(Q33234059)

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The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative

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Europe PubMed Central

24 July 2017

The mitochondrial effects of small organic ligands of BCL-2: sensitization of BCL-2-overexpressing cells to apoptosis by a pyrimidine-2,4,6-trione derivative (English)

1 reference

Europe PubMed Central

24 July 2017

1 reference

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Valeria Petronilli

object named as

Valeria Petronilli

5

0 references

object named as

Paolo Bernardi

10

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Gianpietro Semenzato

object named as

Gianpietro Semenzato

7

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author name string

Eva Milanesi

1

1 reference

Europe PubMed Central

24 July 2017

Paola Costantini

2

1 reference

Europe PubMed Central

24 July 2017

Alberto Gambalunga

3

1 reference

Europe PubMed Central

24 July 2017

Raffaele Colonna

4

1 reference

Europe PubMed Central

24 July 2017

Anna Cabrelle

6

1 reference

Europe PubMed Central

24 July 2017

Andrea M Cesura

8

1 reference

Europe PubMed Central

24 July 2017

Emmanuel Pinard

9

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Europe PubMed Central

24 July 2017

language of work or name

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publication date

14 February 2006

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Europe PubMed Central

24 July 2017

Journal of Biological Chemistry

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Europe PubMed Central

24 July 2017

281

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Europe PubMed Central

24 July 2017

15

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Europe PubMed Central

24 July 2017

10066-10072

1 reference

Europe PubMed Central

24 July 2017

Upregulation of Bcl-2 is involved in the mediation of chemotherapy resistance in human small cell lung cancer cell lines

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Apoptosis-based therapies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Death and anti-death: tumour resistance to apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Life-or-death decisions by the Bcl-2 protein family.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Structure-based discovery of an organic compound that binds Bcl-2 protein and induces apoptosis of tumor cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Identification of chelerythrine as an inhibitor of BclXL function

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

A mitochondrial perspective on cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blocked

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Mitochondria and cell death. Mechanistic aspects and methodological issues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

BH3-domain mimetic compound BH3I-2' induces rapid damage to the inner mitochondrial membrane prior to the cytochrome c release from mitochondria.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Interactions of cyclophilin with the mitochondrial inner membrane and regulation of the permeability transition pore, and cyclosporin A-sensitive channel.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Critical upstream signals of cytochrome C release induced by a novel Bcl-2 inhibitor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Bcl-2 inhibitors sensitize tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by uncoupling of mitochondrial respiration in human leukemic CEM cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Early resistance to cell death and to onset of the mitochondrial permeability transition during hepatocarcinogenesis with 2-acetylaminofluorene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Desensitization of the permeability transition pore by cyclosporin a prevents activation of the mitochondrial apoptotic pathway and liver damage by tumor necrosis factor-alpha

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

An inhibitor of Bcl-2 family proteins induces regression of solid tumours

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M513708200

21 January 2018

Identifiers

10.1074/JBC.M513708200

1 reference

Europe PubMed Central

24 July 2017

1 reference

Europe PubMed Central

24 July 2017

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