(Q24652600)

28

0 references

Nikolas K. Haass

Nikolas K Haass

10

0 references

Sung-Hou Kim

27

Sung-Hou Kim

0 references

Rafe Shellooe

25

Rafe Shellooe

0 references

Gideon Bollag

38

Gideon Bollag

0 references

Gaston Habets

32

Gaston Habets

0 references

Meenhard Herlyn

37

Meenhard Herlyn

0 references

Keiran S M Smalley

13

Keiran S M Smalley

0 references

Chao Zhang

33

Chao Zhang

0 references

Sam Gillette

8

Sam Gillette

0 references

Kam Y J Zhang

29

Kam Y J Zhang

0 references

Prabha N Ibrahim

34

Prabha N Ibrahim

0 references

Dean R Artis

36

Dean R Artis

0 references

Katrin Sproesser

11

Katrin Sproesser

0 references

author name string

James Tsai

1

0 references

John T Lee

2

0 references

Weiru Wang

3

0 references

Jiazhong Zhang

4

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Hanna Cho

5

0 references

Shumeye Mamo

6

0 references

Ryan Bremer

7

0 references

Jun Kong

9

0 references

Ling Li

12

0 references

Daniel Fong

14

0 references

Yong-Liang Zhu

15

0 references

Adhirai Marimuthu

16

0 references

Hoa Nguyen

17

0 references

Billy Lam

18

0 references

Jennifer Liu

19

0 references

Ivana Cheung

20

0 references

Julie Rice

21

0 references

Yoshihisa Suzuki

22

0 references

Catherine Luu

23

0 references

Calvin Settachatgul

24

0 references

John Cantwell

26

0 references

Brian L West

30

0 references

Ben Powell

31

0 references

Peter Hirth

Proceedings of the National Academy of Sciences of the United States of America

35

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language of work or name

English

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publication date

26 February 2008

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published in

0 references

volume

105

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page(s)

3041-6

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issue

8

0 references

cites work

Constitutive activation of the Ras-Raf signaling pathway in metastatic melanoma is associated with poor prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Demonstration of a genetic therapeutic index for tumors expressing oncogenic BRAF by the kinase inhibitor SB-590885

7 April 2017

1 reference

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Mutations of the BRAF gene in human cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Mechanism of activation of the RAF-ERK signaling pathway by oncogenic mutations of B-RAF

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

The discovery of potent cRaf1 kinase inhibitors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

BRAF mutation predicts sensitivity to MEK inhibition

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

BRAFE600-associated senescence-like cell cycle arrest of human naevi

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

7 April 2017

1 reference

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B-Raf kinase inhibitors for cancer treatment

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Recent advances in the research and development of RAF kinase inhibitors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Multiple signaling pathways must be targeted to overcome drug resistance in cell lines derived from melanoma metastases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Novel inhibitors of B-RAF based on a disubstituted pyrazine scaffold. Generation of a nanomolar lead

28 September 2017

1 reference

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A family of phosphodiesterase inhibitors discovered by cocrystallography and scaffold-based drug design

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Regulation of Raf-1 by direct feedback phosphorylation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

28 September 2017

Targeted cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

High frequency of BRAF mutations in nevi

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Discovery of a novel Raf kinase inhibitor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Human melanoma progression in skin reconstructs : biological significance of bFGF.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Paradoxical activation of Raf by a novel Raf inhibitor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2268581

Crystal structures of proto-oncogene kinase Pim1: a target of aberrant somatic hypermutations in diffuse large cell lymphoma

28 September 2017

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711741105

A negative feedback signaling network underlies oncogene-induced senescence

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0711741105

Targeting tyrosine kinases in cancer: the second wave

21 January 2018

1 reference

12 December 2020

The oncogene BRAFV600E is associated with a high risk of recurrence and less differentiated papillary thyroid carcinoma due to the impairment of Na+/I− targeting to the membrane

1 reference

12 December 2020

Poor Survival Associated with theBRAFV600E Mutation in Microsatellite-Stable Colon Cancers

1 reference

12 December 2020

Distribution and activity of antineoplastic drugs in a tumor model

1 reference

12 December 2020

Cell culture as spheroids: an approach to multicellular resistance

1 reference

12 December 2020

Oncogenic BRAF is required for tumor growth and maintenance in melanoma models

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0711741105

1 reference

2469377

ADS bibcode

2008PNAS..105.3041T

0 references

2469377

1 reference

1 reference

1 reference