(Q33621880)

English

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors.

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scholarly article

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20591134%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

A gene expression signature of RAS pathway dependence predicts response to PI3K and RAS pathway inhibitors and expands the population of RAS pathway activated tumors (English)

1 reference

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6 February 2020

Jannik N Andersen

11

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6 February 2020

author name string

Andrey Loboda

1

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6 February 2020

Michael Nebozhyn

2

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6 February 2020

Rich Klinghoffer

3

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6 February 2020

Jason Frazier

4

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6 February 2020

Michael Chastain

5

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6 February 2020

William Arthur

6

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6 February 2020

Brian Roberts

7

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6 February 2020

Theresa Zhang

8

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6 February 2020

Melissa Chenard

9

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6 February 2020

Brian Haines

10

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6 February 2020

Kumiko Nagashima

12

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6 February 2020

Cloud Paweletz

13

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6 February 2020

Bethany Lynch

14

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6 February 2020

Igor Feldman

15

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6 February 2020

Hongyue Dai

16

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6 February 2020

Pearl Huang

17

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6 February 2020

James Watters

18

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6 February 2020

publication date

30 June 2010

1 reference

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6 February 2020

BMC Medical Genomics

1 reference

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6 February 2020

3

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6 February 2020

26

1 reference

Europe PubMed Central

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6 February 2020

https://scigraph.springernature.com/pub.10.1186/1755-8794-3-26

0 references

The PI3K pathway as drug target in human cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Impact of epidermal growth factor receptor and KRAS mutations on clinical outcomes in previously untreated non-small cell lung cancer patients: results of an online tumor registry of clinical trials

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Ras signaling and therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

A genomic strategy to elucidate modules of oncogenic pathway signaling networks

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Singular value decomposition-based regression identifies activation of endogenous signaling pathways in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

K-ras mutations and benefit from cetuximab in advanced colorectal cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Assessment of somatic k-RAS mutations as a mechanism associated with resistance to EGFR-targeted agents: a systematic review and meta-analysis of studies in advanced non-small-cell lung cancer and metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Wild-type KRAS is required for panitumumab efficacy in patients with metastatic colorectal cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Cross platform microarray analysis for robust identification of differentially expressed genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Gene expression signature of human cancer cell lines treated with the ras inhibitor salirasib (S-farnesylthiosalicylic acid).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Genomic signatures to guide the use of chemotherapeutics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Strategies for comparing gene expression profiles from different microarray platforms: application to a case-control experiment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Targeting the mitogen-activated protein kinase pathway in the treatment of malignant melanoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Gene expression profiling in breast cancer: understanding the molecular basis of histologic grade to improve prognosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Oncogenic pathway signatures in human cancers as a guide to targeted therapies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Cross-platform analysis of cancer microarray data improves gene expression based classification of phenotypes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Targeting RAS signalling pathways in cancer therapy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Reverse phase protein microarrays which capture disease progression show activation of pro-survival pathways at the cancer invasion front

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

21 June 2018

Biomarker discovery: identification of a growth factor gene signature

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-3-26

21 January 2018

An oncogenic KRAS2 expression signature identified by cross-species gene-expression analysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2911390

30 October 2018

High-throughput oncogene mutation profiling in human cancer

1 reference

https://api.crossref.org/works/10.1186%2F1755-8794-3-26

21 January 2018

Expression of epiregulin and amphiregulin and K-ras mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab

1 reference

https://pubmed.ncbi.nlm.nih.gov/20591134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

High-resolution genomic and expression analyses of copy number alterations in breast tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/20591134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The most important news at ASCO 2009

1 reference

https://pubmed.ncbi.nlm.nih.gov/20591134

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

RETRACTED: A genomic approach to colon cancer risk stratification yields biologic insights into therapeutic opportunities

1 reference

30 December 2023

https://opencitations.net/index/api/v1/citations/10.1073/PNAS.0806674105

Identifiers

10.1186/1755-8794-3-26

1 reference

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6 February 2020

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1 reference

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6 February 2020

1 reference

Europe PubMed Central

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6 February 2020

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