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PINK1 is degraded through the N-end rule pathway
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scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
title
PINK1 is degraded through the N-end rule pathway
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
author
Richard J. Youle
series ordinal
2
object named as
Richard J Youle
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
author name string
Koji Yamano
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
publication date
17 April 2013
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
published in
Autophagy
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
volume
9
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
issue
11
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
page(s)
1758-1769
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
cites work
Pink1 kinase and its membrane potential (Deltaψ)-dependent cleavage product both localize to outer mitochondrial membrane by unique targeting mode
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
The N-end rule pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Fumarase: a paradigm of dual targeting and dual localized functions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
A TALE nuclease architecture for efficient genome editing
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
PINK1 cleavage at position A103 by the mitochondrial protease PARL.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Importing mitochondrial proteins: machineries and mechanisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
The kinase domain of mitochondrial PINK1 faces the cytoplasm
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Characterization of PINK1 processing, stability, and subcellular localization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Cytoplasmic localization and proteasomal degradation of N-terminally cleaved form of PINK1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Pink1 Parkinson mutations, the Cdc37/Hsp90 chaperones and Parkin all influence the maturation or subcellular distribution of Pink1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
The mitochondrial protease HtrA2 is regulated by Parkinson's disease-associated kinase PINK1.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
PINK1 protects against oxidative stress by phosphorylating mitochondrial chaperone TRAP1
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Translocation of proteins into mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Drosophila pink1 is required for mitochondrial function and interacts genetically with parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Mitochondrial dysfunction in Drosophila PINK1 mutants is complemented by parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Female Lethality and Apoptosis of Spermatocytes in Mice Lacking the UBR2 Ubiquitin Ligase of the N-End Rule Pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Mitochondrial pathology and apoptotic muscle degeneration in Drosophila parkin mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Unfolding of preproteins upon import into mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Using ubiquitin to follow the metabolic fate of a protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
In vivo half-life of a protein is a function of its amino-terminal residue
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
21 June 2018
Heritable gene targeting in zebrafish using customized TALENs.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
30 October 2018
Step-size analyses of the mitochondrial Hsp70 import motor reveal the Brownian ratchet in operation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
30 October 2018
L347P PINK1 mutant that fails to bind to Hsp90/Cdc37 chaperones is rapidly degraded in a proteasome-dependent manner.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
30 October 2018
Mitochondrial import of Omi: the definitive role of the putative transmembrane region and multiple processing sites in the amino-terminal segment.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
30 October 2018
Ubiquitin fusion technique and related methods
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
30 October 2018
Mitochondrial import and enzymatic activity of PINK1 mutants associated to recessive parkinsonism.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4028335
retrieved
30 October 2018
Identifiers
DOI
10.4161/AUTO.24633
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
PMCID
4028335
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
PubMed ID
24121706
1 reference
stated in
Europe PubMed Central
PubMed ID
24121706
retrieved
28 July 2017
ResearchGate publication ID
257754615
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