(Q34268892)

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Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth

scientific article published on October 24, 2003

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Rapid response of cardiac obscurin gene cluster to aortic stenosis: differential activation of Rho-GEF and MLCK and involvement in hypertrophic growth (English)

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Europe PubMed Central

1 August 2017

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10.1016/J.BBRC.2003.09.035

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10.1016/J.BBRC.2003.09.035

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Aikaterini Kontrogianni-Konstantopoulos

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Aikaterini Kontrogianni-Konstantopoulos

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Robert J. Bloch

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Kun Yang

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Andrei B. Borisov

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Maide O. Raeker

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David M. Kurnit

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Mark W. Russell

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1 October 2003

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24 October 2003

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Biochemical and Biophysical Research Communications

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910-918

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The complete gene sequence of titin, expression of an unusual approximately 700-kDa titin isoform, and its interaction with obscurin identify a novel Z-line to I-band linking system

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Identification, tissue expression and chromosomal localization of human Obscurin-MLCK, a member of the titin and Dbl families of myosin light chain kinases

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10.1016/J.BBRC.2003.09.035

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Obscurin, a giant sarcomeric Rho guanine nucleotide exchange factor protein involved in sarcomere assembly

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10.1016/J.BBRC.2003.09.035

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Molecular mechanisms of myocardial remodeling

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Obscurin is a ligand for small ankyrin 1 in skeletal muscle

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10.1016/J.BBRC.2003.09.035

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Myosin light chain kinase mediates sarcomere organization during cardiac hypertrophy in vitro

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Various hypertrophic stimuli induce distinct phenotypes in cardiomyocytes

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Immunofluorescence and immunogold electron microscopy of desmin in isolated adult heart myocytes of the rat

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10.1016/J.BBRC.2003.09.035

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Molecular basis of cardiac hypertrophy

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The low molecular weight GTPase Rho regulates myofibril formation and organization in neonatal rat ventricular myocytes. Involvement of Rho kinase

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Dedicated myosin light chain kinases with diverse cellular functions

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Myosin light chain kinases

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Tuning the human heart molecular motors by myosin light chains

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The overall pattern of cardiac contraction depends on a spatial gradient of myosin regulatory light chain phosphorylation

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Fishing out proteins that bind to titin

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20 March 2024

Identifiers

10.1016/J.BBRC.2003.09.035

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Europe PubMed Central

1 August 2017

1 reference

Europe PubMed Central

1 August 2017

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