(Q36586333)

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Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses

scientific article published on 5 December 2012

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scholarly article

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23221383%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses (English)

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19 February 2020

immunosuppression

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Stephen M. Hewitt

11

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19 February 2020

Jonathan B. Mitchem

1

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19 February 2020

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19 February 2020

William M Gallagher

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19 February 2020

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19 February 2020

David Piwnica-Worms

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David Piwnica-Worms

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19 February 2020

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Donal J Brennan

2

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19 February 2020

Brett L Knolhoff

3

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19 February 2020

Brian A Belt

4

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19 February 2020

Dominic E Sanford

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19 February 2020

Larisa Belaygorod

7

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19 February 2020

Danielle Carpenter

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19 February 2020

Lynne Collins

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19 February 2020

Girish Mallya Udupi

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19 February 2020

Craig Wegner

14

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19 February 2020

Andrea Wang-Gillam

16

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19 February 2020

Peter Goedegebuure

17

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19 February 2020

David C Linehan

18

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19 February 2020

David G DeNardo

19

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19 February 2020

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5 December 2012

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19 February 2020

Cancer Research

1 reference

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19 February 2020

73

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19 February 2020

3

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19 February 2020

1128-1141

1 reference

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19 February 2020

Oncogenic Kras-induced GM-CSF production promotes the development of pancreatic neoplasia

1 reference

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9 September 2017

Tumor-derived granulocyte-macrophage colony-stimulating factor regulates myeloid inflammation and T cell immunity in pancreatic cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance

1 reference

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9 September 2017

Marginating dendritic cells of the tumor microenvironment cross-present tumor antigens and stably engage tumor-specific T cells

1 reference

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9 September 2017

Coordinated regulation of myeloid cells by tumours

1 reference

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9 September 2017

Interactions between cancer stem cells and their niche govern metastatic colonization

1 reference

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9 September 2017

Macrophages and cathepsin proteases blunt chemotherapeutic response in breast cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

1 reference

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9 September 2017

Therapeutic siRNA silencing in inflammatory monocytes in mice

1 reference

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9 September 2017

Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Hallmarks of Cancer: The Next Generation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Macrophage diversity enhances tumor progression and metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Immunity, Inflammation, and Cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

IL-4 induces cathepsin protease activity in tumor-associated macrophages to promote cancer growth and invasion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Glioma-associated cancer-initiating cells induce immunosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer

1 reference

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9 September 2017

Generation of orthotopic and heterotopic human pancreatic cancer xenografts in immunodeficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

STAT3 is required for proliferation and maintenance of multipotency in glioblastoma stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Deletion of vascular endothelial growth factor in myeloid cells accelerates tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3563931

9 September 2017

Novel image analysis approach for quantifying expression of nuclear proteins assessed by immunohistochemistry: application to measurement of oestrogen and progesterone receptor levels in breast cancer

1 reference

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9 September 2017

Exploring the role of cancer stem cells in radioresistance

1 reference

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9 September 2017

Discovery of a selective inhibitor of oncogenic B-Raf kinase with potent antimelanoma activity

1 reference

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9 September 2017

Activation of the PTEN/mTOR/STAT3 pathway in breast cancer stem-like cells is required for viability and maintenance

1 reference

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9 September 2017

Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

1 reference

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9 September 2017

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1 reference

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9 September 2017

Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma

1 reference

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9 September 2017

The macrophage growth factor CSF-1 in mammary gland development and tumor progression

1 reference

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30 September 2017

STAT3 plays a critical role in KRAS-induced pancreatic tumorigenesis.

1 reference

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Endothelial cell-initiated signaling promotes the survival and self-renewal of cancer stem cells

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30 September 2017

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12 December 2020

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23221383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

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1 reference

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12 December 2020

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1 reference

https://pubmed.ncbi.nlm.nih.gov/23221383

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1158/0008-5472.CAN-12-2731

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23221383%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23221383%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23221383%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

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