(Q33616477)

28 July 2017

Recreation of the terminal events in physiological integrin activation (English)

1 reference

28 July 2017

Feng Ye

1

1 reference

28 July 2017

Guiqing Hu

2

1 reference

28 July 2017

Dianne Taylor

3

1 reference

28 July 2017

Boris Ratnikov

4

1 reference

28 July 2017

Andrey A Bobkov

5

1 reference

28 July 2017

Mark A McLean

6

1 reference

28 July 2017

Stephen G Sligar

7

1 reference

28 July 2017

Kenneth A Taylor

8

1 reference

28 July 2017

Mark H Ginsberg

9

1 reference

28 July 2017

language of work or name

English

0 references

publication date

4 January 2010

1 reference

28 July 2017

17

1 reference

inferred from page(s)

published in

Journal of Cell Biology

1 reference

28 July 2017

188

1 reference

28 July 2017

157-173

1 reference

28 July 2017

1

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2812850/fullTextXML

inferred from PubMed Central ID database lookup

cites work

The Kindlin protein family: new members to the club of focal adhesion proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

The tail of integrins, talin, and kindlins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

The structure of the integrin alphaIIbbeta3 transmembrane complex explains integrin transmembrane signalling

21 June 2018

1 reference

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Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells

21 June 2018

1 reference

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Mechanically activated integrin switch controls alpha5beta1 function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Structure of a Complete Integrin Ectodomain in a Physiologic Resting State and Activation and Deactivation by Applied Forces

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

21 June 2018

1 reference

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Migfilin, a molecular switch in regulation of integrin activation

21 June 2018

1 reference

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Structural basis of the migfilin-filamin interaction and competition with integrin beta tails

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Particle-verification for single-particle, reference-based reconstruction using multivariate data analysis and classification

21 June 2018

1 reference

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Kindlin-2 controls bidirectional signaling of integrins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Kindlin-2 (Mig-2): a co-activator of beta3 integrins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Integrin alpha IIb beta 3 in a membrane environment remains the same height after Mn2+ activation when observed by cryoelectron tomography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Kindlin-3 is essential for integrin activation and platelet aggregation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Loss of talin1 in platelets abrogates integrin activation, platelet aggregation, and thrombus formation in vitro and in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Talin is required for integrin-mediated platelet function in hemostasis and thrombosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

The antithrombotic potential of selective blockade of talin-dependent integrin alpha IIb beta 3 (platelet GPIIb-IIIa) activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

On the freezing and identification of lipid monolayer 2-D arrays for cryoelectron microscopy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Tests of the extension and deadbolt models of integrin activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Structural basis of integrin activation by talin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

How the headpiece hinge angle is opened: New insights into the dynamics of integrin activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

A method of focused classification, based on the bootstrap 3D variance analysis, and its application to EF-G-dependent translocation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

The molecular basis of filamin binding to integrins and competition with talin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Electron tomography reveals diverse conformations of integrin alphaIIbbeta3 in the active state

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

A specific interface between integrin transmembrane helices and affinity for ligand

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Integrins: dynamic scaffolds for adhesion and signaling in platelets

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

The Kindler syndrome protein is regulated by transforming growth factor-beta and involved in integrin-mediated adhesion.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Integrin avidity regulation: are changes in affinity and conformation underemphasized?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Structure of integrin alpha5beta1 in complex with fibronectin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Conditional suppression of cellular genes: lentivirus vector-mediated drug-inducible RNA interference

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Migfilin and Mig-2 link focal adhesions to filamin and the actin cytoskeleton and function in cell shape modulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Structural determinants of integrin recognition by talin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Three-dimensional model of the human platelet integrin alpha IIbbeta 3 based on electron cryomicroscopy and x-ray crystallography

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Integrins: bidirectional, allosteric signaling machines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Modern analytical ultracentrifugation in protein science: a tutorial review

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Conformational regulation of integrin structure and function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Crystal structure of the extracellular segment of integrin alpha Vbeta3 in complex with an Arg-Gly-Asp ligand

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Crystal structure of the extracellular segment of integrin alpha Vbeta3

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Binding of a fibrinogen mimetic stabilizes integrin alphaIIbbeta3's open conformation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Calpain cleavage promotes talin binding to the beta 3 integrin cytoplasmic domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Class- and splice variant-specific association of CD98 with integrin beta cytoplasmic domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

EMAN: semiautomated software for high-resolution single-particle reconstructions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Are changes in integrin affinity and conformation overemphasized?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Design of potent and specific integrin antagonists. Peptide antagonists with high specificity for glycoprotein IIb-IIIa

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Long range propagation of conformational changes in integrin alpha IIb beta 3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Calpain cleavage of the cytoplasmic domain of the integrin beta 3 subunit

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Integrin cytoplasmic domains mediate inside-out signal transduction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Purification and properties of human platelet P235. A high molecular weight protein substrate of endogenous calcium-activated protease(s)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Hetrogeneity of human platelets. 3. Glycogen metabolism in platelets of different sizes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Quantitation of membrane glycoprotein IIIa on intact human platelets using the monoclonal antibody, AP-3.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Ligands "activate" integrin alpha IIb beta 3 (platelet GPIIb-IIIa).

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Monoclonal antibodies to ligand-occupied conformers of integrin alpha IIb beta 3 (glycoprotein IIb-IIIa) alter receptor affinity, specificity, and function.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Reversible conformational changes induced in glycoprotein IIb-IIIa by a potent and selective peptidomimetic inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Competition for talin results in trans-dominant inhibition of integrin activation

21 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Directed self-assembly of monodisperse phospholipid bilayer Nanodiscs with controlled size

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Reconstructing and deconstructing agonist-induced activation of integrin alphaIIbbeta3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Classification of heterogeneous electron microscopic projections into homogeneous subsets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

SILAC mouse for quantitative proteomics uncovers kindlin-3 as an essential factor for red blood cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Activation of integrin alphaIIbbeta3 by modulation of transmembrane helix associations

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Identification of a Talin-binding Site in the Integrin β3Subunit Distinct from the NPLY Regulatory Motif of Post-ligand Binding Functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

The MIG-2/integrin interaction strengthens cell-matrix adhesion and modulates cell motility.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Global conformational rearrangements in integrin extracellular domains in outside-in and inside-out signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Structural Studies of Cytoskeletal Protein Arrays Formed on Lipid Monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Energy-filtered electron microscopy reveals that talin is a highly flexible protein composed of a series of globular domains.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200908045

Analysis of GPIIb/IIIa receptor number by quantification of 7E3 binding to human platelets.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2812850

Accurate marker-free alignment with simultaneous geometry determination and reconstruction of tilt series in electron tomography

30 October 2018

1 reference

12 December 2020

Activation of leukocyte beta2 integrins by conversion from bent to extended conformations

1 reference

12 December 2020

Purification of glycoproteins IIb and III from human platelet plasma membranes and characterization of a calcium-dependent glycoprotein IIb-III complex

1 reference

12 December 2020

Three-dimensional reconstruction of imperfect two-dimensional crystals

1 reference

12 December 2020

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation

1 reference

12 December 2020

Modulation of the affinity of integrin alpha IIb beta 3 (GPIIb-IIIa) by the cytoplasmic domain of alpha IIb

1 reference

12 December 2020

A detailed molecular belt model for apolipoprotein A-I in discoidal high density lipoprotein

1 reference

12 December 2020

Kinetic determination of focal adhesion protein formation

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200908045

1 reference

28 July 2017

1 reference

28 July 2017

1 reference