(Q40722888)

English

Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors

scientific article published on 21 June 2002

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scholarly article

1 reference

Europe PubMed Central

23 September 2017

Mitochondria are direct targets of the lipoxygenase inhibitor MK886. A strategy for cell killing by combined treatment with MK886 and cyclooxygenase inhibitors (English)

1 reference

Europe PubMed Central

23 September 2017

1 reference

ChEBI release 2020-05-28

10

1 reference

Europe PubMed Central

23 September 2017

Valeria Petronilli

object named as

Valeria Petronilli

5

0 references

object named as

Luca Scorrano

3

0 references

7

object named as

Maurizio Prato

2 references

Europe PubMed Central

23 September 2017

ORCID Public Data File 2021

6

object named as

Claudia Cusan

1 reference

Europe PubMed Central

23 September 2017

Francesco Pagano

9

object named as

Francesco Pagano

1 reference

Europe PubMed Central

23 September 2017

author name string

Arianna Gugliucci

1

1 reference

Europe PubMed Central

23 September 2017

Laura Ranzato

2

1 reference

Europe PubMed Central

23 September 2017

Raffaele Colonna

4

1 reference

Europe PubMed Central

23 September 2017

Mariangela Mancini

8

1 reference

Europe PubMed Central

23 September 2017

language of work or name

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publication date

21 June 2002

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Europe PubMed Central

23 September 2017

number of pages

7

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Journal of Biological Chemistry

1 reference

Europe PubMed Central

23 September 2017

277

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Europe PubMed Central

23 September 2017

31789-31795

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Europe PubMed Central

23 September 2017

35

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Europe PubMed Central

23 September 2017

A mitochondrial perspective on cell death

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

1 reference

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Bcl-2 inhibits the mitochondrial release of an apoptogenic protease

1 reference

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21 January 2018

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

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21 January 2018

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

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21 January 2018

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

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21 January 2018

On the involvement of a cyclosporin A sensitive mitochondrial pore in myocardial reperfusion injury

1 reference

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21 January 2018

Mitochondrial transport of cations: channels, exchangers, and permeability transition.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Arachidonic acid causes cell death through the mitochondrial permeability transition. Implications for tumor necrosis factor-alpha aopototic signaling

1 reference

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21 January 2018

Cyclooxygenase and lipoxygenase inhibitors in cancer therapy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

The role of cyclooxygenases in inflammation, cancer, and development

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Arachidonic acid as a bioactive molecule

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Deletion of cytosolic phospholipase A(2) suppresses Apc(Min)-induced tumorigenesis

1 reference

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21 January 2018

Movement of Bax from the cytosol to mitochondria during apoptosis

1 reference

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21 January 2018

Oligomeric C-terminal truncated Bax preferentially releases cytochrome c but not adenylate kinase from mitochondria, outer membrane vesicles and proteoliposomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Bax directly induces release of cytochrome c from isolated mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Role of BAX in the apoptotic response to anticancer agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Arachidonic acid stimulates prostate cancer cell growth: critical role of 5-lipoxygenase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

5-Lipoxygenase inhibitors reduce PC-3 cell proliferation and initiate nonnecrotic cell death.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Perturbations in the control of cellular arachidonic acid levels block cell growth and induce apoptosis in HL-60 cells.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Lipoxygenases and their involvement in programmed cell death

1 reference

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21 January 2018

On the effects of paraquat on isolated mitochondria. Evidence that paraquat causes opening of the cyclosporin A-sensitive permeability transition pore synergistically with nitric oxide.

1 reference

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21 January 2018

Mitochondria and cell death. Mechanistic aspects and methodological issues

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

5-Lipoxygenase-activating protein (FLAP)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

5-lipoxygenase-activating protein is an arachidonate binding protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Suppression of intestinal polyposis in Apc delta716 knockout mice by inhibition of cyclooxygenase 2 (COX-2)

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Up-regulation of cyclooxygenase 2 gene expression in human colorectal adenomas and adenocarcinomas

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Relationship between arachidonate--phospholipid remodeling and apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Intracellular unesterified arachidonic acid signals apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Phospholipase A2 is necessary for tumor necrosis factor alpha-induced ceramide generation in L929 cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M204450200

21 January 2018

Aspirin use and reduced risk of fatal colon cancer

1 reference

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21 January 2018

Many actions of cyclooxygenase-2 in cellular dynamics and in cancer

1 reference

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21 January 2018

Identifiers

10.1074/JBC.M204450200

1 reference

Europe PubMed Central

23 September 2017

1 reference

Europe PubMed Central

23 September 2017

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