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Isoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin.
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Europe PubMed Central
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4021470
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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610942%20AND%20SRC:MED&resulttype=core&format=json
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10 March 2020
title
Isoform 5 of PIPKIγ regulates the endosomal trafficking and degradation of E-cadherin
(English)
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4021470
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10 March 2020
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Nicholas J Schill
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1
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Europe PubMed Central
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4021470
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10 March 2020
Richard A. Anderson
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4
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4021470
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10 March 2020
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Andrew C Hedman
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2
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10 March 2020
Suyong Choi
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3
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10 March 2020
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7 March 2014
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10 March 2020
published in
Journal of Cell Science
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PMC publication ID
4021470
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10 March 2020
volume
127
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Europe PubMed Central
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4021470
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10 March 2020
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Pt 10
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10 March 2020
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2189-2203
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Europe PubMed Central
PMC publication ID
4021470
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10 March 2020
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Type I gamma phosphatidylinositol phosphate kinase modulates adherens junction and E-cadherin trafficking via a direct interaction with mu 1B adaptin
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A loss-of-function screen reveals SNX5 and SNX6 as potential components of the mammalian retromer
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Raf plus TGFbeta-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin
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Type Igamma661 phosphatidylinositol phosphate kinase directly interacts with AP2 and regulates endocytosis
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Sorting nexins
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14 July 2018
Phosphatidylinositol-4-phosphate 5-kinase gamma is associated with cell-cell junction in A431 epithelial cells
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14 July 2018
Phosphatidylinositol phosphate kinase type Igamma directly associates with and regulates Shp-1 tyrosine phosphatase.
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14 July 2018
Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases
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Rab11 in recycling endosomes regulates the sorting and basolateral transport of E-cadherin
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14 July 2018
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14 July 2018
Sorting nexins--unifying trends and new perspectives
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14 July 2018
Lysosomal targeting of E-cadherin: a unique mechanism for the down-regulation of cell-cell adhesion during epithelial to mesenchymal transitions
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14 July 2018
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14 July 2018
Clathrin isoform CHC22, a component of neuromuscular and myotendinous junctions, binds sorting nexin 5 and has increased expression during myogenesis and muscle regeneration
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14 July 2018
A novel neuronal-specific splice variant of Type I phosphatidylinositol 4-phosphate 5-kinase isoform gamma
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14 July 2018
Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch
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14 July 2018
Endocytosis of Epithelial Apical Junctional Proteins by a Clathrin-mediated Pathway into a Unique Storage Compartment
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14 July 2018
Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its Place
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14 July 2018
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14 July 2018
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14 July 2018
Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions
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14 July 2018
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin
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14 July 2018
Phosphoinositides and signal transduction
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14 July 2018
Subcellular localization of phosphatidylinositol 4,5-bisphosphate using the pleckstrin homology domain of phospholipase C delta1.
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14 July 2018
Pleckstrin homology domains and the cytoskeleton
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14 July 2018
Hakai, a c-Cbl-like protein, ubiquitinates and induces endocytosis of the E-cadherin complex
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14 July 2018
FYVE and coiled-coil domains determine the specific localisation of Hrs to early endosomes
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14 July 2018
PI(4,5)P(2) regulation of surface membrane traffic
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Hrs interacts with sorting nexin 1 and regulates degradation of epidermal growth factor receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Phosphatidylinositol 4-phosphate 5-kinase type I is regulated through phosphorylation response by extracellular stimuli
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Src-mediated activation of alpha-diacylglycerol kinase is required for hepatocyte growth factor-induced cell motility.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Signaling from E-cadherins to the MAPK pathway by the recruitment and activation of epidermal growth factor receptors upon cell-cell contact formation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
E-cadherin-catenin cell-cell adhesion complex and human cancer
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Coupled inositide phosphorylation and phospholipase D activation initiates clathrin-coat assembly on lysosomes.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Beta-catenin mediates the interaction of the cadherin-catenin complex with epidermal growth factor receptor
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
14 July 2018
Clathrin and phosphatidylinositol-4,5-bisphosphate regulate autophagic lysosome reformation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
Arl5b is a Golgi-localised small G protein involved in the regulation of retrograde transport.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
Inhibition of tumor growth and metastasis by depletion of vesicular sorting protein Hrs: its regulatory role on E-cadherin and beta-catenin.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
EGFR regulates RhoA-GTP dependent cell motility in E-cadherin mutant cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
The prognostic role of a gene signature from tumorigenic breast-cancer cells.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
Structural basis for phosphatidylinositol phosphate kinase type Igamma binding to talin at focal adhesions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
Activation of SGK1 by HGF, Rac1 and integrin-mediated cell adhesion in MDCK cells: PI-3K-dependent and -independent pathways.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
E-cadherin and Hakai: signalling, remodeling or destruction?
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
Hrs regulates endosome membrane invagination and tyrosine kinase receptor signaling in Drosophila
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4021470
retrieved
30 October 2018
Rac Activation upon Cell-Cell Contact Formation Is Dependent on Signaling from the Epidermal Growth Factor Receptor
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24610942
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Continual expression of Rab5(Q79L) causes a ligand-independent EGFR internalization and diminishes EGFR activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24610942
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Density-dependent inhibition of growth involves prevention of EGF receptor activation by E-cadherin-mediated cell-cell adhesion
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24610942
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Autophosphorylation of type I phosphatidylinositol phosphate kinase regulates its lipid kinase activity
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24610942
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1242/JCS.132423
1 reference
stated in
Europe PubMed Central
PMC publication ID
4021470
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610942%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
PMC publication ID
4021470
1 reference
stated in
Europe PubMed Central
PMC publication ID
4021470
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610942%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
PubMed publication ID
24610942
1 reference
stated in
Europe PubMed Central
PMC publication ID
4021470
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24610942%20AND%20SRC:MED&resulttype=core&format=json
retrieved
10 March 2020
ResearchGate publication ID
260647355
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