(Q28217065)

CD95(APO-1/Fas)-mediated apoptosis in normal and malignant liver, colon, and hematopoietic cells

31 March 2020

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CD95(APO-1/Fas)-mediated apoptosis: live and let die

31 March 2020

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Regulation of death receptor-mediated apoptosis pathways

31 March 2020

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Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

31 March 2020

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A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosis

31 March 2020

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FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

31 March 2020

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Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8

31 March 2020

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Two CD95 (APO-1/Fas) signaling pathways

31 March 2020

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The mitochondrion in apoptosis: how Pandora's box opens

31 March 2020

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Breaking the mitochondrial barrier

31 March 2020

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The central effectors of cell death in the immune system

31 March 2020

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Corpse clearance defines the meaning of cell death

31 March 2020

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Apoptosis without caspases: an inefficient molecular guillotine?

31 March 2020

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BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases

31 March 2020

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An alternative, nonapoptotic form of programmed cell death

31 March 2020

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FLICE-inhibitory proteins: regulators of death receptor-mediated apoptosis

31 March 2020

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IAP family proteins--suppressors of apoptosis

31 March 2020

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Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

31 March 2020

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Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

31 March 2020

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Proliferation, cell cycle and apoptosis in cancer

31 March 2020

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Induction of apoptosis in fibroblasts by c-myc protein

31 March 2020

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Apoptotic cell death induced by c-myc is inhibited by bcl-2.

31 March 2020

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c-Myc-induced apoptosis in fibroblasts is inhibited by specific cytokines.

31 March 2020

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Essential role for p53-mediated transcription in E1A-induced apoptosis

31 March 2020

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Modulation of cellular apoptotic potential: contributions to oncogenesis

31 March 2020

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Cellular survival: a play in three Akts

31 March 2020

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31 March 2020

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Disruption of epithelial cell-matrix interactions induces apoptosis

31 March 2020

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Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway

31 March 2020

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The proapoptotic activity of the Bcl-2 family member Bim is regulated by interaction with the dynein motor complex

31 March 2020

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Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis

31 March 2020

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Telomeres, telomerase, and cancer: life on the edge of genomic stability

31 March 2020

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Inhibition of telomerase limits the growth of human cancer cells.

31 March 2020

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Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

31 March 2020

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

31 March 2020

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How do cytotoxic lymphocytes kill their targets?

31 March 2020

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Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

31 March 2020

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

31 March 2020

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Cleavage of FLICE (caspase-8) by granzyme B during cytotoxic T lymphocyte-induced apoptosis

31 March 2020

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Granzyme B-mediated cytochrome c release is regulated by the Bcl-2 family members bid and Bax.

31 March 2020

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Fas involvement in Ca(2+)-independent T cell-mediated cytotoxicity

31 March 2020

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Cellular stress response and apoptosis in cancer therapy.

31 March 2020

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Activation of apoptosis pathways in peripheral blood lymphocytes by in vivo chemotherapy

31 March 2020

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Regulation and function of the p53 tumor suppressor protein

31 March 2020

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The INK4a/ARF network in tumour suppression

31 March 2020

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A novel form of Epstein-Barr virus latency in normal B cells in vivo

31 March 2020

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Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis

31 March 2020

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PUMA, a novel proapoptotic gene, is induced by p53

31 March 2020

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p53AIP1, a potential mediator of p53-dependent apoptosis, and its regulation by Ser-46-phosphorylated p53

31 March 2020

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p53 activates the CD95 (APO-1/Fas) gene in response to DNA damage by anticancer drugs

31 March 2020

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Evidence that the death receptor DR4 is a DNA damage-inducible, p53-regulated gene

31 March 2020

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KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene

31 March 2020

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p53-dependent apoptosis in the absence of transcriptional activation of p53-target genes

31 March 2020

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Apaf-1 and caspase-9 in p53-dependent apoptosis and tumor inhibition.

31 March 2020

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Cell surface trafficking of Fas: a rapid mechanism of p53-mediated apoptosis.

31 March 2020

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Reactive oxygen intermediates are involved in the induction of CD95 ligand mRNA expression by cytostatic drugs in hepatoma cells

31 March 2020

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Involvement of the CD95 (APO–1/Fas) receptor/ligand system in drug–induced apoptosis in leukemia cells

31 March 2020

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Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells.

31 March 2020

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Drug-induced apoptosis in hepatoma cells is mediated by the CD95 (APO-1/Fas) receptor/ligand system and involves activation of wild-type p53.

31 March 2020

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A novel AP-1 element in the CD95 ligand promoter is required for induction of apoptosis in hepatocellular carcinoma cells upon treatment with anticancer drugs

31 March 2020

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Ionizing radiation and chemotherapeutic drugs induce apoptosis in lymphocytes in the absence of Fas or FADD/MORT1 signaling. Implications for cancer therapy

31 March 2020

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FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis

31 March 2020

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Involvement of the bcl-2 gene in human follicular lymphoma

31 March 2020

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bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation

31 March 2020

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Oncogenic potential of bcl-2 demonstrated by gene transfer.

31 March 2020

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Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2.

31 March 2020

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Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

31 March 2020

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BCL-2 cooperates with promyelocytic leukemia retinoic acid receptor alpha chimeric protein (PMLRARalpha) to block neutrophil differentiation and initiate acute leukemia

31 March 2020

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Protooncogene bcl-2 gene transfer abrogates Fas/APO-1 antibody-mediated apoptosis of human malignant glioma cells and confers resistance to chemotherapeutic drugs and therapeutic irradiation

31 March 2020

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Genetic analysis of chemoresistance in primary murine lymphomas.

31 March 2020

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Epstein-Barr virus-coded BHRF1 protein, a viral homologue of Bcl-2, protects human B cells from programmed cell death

31 March 2020

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Epstein-Barr virus BHRF1 protein protects against cell death induced by DNA-damaging agents and heterologous viral infection

31 March 2020

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Kaposi's sarcoma-associated herpesvirus encodes a functional Bcl-2 homologue

31 March 2020

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

31 March 2020

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Drug resistance of human glioblastoma cells conferred by a tumor-specific mutant epidermal growth factor receptor through modulation of Bcl-XL and caspase-3-like proteases

31 March 2020

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Inhibition of death receptor signals by cellular FLIP

31 March 2020

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Distinct molecular mechanisms of Fas resistance in murine B lymphoma cells.

31 March 2020

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

31 March 2020

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I-FLICE, a novel inhibitor of tumor necrosis factor receptor-1- and CD-95-induced apoptosis

31 March 2020

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Death effector domain-containing herpesvirus and poxvirus proteins inhibit both Fas- and TNFR1-induced apoptosis

31 March 2020

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Expression of K13/v-FLIP gene of human herpesvirus 8 and apoptosis in Kaposi's sarcoma spindle cells.

31 March 2020

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Immune escape of tumors in vivo by expression of cellular FLICE-inhibitory protein

31 March 2020

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The inhibitor of death receptor signaling, FLICE-inhibitory protein defines a new class of tumor progression factors

31 March 2020

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Inhibition of the death receptor pathway by cFLIP confers partial engraftment of MHC class I-deficient stem cells and reduces tumor clearance in perforin-deficient mice

31 March 2020

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Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule

31 March 2020

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The Survivin saga goes in vivo

31 March 2020

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A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

31 March 2020

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Anti-apoptosis gene, survivin, and prognosis of neuroblastoma

31 March 2020

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Transgenic expression of survivin in keratinocytes counteracts UVB-induced apoptosis and cooperates with loss of p53

31 March 2020

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Cancer gene therapy using a survivin mutant adenovirus

31 March 2020

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ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

31 March 2020

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Blockade of the granzyme B/perforin pathway through overexpression of the serine protease inhibitor PI-9/SPI-6 constitutes a mechanism for immune escape by tumors

31 March 2020

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Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype.

31 March 2020

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Bax suppresses tumorigenesis and stimulates apoptosis in vivo

31 March 2020

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Overexpression of the death-promoting gene bax-alpha which is downregulated in breast cancer restores sensitivity to different apoptotic stimuli and reduces tumor growth in SCID mice

31 March 2020

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Mutational inactivation of the proapoptotic gene BAX confers selective advantage during tumor clonal evolution

31 March 2020

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Inactivation of the apoptosis effector Apaf-1 in malignant melanoma

31 March 2020

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Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN

31 March 2020

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Lymphocyte apoptosis induced by CD95 (APO-1/Fas) ligand-expressing tumor cells--a mechanism of immune evasion?

31 March 2020

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Expression of APO-1 (CD95), a member of the NGF/TNF receptor superfamily, in normal and neoplastic colon epithelium

31 March 2020

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Loss of CD95 expression is linked to most but not all p53 mutants in European hepatocellular carcinoma

31 March 2020

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Oncogenic Ras inhibits Fas ligand-mediated apoptosis by downregulating the expression of Fas.

31 March 2020

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Fas gene mutation in the progression of adult T cell leukemia

31 March 2020

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The development of lymphomas in families with autoimmune lymphoproliferative syndrome with germline Fas mutations and defective lymphocyte apoptosis

31 March 2020

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Identification of XAF1 as an antagonist of XIAP anti-Caspase activity

31 March 2020

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p53 status and the efficacy of cancer therapy in vivo

31 March 2020

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p53 mutations increase resistance to ionizing radiation

31 March 2020

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Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

31 March 2020

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Disruption of p53 in human cancer cells alters the responses to therapeutic agents

31 March 2020

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INK4a/ARF mutations accelerate lymphomagenesis and promote chemoresistance by disabling p53.

31 March 2020

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ASPP proteins specifically stimulate the apoptotic function of p53

31 March 2020

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

31 March 2020

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Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase

31 March 2020

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PIK3CA is implicated as an oncogene in ovarian cancer.

31 March 2020

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Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

31 March 2020

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High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

31 March 2020

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Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

31 March 2020

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AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas

31 March 2020

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Cancer multidrug resistance

31 March 2020

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Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line

31 March 2020

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The drug efflux protein, P-glycoprotein, additionally protects drug-resistant tumor cells from multiple forms of caspase-dependent apoptosis

31 March 2020

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Nuclear factor-kappa B, cancer, and apoptosis

31 March 2020

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Aberrant rel/nfkb genes and activity in human cancer

31 March 2020

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Defective IkappaBalpha in Hodgkin cell lines with constitutively active NF-kappaB.

31 March 2020

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Extracellular matrix proteins protect small cell lung cancer cells against apoptosis: a mechanism for small cell lung cancer growth and drug resistance in vivo

31 March 2020

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Constitutive activation of Stat3 signaling confers resistance to apoptosis in human U266 myeloma cells

31 March 2020

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From bench to clinic with apoptosis-based therapeutic agents

31 March 2020

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Tumoricidal activity of tumor necrosis factor-related apoptosis-inducing ligand in vivo.

31 March 2020

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Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy

31 March 2020

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Recombinant tumor necrosis factor: its effect and its synergism with interferon-gamma on a variety of normal and transformed human cell lines

31 March 2020

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High-dose recombinant tumor necrosis factor alpha in combination with interferon gamma and melphalan in isolation perfusion of the limbs for melanoma and sarcoma

31 March 2020

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The kiss of death: promises and failures of death receptors and ligands in cancer therapy

31 March 2020

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Anti-cancer activity of targeted pro-apoptotic peptides

31 March 2020

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bcl-2 antisense therapy chemosensitizes human melanoma in SCID mice

31 March 2020

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Phase I clinical and pharmacokinetic study of bcl-2 antisense oligonucleotide therapy in patients with non-Hodgkin's lymphoma

31 March 2020

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Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides

31 March 2020

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RNA interference: listening to the sound of silence

31 March 2020

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Rescuing the function of mutant p53.

31 March 2020

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Inhibition of the growth of pre-established subcutaneous tumor nodules of human prostate cancer cells by single injection of the recombinant adenovirus p53 expression vector

31 March 2020

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Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-kappaB

31 March 2020

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BH3-Only proteins-essential initiators of apoptotic cell death

31 March 2020

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

31 March 2020

1 reference

31 March 2020

Identifiers

DOI

10.1038/NRC776

1 reference

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

25344

1025499462

0 references

25344

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference