(Q33641659)

28 July 2017

title

Targeted deletion of the zebrafish obscurin A RhoGEF domain affects heart, skeletal muscle and brain development (English)

1 reference

28 July 2017

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Maide O Raeker

1

1 reference

28 July 2017

Ashley N Bieniek

2

1 reference

28 July 2017

Alison S Ryan

3

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28 July 2017

Huai-Jen Tsai

4

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28 July 2017

Katelin M Zahn

5

1 reference

28 July 2017

Mark W Russell

6

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28 July 2017

language of work or name

English

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publication date

26 November 2009

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28 July 2017

published in

Developmental Biology

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28 July 2017

volume

337

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28 July 2017

issue

2

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28 July 2017

page(s)

432-443

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Obscurin determines the architecture of the longitudinal sarcoplasmic reticulum.

28 July 2017

cites work

1 reference

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TC10 controls human myofibril organization and is activated by the sarcomeric RhoGEF obscurin

21 June 2018

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The DH-PH region of the giant protein UNC-89 activates RHO-1 GTPase in Caenorhabditis elegans body wall muscle

21 June 2018

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The rho-guanine nucleotide exchange factor domain of obscurin regulates assembly of titin at the Z-disk through interactions with Ran binding protein 9

21 June 2018

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Genesis of neuronal and glial progenitors in the cerebellar cortex of peripuberal and adult rabbits

21 June 2018

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Interactions with titin and myomesin target obscurin and obscurin-like 1 to the M-band: implications for hereditary myopathies.

21 June 2018

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The genesis of retinal architecture: an emerging role for mechanical interactions?

21 June 2018

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New aspects of obscurin in human striated muscles

21 June 2018

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Rho GTPases and their regulators in neuronal functions and development

21 June 2018

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21 June 2018

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Obscurin-like 1, OBSL1, is a novel cytoskeletal protein related to obscurin

21 June 2018

1 reference

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Obscurin modulates the assembly and organization of sarcomeres and the sarcoplasmic reticulum

21 June 2018

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Loss of FilaminC (FLNc) results in severe defects in myogenesis and myotube structure

21 June 2018

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Obscurin: a multitasking muscle giant

21 June 2018

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Rho GTPases and the control of cell behaviour

21 June 2018

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21 June 2018

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Essential role of obscurin in cardiac myofibrillogenesis and hypertrophic response: evidence from small interfering RNA-mediated gene silencing.

21 June 2018

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Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice

21 June 2018

1 reference

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The role of the Rho GTPases in neuronal development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Dynamics of obscurin localization during differentiation and remodeling of cardiac myocytes: obscurin as an integrator of myofibrillar structure

21 June 2018

1 reference

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Rho-family GTPases: it's not only Rac and Rho (and I like it).

21 June 2018

1 reference

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Obscurin regulates the organization of myosin into A bands

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

C. elegans PAT-6/actopaxin plays a critical role in the assembly of integrin adhesion complexes in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Obscurin is a ligand for small ankyrin 1 in skeletal muscle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Signaling between focal adhesion kinase and trio

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Guanine nucleotide exchange factors for Rho GTPases: turning on the switch

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Muscular dystrophies involving the dystrophin-glycoprotein complex: an overview of current mouse models.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Identification, tissue expression and chromosomal localization of human Obscurin-MLCK, a member of the titin and Dbl families of myosin light chain kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

The Trio family of guanine-nucleotide-exchange factors: regulators of axon guidance.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Rho GTPases in neuronal morphogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Skeletal muscle deformity and neuronal disorder in Trio exchange factor-deficient mouse embryos

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Patterning of the zebrafish retina by a wave of sonic hedgehog activity.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

RhoA signaling via serum response factor plays an obligatory role in myogenic differentiation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

NMR structure and mutagenesis of the N-terminal Dbl homology domain of the nucleotide exchange factor Trio

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

UNC-73 activates the Rac GTPase and is required for cell and growth cone migrations in C. elegans.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Rho GTPases and signaling networks

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

The Caenorhabditis elegans gene unc-89, required fpr muscle M-line assembly, encodes a giant modular protein composed of Ig and signal transduction domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Proliferating subventricular zone cells in the adult mammalian forebrain can differentiate into neurons and glia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Restricted proliferation and migration of postnatally generated neurons derived from the forebrain subventricular zone

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

The Rho family GTPases RhoA, Rac1, and CDC42Hs regulate transcriptional activation by SRF

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

X chromosome-linked muscular dystrophy (mdx) in the mouse

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

The teleost retina as a model for developmental and regeneration biology

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Obscurin is required for the lateral alignment of striated myofibrils in zebrafish.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Identification of a zebrafish model of muscular dystrophy.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Dystrophin is required for the formation of stable muscle attachments in the zebrafish embryo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Intracardiac fluid forces are an essential epigenetic factor for embryonic cardiogenesis

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

C. elegans PAT-4/ILK functions as an adaptor protein within integrin adhesion complexes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Distinct roles for the two Rho GDP/GTP exchange factor domains of kalirin in regulation of neurite growth and neuronal morphology.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

Kalirin, a GDP/GTP exchange factor of the Dbl family, is localized to nerve, muscle, and endocrine tissue during embryonic rat development

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819229

The rho-guanine nucleotide exchange factor domain of obscurin activates rhoA signaling in skeletal muscle.

30 October 2018

1 reference

Crossref

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.11.018

10.1016/J.YDBIO.2009.11.018

7 January 2021

Identifiers

DOI

1 reference

28 July 2017

1 reference

28 July 2017

1 reference