(Q52536487)

2 May 2018

title

Inhibition of telomerase limits the growth of human cancer cells. (English)

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2 May 2018

1

Hahn WC

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2 May 2018

author name string

Stewart SA

2

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2 May 2018

Brooks MW

3

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2 May 2018

York SG

4

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2 May 2018

Eaton E

5

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2 May 2018

Kurachi A

6

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2 May 2018

Beijersbergen RL

7

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2 May 2018

Knoll JH

8

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2 May 2018

Meyerson M

9

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2 May 2018

Weinberg RA

10

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2 May 2018

language of work or name

English

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publication date

1 October 1999

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2 May 2018

published in

Nature Medicine

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2 May 2018

volume

5

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2 May 2018

page(s)

1164-1170

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2 May 2018

issue

10

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2 May 2018

https://scigraph.springernature.com/pub.10.1038/13495

exact match

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cites work

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Telomeres shorten during ageing of human fibroblasts

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Telomere shortening and tumor formation by mouse cells lacking telomerase RNA

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7 January 2021

Telomere length dynamics and chromosomal instability in cells derived from telomerase null mice

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Telomerase activity in human ovarian carcinoma

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Absence of cancer-associated changes in human fibroblasts immortalized with telomerase

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7 January 2021

The RNA component of human telomerase

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7 January 2021

Telomerase catalytic subunit homologs from fission yeast and human

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7 January 2021

hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization

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7 January 2021

Human telomerase contains evolutionarily conserved catalytic and structural subunits

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7 January 2021

Isolation of a candidate human telomerase catalytic subunit gene, which reveals complex splicing patterns in different cell types.

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7 January 2021

Telomerase activation by hTRT in human normal fibroblasts and hepatocellular carcinomas

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7 January 2021

Specific association of human telomerase activity with immortal cells and cancer

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7 January 2021

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Reconstitution of telomerase activity in normal human cells leads to elongation of telomeres and extended replicative life span

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7 January 2021

Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization

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7 January 2021

Telomerase activity is sufficient to allow transformed cells to escape from crisis

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7 January 2021

Telomerase extends the lifespan of virus-transformed human cells without net telomere lengthening

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Creation of human tumour cells with defined genetic elements

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A survey of telomerase activity in human cancer

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Reversing time: origin of telomerase

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Expression of SV40 large T antigen, but not small t antigen, is required for the induction of chromosomal aberrations in transformed human cells

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Telomere length dynamics in human lymphocyte subpopulations measured by flow cytometry.

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p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2

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Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

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7 January 2021

Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines

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7 January 2021

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A gentle fixation and permeabilization method for combined cell surface and intracellular staining with improved precision in DNA quantification

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Identifiers

DOI

10.1038/13495

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2 May 2018

PubMed ID

10502820

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2 May 2018