(Q33617148)

28 July 2017

title

The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies (English)

1 reference

28 July 2017

1 reference

4

Tim P Morris

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28 July 2017

3

Caroline J Doré

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28 July 2017

Brennan C Kahan

1

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28 July 2017

Vipul Jairath

series ordinal

2

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28 July 2017

publication date

23 April 2014

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28 July 2017

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28 July 2017

volume

15

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28 July 2017

page(s)

139

1 reference

Bias, precision and statistical power of analysis of covariance in the analysis of randomized trials with baseline imbalance: a simulation study

28 July 2017

cites work

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21 June 2018

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21 June 2018

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Covariate adjustment increased power in randomized controlled trials: an example in traumatic brain injury

21 June 2018

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Improper analysis of trials randomised using stratified blocks or minimisation

21 June 2018

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Mortality from acute upper gastrointestinal bleeding in the United kingdom: does it display a "weekend effect"?

21 June 2018

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Comparing methods to estimate treatment effects on a continuous outcome in multicentre randomized controlled trials: a simulation study

21 June 2018

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Reduced sample sizes for atrophy outcomes in Alzheimer's disease trials: baseline adjustment

21 June 2018

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Reporting on covariate adjustment in randomised controlled trials before and after revision of the 2001 CONSORT statement: a literature review

21 June 2018

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A simulation study evaluating approaches to the analysis of ordinal outcome data in randomized controlled trials in traumatic brain injury: results from the IMPACT Project

21 June 2018

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A substantial and confusing variation exists in handling of baseline covariates in randomized controlled trials: a review of trials published in leading medical journals

21 June 2018

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Granulocyte-macrophage colony stimulating factor administered as prophylaxis for reduction of sepsis in extremely preterm, small for gestational age neonates (the PROGRAMS trial): a single-blind, multicentre, randomised controlled trial

21 June 2018

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Adjustment for strong predictors of outcome in traumatic brain injury trials: 25% reduction in sample size requirements in the IMPACT study.

21 June 2018

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Subgroup analysis and covariate adjustment in randomized clinical trials of traumatic brain injury: a systematic review.

21 June 2018

1 reference

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The method of minimization for allocation to clinical trials. a review

21 June 2018

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Subgroup analysis, covariate adjustment and baseline comparisons in clinical trial reporting: current practice and problems

21 June 2018

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How to select covariates to include in the analysis of a clinical trial

21 June 2018

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21 June 2018

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Subgroup analysis and other (mis)uses of baseline data in clinical trials

21 June 2018

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Should we adjust for covariates in nonlinear regression analyses of randomized trials?

21 June 2018

1 reference

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21 June 2018

1 reference

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Beneficial effect of azathioprine and prediction of prognosis in primary biliary cirrhosis. Final results of an international trial

21 June 2018

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Sequential Treatment Assignment with Balancing for Prognostic Factors in the Controlled Clinical Trial

21 June 2018

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Randomized Controlled Trials With Time-to-Event Outcomes: How Much Does Prespecified Covariate Adjustment Increase Power?

21 June 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

Covariate adjustment in randomized controlled trials with dichotomous outcomes increases statistical power and reduces sample size requirements

21 January 2018

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https://api.crossref.org/works/10.1186%2F1745-6215-15-139

The effect of omitted covariates on confidence interval and study power in binary outcome analysis: a simulation study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

Intrapleural use of tissue plasminogen activator and DNase in pleural infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

ANCOVA versus change from baseline had more power in randomized studies and more bias in nonrandomized studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

National audit of the use of surgery and radiological embolization after failed endoscopic haemostasis for non-variceal upper gastrointestinal bleeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

Prevalence, management, and outcomes of patients with coagulopathy after acute nonvariceal upper gastrointestinal bleeding in the United Kingdom

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

ISSLS prize winner: Function After Spinal Treatment, Exercise, and Rehabilitation (FASTER): a factorial randomized trial to determine whether the functional outcome of spinal surgery can be improved

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1745-6215-15-139

Interferon-alpha and survival in metastatic renal carcinoma: early results of a randomised controlled trial. Medical Research Council Renal Cancer Collaborators

21 January 2018

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12 December 2020

ICH Harmonised Tripartite Guideline. Statistical principles for clinical trials. International Conference on Harmonisation E9 Expert Working Group

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12 December 2020

Outcomes following acute nonvariceal upper gastrointestinal bleeding in relation to time to endoscopy: results from a nationwide study

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12 December 2020

Adjusting for partially missing baseline measurements in randomized trials

1 reference

12 December 2020

Identifiers

DOI

10.1186/1745-6215-15-139

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference