(Q33626361)

28 July 2017

title

The expression of sphingosine kinase-1 in head and neck carcinoma (English)

1 reference

28 July 2017

main subject

head and neck carcinoma

1 reference

María M Facchinetti

1

1 reference

28 July 2017

Norberto A Gandini

2

1 reference

28 July 2017

María E Fermento

3

1 reference

28 July 2017

Norma B Sterin-Speziale

4

1 reference

28 July 2017

Youngmi Ji

5

1 reference

28 July 2017

Vyomesh Patel

6

1 reference

28 July 2017

J Silvio Gutkind

7

1 reference

28 July 2017

Maria G Rivadulla

8

1 reference

28 July 2017

Alejandro C Curino

9

1 reference

28 July 2017

language of work or name

1 reference

2 July 2010

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28 July 2017

1 reference

28 July 2017

volume

192

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28 July 2017

issue

5

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28 July 2017

page(s)

314-324

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Regulation of histone acetylation in the nucleus by sphingosine-1-phosphate.

28 July 2017

cites work

1 reference

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Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.

21 June 2018

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Targeting SphK1 as a new strategy against cancer

21 June 2018

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The role of sphingosine kinase 1 in cancer: oncogene or non-oncogene addiction?

21 June 2018

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Sphingosine kinases and sphingosine-1-phosphate are critical for transforming growth factor beta-induced extracellular signal-regulated kinase 1 and 2 activation and promotion of migration and invasion of esophageal cancer cells

21 June 2018

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K6PC-5, a direct activator of sphingosine kinase 1, promotes epidermal differentiation through intracellular Ca2+ signaling.

21 June 2018

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Principles of bioactive lipid signalling: lessons from sphingolipids

21 June 2018

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Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

21 June 2018

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21 June 2018

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Involvement of sphingosine kinase 2 in p53-independent induction of p21 by the chemotherapeutic drug doxorubicin

21 June 2018

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Autocrine and paracrine roles of sphingosine-1-phosphate

21 June 2018

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Dissecting the Akt/mammalian target of rapamycin signaling network: emerging results from the head and neck cancer tissue array initiative.

21 June 2018

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Clinical relevance of ceramide metabolism in the pathogenesis of human head and neck squamous cell carcinoma (HNSCC): attenuation of C(18)-ceramide in HNSCC tumors correlates with lymphovascular invasion and nodal metastasis

21 June 2018

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ECTO-NOX target for the anticancer isoflavene phenoxodiol.

21 June 2018

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21 June 2018

Cancer statistics, 2007

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Functions of the multifaceted family of sphingosine kinases and some close relatives

21 June 2018

1 reference

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Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

21 June 2018

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Intracellular role for sphingosine kinase 1 in intestinal adenoma cell proliferation

21 June 2018

1 reference

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Spotlight on tNOX: a tumor-selective target for cancer therapies

21 June 2018

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Enhancement of SPHK1 in vitro by carbon ion irradiation in oral squamous cell carcinoma

21 June 2018

1 reference

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Antitumor activity of sphingosine kinase inhibitors

21 June 2018

1 reference

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Sphingosine kinase: biochemical and cellular regulation and role in disease

21 June 2018

1 reference

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Sphingosine kinase 1 is up-regulated in colon carcinogenesis

21 June 2018

1 reference

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Sphingosine kinase-1 expression correlates with poor survival of patients with glioblastoma multiforme: roles of sphingosine kinase isoforms in growth of glioblastoma cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1.

21 June 2018

1 reference

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The complex life of simple sphingolipids

21 June 2018

1 reference

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UCN-01-induced cell cycle arrest requires the transcriptional induction of p21(waf1/cip1) by activation of mitogen-activated protein/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase pathway

21 June 2018

1 reference

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Down-regulation of sphingosine kinase-1 by DNA damage: dependence on proteases and p53.

21 June 2018

1 reference

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Sphingosine kinase type 2 is a putative BH3-only protein that induces apoptosis

21 June 2018

1 reference

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Phenoxodiol – an isoflavone analog – induces apoptosis in chemoresistant ovarian cancer cells

21 June 2018

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Signaling and biological actions of sphingosine 1-phosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Sphingosine-1-phosphate and its potentially paradoxical effects on critical parameters of cutaneous wound healing

21 June 2018

1 reference

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Killing tumours by ceramide-induced apoptosis: a critique of available drugs

21 June 2018

1 reference

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PKC-dependent activation of sphingosine kinase 1 and translocation to the plasma membrane. Extracellular release of sphingosine-1-phosphate induced by phorbol 12-myristate 13-acetate (PMA)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

1Alpha,25-dihydroxyvitamin D3 protects human keratinocytes from apoptosis by the formation of sphingosine-1-phosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Cell type-specific localization of sphingosine kinase 1a in human tissues

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

C2-ceramide induces apoptosis in a human squamous cell carcinoma cell line

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

An oncogenic role of sphingosine kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Human sphingosine kinase: purification, molecular cloning and characterization of the native and recombinant enzymes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Molecular cloning and functional characterization of a novel mammalian sphingosine kinase type 2 isoform

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Different vitamin D analogues induce sphingomyelin hydrolysis and apoptosis in the human keratinocyte cell line HaCaT

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

High prevalence of p16 genetic alterations in head and neck tumours

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Sphingosine kinase expression increases intracellular sphingosine-1-phosphate and promotes cell growth and survival.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Molecular cloning and functional characterization of murine sphingosine kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Topoisomerase II: A specific marker for cell proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Inhibitory effects of the tyrosine kinase inhibitor genistein on mammalian DNA topoisomerase II

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Stratification of sphingosine kinase-1 expression and activity in rat kidney

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Sphingosine 1-phosphate restrains insulin-mediated keratinocyte proliferation via inhibition of Akt through the S1P2 receptor subtype

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

The antiproliferative effects of phenoxodiol are associated with inhibition of plasma membrane electron transport in tumour cell lines and primary immune cells.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Cell cycle regulating proteins p21 and p27 in prognosis of oral squamous cell carcinomas.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Phenoxodiol, an experimental anticancer drug, shows potent antiangiogenic properties in addition to its antitumour effects

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Immunohistochemical distribution of sphingosine kinase 1 in normal and tumor lung tissue

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Glucocorticoids mediate differential anti-apoptotic effects in human fibroblasts and keratinocytes via sphingosine-1-phosphate formation

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Sphingosine kinase 2 is a nuclear protein and inhibits DNA synthesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Human papillomavirus positivity predicts favourable outcome for squamous carcinoma of the tonsil

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

p53, p21 and p27 protein expression in head and neck cancer and their prognostic value.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2974839

Identification in human urine of a natural growth inhibitor for cells derived from solid paediatric tumours

30 October 2018

1 reference

12 December 2020

Molecular analysis of p53 gene in laryngeal premalignant and malignant lesions. p53 protein immunohistochemical expression is positively related to proliferating cell nuclear antigen labelling index

1 reference

12 December 2020

Interaction between bcl-2 and p21 (WAF1/CIP1) in breast carcinomas with wild-type p53

1 reference

12 December 2020

Prognostic significance of p21WAF1/CIP1 expression in tongue squamous cell carcinomas

1 reference

12 December 2020

Identifiers

DOI

10.1159/000318173

1 reference

28 July 2017

1 reference

28 July 2017

1 reference