC publication ID

1 reference

Europe PubMed Central

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31 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27055731%20AND%20SRC:MED&resulttype=core&format=json

31 March 2020

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