(Q33632804)

28 July 2017

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title

The biochemical basis of arsenical-diamidine crossresistance in African trypanosomes (English)

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28 July 2017

Fairlamb AH

2

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Michael P. Barrett

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author name string

Barrett MP

series ordinal

1

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28 July 2017

publication date

1 April 1999

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28 July 2017

published in

Trends in Parasitology

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28 July 2017

volume

15

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28 July 2017

issue

4

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28 July 2017

page(s)

136-140

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The treatment of human African trypanosomiasis

28 July 2017

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Differential susceptibility to DL-alpha-difluoromethylornithine in clinical isolates of Trypanosoma brucei rhodesiense

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7 January 2021

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7 January 2021

Risk factors for encephalopathy and mortality during melarsoprol treatment of Trypanosoma brucei gambiense sleeping sickness

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7 January 2021

Properties of melarsamine hydrochloride (Cymelarsan) in aqueous solution.

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7 January 2021

Effects of various metabolic conditions and of the trivalent arsenical melarsen oxide on the intracellular levels of fructose 2,6-bisphosphate and of glycolytic intermediates in Trypanosoma brucei.

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7 January 2021

Trypanothione is the primary target for arsenical drugs against African trypanosomes

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7 January 2021

The interaction of arsenical drugs with dihydrolipoamide and dihydrolipoamide dehydrogenase from arsenical resistant and sensitive strains of Trypanosoma brucei brucei

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7 January 2021

Mechanism of inhibition of trypanothione reductase and glutathione reductase by trivalent organic arsenicals

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7 January 2021

Pharmacology of diminazene: a review

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7 January 2021

Inhibition of topoisomerases in African trypanosomes

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7 January 2021

A calmodulin-stimulated Ca2+ pump in plasma-membrane vesicles from Trypanosoma brucei; selective inhibition by pentamidine

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7 January 2021

Characterization of Trypanosoma brucei brucei S-adenosyl-L-methionine decarboxylase and its inhibition by Berenil, pentamidine and methylglyoxal bis(guanylhydrazone).

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7 January 2021

Polyamine and pentamidine metabolism in African trypanosomes

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7 January 2021

Pentamidine transport in Trypanosoma brucei—Kinetics and specificity

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7 January 2021

Characterisation of pentamidine-resistant Trypanosoma brucei brucei

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7 January 2021

Uptake of diamidine drugs by the P2 nucleoside transporter in melarsen-sensitive and -resistant Trypanosoma brucei brucei

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7 January 2021

In vivo and in vitro sensitivity of Trypanosoma evansi and T. equiperdum to diminazene, suramin, MelCy, quinapyramine and isometamidium

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7 January 2021

Characterisation of melarsen-resistant Trypanosoma brucei brucei with respect to cross-resistance to other drugs and trypanothione metabolism

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7 January 2021

Trypanosoma evansi: in vivo and in vitro determination of trypanocide resistance profiles.

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7 January 2021

Induction of resistance to melarsenoxide cysteamine (Mel Cy) in Trypanosoma brucei brucei

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7 January 2021

Alteration to one of three adenosine transporters is associated with resistance to cymelarsan in Trypanosoma evansi

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7 January 2021

Trypanosoma brucei: lack of cross-resistance to melarsoprol in vitro by cymelarsan-resistant parasites

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7 January 2021

Analysis of the Trypanocidal Action of Trivalent Arsenicals and Acriflavine

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7 January 2021

Heme lysis of the bloodstream forms of Trypanosoma brucei

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7 January 2021

Arsenical-resistant trypanosomes lack an unusual adenosine transporter

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7 January 2021

A diamidine-resistant Trypanosoma equiperdum clone contains a P2 purine transporter with reduced substrate affinity.

1 reference

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7 January 2021

Characterisation of cloned lines of Trypanosoma brucei expressing stable resistance to MelCy and suramin

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7 January 2021

Biochemistry of multidrug resistance mediated by the multidrug transporter

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7 January 2021

New mechanisms of drug resistance in parasitic protozoa

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7 January 2021

Multidrug resistance and P-glycoproteins in parasitic protozoa.

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7 January 2021

Molecular characterization of a P-glycoprotein-related tcpgp2 gene in Trypanosoma cruzi.

1 reference

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7 January 2021

High level arsenite resistance in Leishmania tarentolae is mediated by an active extrusion system.

1 reference

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7 January 2021

Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania

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7 January 2021

Efflux systems and increased trypanothione levels in arsenite-resistant Leishmania

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7 January 2021

An ATP-dependent As(III)-glutathione transport system in membrane vesicles of Leishmania tarentolae

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7 January 2021

Differential sensitivity of Trypanosoma brucei rhodesiense isolates to in vitro lysis by arsenicals.

1 reference

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7 January 2021

Purine nucleobase transport in bloodstream forms of Trypanosoma brucei brucei is mediated by two novel transporters

1 reference

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7 January 2021

An approach to use an unusual adenosine transporter to selectively deliver polyamine analogues to trypanosomes

1 reference

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7 January 2021

10.1016/S0169-4758(99)01414-3

Identifiers

DOI

1 reference

release_4uk5anuoufbadi2bjyohzunsvq

28 July 2017

Fatcat ID

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Fatcat

https://api.fatcat.wiki/v0/release/4uk5anuoufbadi2bjyohzunsvq

24 November 2022

mapped directly with Wikidata item

1 reference