(Q33621459)

28 July 2017

title

Fully automated continuous flow synthesis of highly functionalized imidazo[1,2-a] heterocycles (English)

1 reference

28 July 2017

1 reference

Ananda Herath

1

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28 July 2017

Russell Dahl

series ordinal

2

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28 July 2017

Nicholas D P Cosford

series ordinal

3

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28 July 2017

language of work or name

English

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publication date

1 February 2010

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28 July 2017

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28 July 2017

volume

12

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28 July 2017

issue

3

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28 July 2017

page(s)

412-415

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Arylcarboxyamino-substituted diaryl ureas as potent and selective FLT3 inhibitors

28 July 2017

cites work

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Rapid multistep synthesis of 1,2,4-oxadiazoles in a single continuous microreactor sequence

21 June 2018

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High-efficiency aminocarbonylation by introducing CO to a pressurized continuous flow reactor

21 June 2018

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Microfluidics for drug discovery and development: from target selection to product lifecycle management

21 June 2018

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Diversification of the three-component coupling of 2-aminoheterocycles, aldehydes, and isonitriles: efficient parallel synthesis of a diverse and druglike library of imidazo- and tetrahydroimidazo[1,2-a] heterocycles

21 June 2018

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Tools for efficient high-throughput synthesis

21 June 2018

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Greener approaches to organic synthesis using microreactor technology

21 June 2018

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Fully automated flow-through synthesis of secondary sulfonamides in a binary reactor system

21 June 2018

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Micro reactors: a new tool for the synthetic chemist

21 June 2018

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Fully automated continuous flow synthesis of 4,5-disubstituted oxazoles.

21 June 2018

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Chemistry. The future of organic synthesis

21 June 2018

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2-[(4-phenylpiperazin-1-yl)methyl]imidazo(di)azines as selective D4-ligands. Induction of penile erection by 2-[4-(2-methoxyphenyl)piperazin-1-ylmethyl]imidazo[1,2-a]pyridine (PIP3EA), a potent and selective D4 partial agonist

21 June 2018

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Knowledge-based design of target-focused libraries using protein-ligand interaction constraints

21 June 2018

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The impact of microwave synthesis on drug discovery.

21 June 2018

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A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents.

21 June 2018

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Navigating chemical space for biology and medicine

21 June 2018

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Exploring biology with small organic molecules

21 June 2018

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Chemistry in microstructured reactors

21 June 2018

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Continuous flow techniques in organic synthesis

21 June 2018

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Functionalized Polymers-Emerging Versatile Tools for Solution-Phase Chemistry and Automated Parallel Synthesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Efficient syntheses of imidazolo[1,2-a]pyridines and -[2, 1-a]isoquinolines

21 June 2018

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Target-oriented and diversity-oriented organic synthesis in drug discovery

21 June 2018

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2-Amino-3-substituted-6-[(E)-1-phenyl-2-(N-methylcarbamoyl)vinyl]imid azo[1,2-a]pyridines as a novel class of inhibitors of human rhinovirus: stereospecific synthesis and antiviral activity

21 June 2018

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Synthesis of imidazo[1,2-a]pyridines as antiviral agents

21 June 2018

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5-(2-Pyrimidinyl)-imidazo[1,2-a]pyridines are antibacterial agents targeting the ATPase domains of DNA gyrase and topoisomerase IV.

21 June 2018

1 reference

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Multistep synthesis using modular flow reactors: Bestmann-Ohira reagent for the formation of alkynes and triazoles.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Fluorination reactions in microreactors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Flash chemistry: fast chemical synthesis by using microreactors

30 October 2018

1 reference

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Azide monoliths as convenient flow reactors for efficient Curtius rearrangement reactions

30 October 2018

1 reference

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A modular flow reactor for performing Curtius rearrangements as a continuous flow process

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Trimethylaluminium mediated amide bond formation in a continuous flow microreactor as key to the synthesis of rimonabant and efaproxiral

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Multistep continuous-flow microchemical synthesis involving multiple reactions and separations.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Oligosaccharide synthesis in microreactors.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Generation and reactions of o-bromophenyllithium without benzyne formation using a microreactor.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Combining enabling techniques in organic synthesis: continuous flow processes with heterogenized catalysts.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Pharmacological evaluation of an [(123)I] labelled imidazopyridine-3-acetamide for the study of benzodiazepine receptors

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Multistep synthesis of a radiolabeled imaging probe using integrated microfluidics

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

DNA binding ligands targeting drug-resistant bacteria: structure, activity, and pharmacology

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Regiospecific synthesis of 3-substituted imidazo[1,2-a]pyridines, imidazo[1,2-a]pyrimidines, and imidazo[1,2-c]pyrimidine

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

A novel class of orally active non-peptide bradykinin B2 receptor antagonists. 1. Construction of the basic framework

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

Synthesis and oral antiallergic activity of carboxylic acids derived from imidazo[2,1-c][1,4]benzoxazines, imidazo[1,2-a]quinolines, imidazo[1,2-a]quinoxalines, imidazo[1,2-a]quinoxalinones, pyrrolo[1,2-a]quinoxalinones, pyrrolo[2,3-a]quinoxalinones

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2814065

A novel series of imidazo[1,2-a]pyridine derivatives as HIF-1alpha prolyl hydroxylase inhibitors

30 October 2018

1 reference

12 December 2020

New Synthetic Technology for the Rapid Construction of Novel Heterocycles-Part 1: The Reaction of Dess - Martin Periodinane with Anilides and Related Compounds

1 reference

12 December 2020

DERIVATIVES OF IMIDAZOLE. I. SYNTHESIS AND REACTIONS OF IMIDAZO(1,2-A)PYRIDINES WITH ANALGESIC, ANTI-INFLAMMATORY, ANTIPYRETIC, AND ANTICONVULSANT ACTIVITY

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12 December 2020

Chemical space and biology

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12 December 2020

A flow reactor process for the synthesis of peptides utilizing immobilized reagents, scavengers and catch and release protocols

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12 December 2020

New Synthetic Technology for the Rapid Construction of Novel Heterocycles-Part 2. The Reaction of IBX with Anilides and Related Compounds

1 reference

12 December 2020

A Highly Efficient and Convergent Reaction for the Synthesis of Bridgehead Enone-Containing Polycyclic Ring Systems Financial support from the NIH (GM59403-01A1), Bristol-Myers Squibb, Merck Research Laboratories, Pharmacia & Upjohn, Smith-Kline Bee

1 reference

12 December 2020

Spurring radical reactions of organic halides with tin hydride and TTMSS using microreactors

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12 December 2020

New opportunities with the Duff reaction

1 reference

12 December 2020

Identifiers

DOI

10.1021/OL902433A

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28 July 2017

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28 July 2017

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