(Q33628891)

28 July 2017

title

O-linked N-acetylglucosamine modification of insulin receptor substrate-1 occurs in close proximity to multiple SH2 domain binding motifs (English)

1 reference

28 July 2017

1 reference

Lauren E Ball

1 reference

28 July 2017

Amanda L Klein

1

1 reference

28 July 2017

Mary N Berkaw

series ordinal

2

1 reference

28 July 2017

Maria G Buse

series ordinal

3

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28 July 2017

publication date

11 August 2009

1 reference

Molecular & Cellular Proteomics

28 July 2017

published in

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28 July 2017

volume

8

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28 July 2017

issue

12

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28 July 2017

page(s)

2733-2745

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Insulin receptor substrates (IRSs) and breast tumorigenesis

28 July 2017

cites work

1 reference

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21 June 2018

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Phosphorylation of human insulin receptor substrate-1 at Serine 629 plays a positive role in insulin signaling

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Chronic hexosamine flux stimulates fatty acid oxidation by activating AMP-activated protein kinase in adipocytes.

21 June 2018

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Mammary tumorigenesis and metastasis caused by overexpression of insulin receptor substrate 1 (IRS-1) or IRS-2

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Suppression of insulin receptor substrate 1 (IRS-1) promotes mammary tumor metastasis

21 June 2018

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21 June 2018

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Identification of the major site of O-linked beta-N-acetylglucosamine modification in the C terminus of insulin receptor substrate-1.

21 June 2018

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Identification of insulin receptor substrate 1 serine/threonine phosphorylation sites using mass spectrometry analysis: regulatory role of serine 1223.

21 June 2018

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O-GlcNAc modification on IRS-1 and Akt2 by PUGNAc inhibits their phosphorylation and induces insulin resistance in rat primary adipocytes

21 June 2018

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Comprehensive analysis of a multidimensional liquid chromatography mass spectrometry dataset acquired on a quadrupole selecting, quadrupole collision cell, time-of-flight mass spectrometer: II. New developments in Protein Prospector allow for reliab

21 June 2018

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21 June 2018

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The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

21 June 2018

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21 June 2018

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Insulin-dependent activation of endothelial nitric oxide synthase is impaired by O-linked glycosylation modification of signaling proteins in human coronary endothelial cells

21 June 2018

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Elevated nucleocytoplasmic glycosylation by O-GlcNAc results in insulin resistance associated with defects in Akt activation in 3T3-L1 adipocytes

21 June 2018

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Dynamic O-glycosylation of nuclear and cytosolic proteins: cloning and characterization of a neutral, cytosolic beta-N-acetylglucosaminidase from human brain

21 June 2018

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The Gly-->Arg972 amino acid polymorphism in insulin receptor substrate-1 affects glucose metabolism in skeletal muscle cells

21 June 2018

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The COOH-terminal tyrosine phosphorylation sites on IRS-1 bind SHP-2 and negatively regulate insulin signaling

21 June 2018

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21 June 2018

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The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling

21 June 2018

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Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1

21 June 2018

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Glycosylation of nuclear and cytoplasmic proteins. Purification and characterization of a uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylglucosaminyltransferase

21 June 2018

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Reduced activation of phosphatidylinositol-3 kinase and increased serine 636 phosphorylation of insulin receptor substrate-1 in primary culture of skeletal muscle cells from patients with type 2 diabetes

21 June 2018

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Increased O-glycosylation of insulin signaling proteins results in their impaired activation and enhanced susceptibility to apoptosis in pancreatic beta-cells

21 January 2018

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Activation of the hexosamine pathway leads to phosphorylation of insulin receptor substrate-1 on Ser307 and Ser612 and impairs the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin insulin biosynthetic pathway in RIN pancreatic beta-ce

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900207-MCP200

Human insulin receptor substrate-1 (IRS-1) polymorphism G972R causes IRS-1 to associate with the insulin receptor and inhibit receptor autophosphorylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900207-MCP200

Characterization of a mouse monoclonal antibody specific for O-linked N-acetylglucosamine

21 January 2018

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A new approach for sequencing human IRS1 phosphotyrosine-containing peptides using CapLC-Q-TOF(micro).

21 January 2018

1 reference

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Global Assessment of Regulation of Phosphorylation of Insulin Receptor Substrate-1 by Insulin In Vivo in Human Muscle

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FMCP.M900207-MCP200

Activation of cJun NH2-terminal kinase/stress-activated protein kinase by insulin

21 January 2018

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12 December 2020

Novel allele of the insulin receptor substrate-1 bearing two non-conservative amino acid substitutions in a patient with noninsulin-dependent diabetes mellitus. Mutations in brief no. 130. Online

1 reference

12 December 2020

Activation of the hexosamine pathway by glucosamine in vivo induces insulin resistance of early postreceptor insulin signaling events in skeletal muscle

1 reference

12 December 2020

Phosphorylation of insulin receptor substrate-1 (IRS-1) by protein kinase B positively regulates IRS-1 function

1 reference

12 December 2020

10.1074/MCP.M900207-MCP200

Identifiers

DOI

1 reference

28 July 2017

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28 July 2017

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