(Q33617754)

28 July 2017

title

G×G×E for lifespan in Drosophila: mitochondrial, nuclear, and dietary interactions that modify longevity (English)

1 reference

28 July 2017

0 references

1 reference

Chen-Tseh Zhu

1

1 reference

28 July 2017

Paul Ingelmo

series ordinal

2

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28 July 2017

David M Rand

series ordinal

3

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28 July 2017

publication date

15 May 2014

1 reference

28 July 2017

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28 July 2017

volume

10

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28 July 2017

issue

5

1 reference

28 July 2017

page(s)

e1004354

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Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

15 May 2014

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Mitonuclear protein imbalance as a conserved longevity mechanism

14 July 2018

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An Incompatibility between a mitochondrial tRNA and its nuclear-encoded tRNA synthetase compromises development and fitness in Drosophila

14 July 2018

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Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome

14 July 2018

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Epistasis dominates the genetic architecture of Drosophila quantitative traits

14 July 2018

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Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction

14 July 2018

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14 July 2018

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Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

14 July 2018

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Identification of functional elements and regulatory circuits by Drosophila modENCODE

14 July 2018

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Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation

14 July 2018

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Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

14 July 2018

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Mitochondrial-nuclear epistasis affects fitness within species but does not contribute to fixed incompatibilities between species of Drosophila

14 July 2018

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Mutation of the mitochondrial tyrosyl-tRNA synthetase gene, YARS2, causes myopathy, lactic acidosis, and sideroblastic anemia--MLASA syndrome

14 July 2018

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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation

14 July 2018

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Interdependence of AMPK and SIRT1 for metabolic adaptation to fasting and exercise in skeletal muscle

14 July 2018

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SRT1720, SRT2183, SRT1460, and resveratrol are not direct activators of SIRT1

14 July 2018

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Perturbation of mitochondrial complex V alters the response to dietary restriction in Drosophila

14 July 2018

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Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

14 July 2018

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4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila

14 July 2018

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The coordination of nuclear and mitochondrial communication during aging and calorie restriction

14 July 2018

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PGC-1alpha, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

14 July 2018

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Effect of a standardised dietary restriction protocol on multiple laboratory strains of Drosophila melanogaster.

14 July 2018

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Sir2 mediates apoptosis through JNK-dependent pathways in Drosophila

14 July 2018

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Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Lifespan and reproduction in Drosophila: New insights from nutritional geometry.

14 July 2018

1 reference

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Mitochondria--a nexus for aging, calorie restriction, and sirtuins?

14 July 2018

1 reference

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Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans

14 July 2018

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Using FlyAtlas to identify better Drosophila melanogaster models of human disease

14 July 2018

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Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Growing roles for the mTOR pathway

14 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Nuclear-mitochondrial epistasis and drosophila aging: introgression of Drosophila simulans mtDNA modifies longevity in D. melanogaster nuclear backgrounds

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Calories do not explain extension of life span by dietary restriction in Drosophila

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways

14 July 2018

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Calorie restriction--the SIR2 connection

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The plasticity of aging: insights from long-lived mutants

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

High absorption but very low bioavailability of oral resveratrol in humans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

mTOR integrates amino acid- and energy-sensing pathways

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The Drosophila melanogaster sir2+ gene is nonessential and has only minor effects on position-effect variegation.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The endocrine regulation of aging by insulin-like signals

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

A Drosophila homologue of Sir2 modifies position-effect variegation but does not affect life span

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Mechanisms of ageing: public or private?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

What regulates mitochondrial DNA copy number in animal cells?

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Estimation of multivariate frailty models using penalized partial likelihood

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Comparative genomics of mitochondrial DNA in Drosophila simulans

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Comparative genomics of mitochondrial DNA in members of the Drosophila melanogaster subgroup.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Sir2 links chromatin silencing, metabolism, and aging

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Dealing with energy demand: the AMP-activated protein kinase

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The mitochondrial genome: structure, transcription, translation and replication

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Female fitness in Drosophila melanogaster: an interaction between the effect of nutrition and of encounter rate with males.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The retardation of aging in mice by dietary restriction: longevity, cancer, immunity and lifetime energy intake

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Identification of point mutations by mispairing PCR as exemplified in MERRF disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

The Journal of Nutrition. Volume 18 July--December, 1939. Pages 1--13. Retarded growth, life span, ultimate body size and age changes in the albino rat after feeding diets restricted in calories

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4022469

Behavioral, physical, and demographic changes in Drosophila populations through dietary restriction.

14 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004354

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004354

Restriction of amino acids extends lifespan in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004354

DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PGEN.1004354

A novel mutation in the mitochondrial tRNA(TYr) gene associated with exercise intolerance

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24832080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Role of NAD(+) in the deacetylase activity of the SIR2-like proteins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24832080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

CPEO associated with a single nucleotide deletion in the mitochondrial tRNA(Tyr) gene

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24832080

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PGEN.1004354

1 reference

28 July 2017

1 reference

28 July 2017

1 reference