(Q33640002)

28 July 2017

title

Activation of mitochondrial ERK protects cancer cells from death through inhibition of the permeability transition (English)

1 reference

28 July 2017

Andrea Rasola

1

1 reference

28 July 2017

Marco Sciacovelli

2

1 reference

28 July 2017

Federica Chiara

3

1 reference

28 July 2017

Boris Pantic

4

1 reference

28 July 2017

William S Brusilow

5

1 reference

28 July 2017

Paolo Bernardi

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

22 December 2009

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

1 reference

28 July 2017

volume

107

1 reference

28 July 2017

issue

2

1 reference

28 July 2017

page(s)

726-731

1 reference

Constitutive ERK MAPK activity regulates macrophage ATP production and mitochondrial integrity

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Role of JNK translocation to mitochondria leading to inhibition of mitochondria bioenergetics in acetaminophen-induced liver injury

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

A mitochondrial kinase complex is essential to mediate an ERK1/2-dependent phosphorylation of a key regulatory protein in steroid biosynthesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

MAP kinase signalling pathways in cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

MAPKs: function, regulation, role in cancer and therapeutic targeting

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Rewired ERK-JNK signaling pathways in melanoma

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Hyperactive Ras in developmental disorders and cancer

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

A novel mitochondrial matrix serine/threonine protein phosphatase regulates the mitochondria permeability transition pore and is essential for cellular survival and development

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial permeability transition pore and its involvement in cell death and in disease pathogenesis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Roles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Mitochondrial hexokinases, novel mediators of the antiapoptotic effects of growth factors and Akt.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial permeability transition from in vitro artifact to disease target

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The reperfusion injury salvage kinase pathway: a common target for both ischemic preconditioning and postconditioning.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Signal transduction in prostate cancer progression

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Glycogen synthase kinase-3beta mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Oxidative neuronal injury. The dark side of ERK1/2.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The glamour and gloom of glycogen synthase kinase-3

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Mitogen-activated protein kinase/extracellular signal-regulated kinase attenuates 3-hydroxykynurenine-induced neuronal cell death

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Localization of phosphorylated ERK/MAP kinases to mitochondria and autophagosomes in Lewy body diseases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

The mitochondrial permeability transition, release of cytochrome c and cell death. Correlation with the duration of pore openings in situ

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Regulation of the permeability transition pore in skeletal muscle mitochondria. Modulation By electron flow through the respiratory chain complex i.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818893

Mitochondrial extracellular signal-regulated kinases 1/2 (ERK1/2) are modulated during brain development

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Arachidonic acid released by phospholipase A(2) activation triggers Ca(2+)-dependent apoptosis through the mitochondrial pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Aggravation of necrotic death of glucose-deprived cells by the MEK1 inhibitors U0126 and PD184161 through depletion of ATP.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Erk associates with and primes GSK-3beta for its inactivation resulting in upregulation of beta-catenin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

A flow cytometry assay simultaneously detects independent apoptotic parameters

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Apoptosis to necrosis switching downstream of apoptosome formation requires inhibition of both glycolysis and oxidative phosphorylation in a BCL-X(L)- and PKB/AKT-independent fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Glycogen synthase kinase-3β mediates convergence of protection signaling to inhibit the mitochondrial permeability transition pore

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0912742107

Modulation of the mitochondrial permeability transition pore complex in GSK-3beta-mediated myocardial protection

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080742

12 December 2020

inferred from PubMed ID database lookup

Translocation of SAPK/JNK to mitochondria and interaction with Bcl-x(L) in response to DNA damage

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080742

12 December 2020

inferred from PubMed ID database lookup

Direct activation of mitochondrial apoptosis machinery by c-Jun N-terminal kinase in adult cardiac myocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080742

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0912742107

1 reference

release_w4rkm66gqjdj7nti42f2eq3hd4

28 July 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/w4rkm66gqjdj7nti42f2eq3hd4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

2818893

1 reference

28 July 2017

1 reference