(Q33627407)

28 July 2017

Moving gating charges through the gating pore in a Kv channel voltage sensor (English)

1 reference

Fabiana Vasconcelos Campos

28 July 2017

0 references

object named as

Fabiana V Campos

3

0 references

author name string

Jérôme J Lacroix

1

1 reference

28 July 2017

H Clark Hyde

2

1 reference

28 July 2017

Francisco Bezanilla

4

1 reference

28 July 2017

language of work or name

English

0 references

publication date

29 April 2014

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

1 reference

28 July 2017

111

1 reference

28 July 2017

19

1 reference

28 July 2017

E1950-9

1 reference

Hydrophobic plug functions as a gate in voltage-gated proton channels

28 July 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Hydrogen bonds as molecular timers for slow inactivation in voltage-gated potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

The gating charge should not be estimated by fitting a two-state model to a Q-V curve

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Molecular bases for the asynchronous activation of sodium and potassium channels required for nerve impulse generation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Proton channel HVCN1 is required for effector functions of mouse eosinophils

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

The conserved phenylalanine in the K+ channel voltage-sensor domain creates a barrier with unidirectional effects

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Intermediate state trapping of a voltage sensor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

An emerging consensus on voltage-dependent gating from computational modeling and molecular dynamics simulations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Identification of SCN1A and PCDH19 mutations in Chinese children with Dravet syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Mechanism of voltage gating in potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

In search of a consensus model of the resting state of a voltage-sensing domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Do Hv1 proton channels regulate the ionic and redox homeostasis of phagosomes?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

R1 in the Shaker S4 occupies the gating charge transfer center in the resting state

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Contributions of counter-charge in a potassium channel voltage-sensor domain.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Control of a final gating charge transition by a hydrophobic residue in the S2 segment of a K+ channel voltage sensor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Properties of deactivation gating currents in Shaker channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Salt bridges: geometrically specific, designable interactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Calculation of the gating charge for the Kv1.2 voltage-activated potassium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A Gating Charge Transfer Center in Voltage Sensors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

An intersubunit interaction between S4-S5 linker and S6 is responsible for the slow off-gating component in Shaker K+ channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Molecular determinants of coupling between the domain III voltage sensor and pore of a sodium channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A role of SCN9A in human epilepsies, as a cause of febrile seizures and as a potential modifier of Dravet syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Hyperpolarization-activated cation channels: from genes to function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A novel dominant mutation of the Nav1.4 alpha-subunit domain I leading to sodium channel myotonia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A common pathway for charge transport through voltage-sensing domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Atomic structure of a voltage-dependent K+ channel in a lipid membrane-like environment

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Two atomic constraints unambiguously position the S4 segment relative to S1 and S2 segments in the closed state of Shaker K channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A voltage sensor-domain protein is a voltage-gated proton channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A voltage-gated proton-selective channel lacking the pore domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Crystal structure of a mammalian voltage-dependent Shaker family K+ channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Recognition of transmembrane helices by the endoplasmic reticulum translocon.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A quantitative description of membrane current and its application to conduction and excitation in nerve

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Mutations of sodium channel alpha subunit type 1 (SCN1A) in intractable childhood epilepsies with frequent generalized tonic-clonic seizures

21 June 2018

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

21 June 2018

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Scanning the intracellular S6 activation gate in the shaker K+ channel

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Allelic variants in long-QT disease genes in patients with drug-associated torsades de pointes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Histidine scanning mutagenesis of basic residues of the S4 segment of the shaker k+ channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Electrostatics and the gating pore of Shaker potassium channels

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A localized interaction surface for voltage-sensing domains on the pore domain of a K+ channel.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

alpha-helical structural elements within the voltage-sensing domains of a K(+) channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Mutations in the S4 region isolate the final voltage-dependent cooperative step in potassium channel activation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Cut-open oocyte voltage-clamp technique

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

How does the W434F mutation block current in Shaker potassium channels?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Mapping the receptor site for hanatoxin, a gating modifier of voltage-dependent K+ channels.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Episodic ataxia results from voltage-dependent potassium channels with altered functions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Experimentally determined hydrophobicity scale for proteins at membrane interfaces

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Contribution of the S4 segment to gating charge in the Shaker K+ channel.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Identification of two new KCNA1 mutations in episodic ataxia/myokymia families

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

A simple method for displaying the hydropathic character of a protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Interior and surface of monomeric proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Alteration of voltage-dependence of Shaker potassium channel by mutations in the S4 sequence

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4024920

Movement of 'gating charge' is coupled to ligand binding in a G-protein-coupled receptor.

21 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Calcium-activated and voltage-gated potassium channels of the pancreatic islet impart distinct and complementary roles during secretagogue induced electrical responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Voltage-sensing residues in the S2 and S4 segments of the Shaker K+ channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

A proton pore in a potassium channel voltage sensor reveals a focused electric field

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Focused electric field across the voltage sensor of potassium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

A fluorometric approach to local electric field measurements in a voltage-gated ion channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Episodic ataxia type 1 mutations in the KCNA1 gene impair the fast inactivation properties of the human potassium channels Kv1.4-1.1/Kvbeta1.1 and Kv1.4-1.1/Kvbeta1.2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Characterization of the Kv1.1 I262T and S342I mutations associated with episodic ataxia 1 with distinct phenotypes

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Functional interactions at the interface between voltage-sensing and pore domains in the Shaker K(v) channel.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Ile-177 and Ser-180 in the S1 segment are critically important in Kv1.1 channel function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Gating currents from a nonconducting mutant reveal open-closed conformations in Shaker K+ channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Tuning the voltage-sensor motion with a single residue

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1406161111

Energetics of pore opening in a voltage-gated K(+) channel

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24782544

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetic variations of KCNQ1, KCNH2, SCN5A, KCNE1, and KCNE2 in drug-induced long QT syndrome patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24782544

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1406161111

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference