(Q33642446)

28 July 2017

title

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders (English)

1 reference

28 July 2017

0 references

Kartik Sunagar

5

0 references

Aaron Earl Darling

Aaron Darling

4

0 references

Agostinho Antunes

Agostinho Antunes

8

0 references

Glenn F King

Glenn F King

10

0 references

Sandy Pineda Gonzalez

1 reference

ORCID Public Data File 2021

Bryan Grieg Fry

9

Bryan G Fry

1 reference

28 July 2017

6

Eivind A B Undheim

1 reference

28 July 2017

Sandy S Pineda

1

1 reference

28 July 2017

Brianna L Sollod

2

1 reference

28 July 2017

David Wilson

3

1 reference

28 July 2017

Laurence Kely

7

1 reference

28 July 2017

language of work or name

English

0 references

publication date

5 March 2014

1 reference

28 July 2017

1 reference

28 July 2017

volume

15

1 reference

28 July 2017

page(s)

177

1 reference

Molecular evolution of vertebrate neurotrophins: co-option of the highly conserved nerve growth factor gene into the advanced snake venom arsenalf

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Three-fingered RAVERs: Rapid Accumulation of Variations in Exposed Residues of snake venom toxins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

SVM-based prediction of propeptide cleavage sites in spider toxins identifies toxin innovation in an Australian tarantula.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Do vicinal disulfide bridges mediate functionally important redox transformations in proteins?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

The insecticidal potential of venom peptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Molecular phylogeny and evolution of the proteins encoded by coleoid (cuttlefish, octopus, and squid) posterior venom glands

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

The venom optimization hypothesis revisited.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Differential evolution and neofunctionalization of snake venom metalloprotease domains

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Spider-venom peptides: structure, pharmacology, and potential for control of insect pests.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Detecting individual sites subject to episodic diversifying selection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Investigating the chemical profile of regenerated scorpion (Parabuthus transvaalicus) venom in relation to metabolic cost and toxicity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Conus venom peptide pharmacology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

MrBayes 3.2: Efficient Bayesian Phylogenetic Inference and Model Choice Across a Large Model Space

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Spider-venom peptides as therapeutics.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Venoms as a platform for human drugs: translating toxins into therapeutics

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

A random effects branch-site model for detecting episodic diversifying selection.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

B2G-FAR, a species-centered GO annotation repository

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Datamonkey 2010: a suite of phylogenetic analysis tools for evolutionary biology

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Mining on scorpion venom biodiversity

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Peptide toxins that selectively target insect Na(V) and Ca(V) channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

The Janus-faced atracotoxins are specific blockers of invertebrate K(Ca) channels.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

High-throughput functional annotation and data mining with the Blast2GO suite

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Proteases for processing proneuropeptides into peptide neurotransmitters and hormones

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

PAML 4: phylogenetic analysis by maximum likelihood

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Molecular diversification in spider venoms: a web of combinatorial peptide libraries

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Robust inference of positive selection from recombining coding sequences

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Neuropeptide-processing enzymes: applications for drug discovery

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

From genome to "venome": molecular origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences and related body proteins

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Not so different after all: a comparison of methods for detecting amino acid sites under selection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Bayes empirical bayes inference of amino acid sites under positive selection

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

A novel strategy for the identification of toxinlike structures in spider venom.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Were arachnids the first to use combinatorial peptide libraries?

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Improved prediction of signal peptides: SignalP 3.0

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Australian funnel-web spiders: master insecticide chemists.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Assembling an arsenal: origin and evolution of the snake venom proteome inferred from phylogenetic analysis of toxin sequences

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Scanning mutagenesis of a Janus-faced atracotoxin reveals a bipartite surface patch that is essential for neurotoxic function

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

The effect of recombination on the accuracy of phylogeny estimation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Discovery and structure of a potent and highly specific blocker of insect calcium channels

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Functional significance of the beta hairpin in the insecticidal neurotoxin omega-atracotoxin-Hv1a

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Mono- and dibasic proteolytic cleavage sites in insect neuroendocrine peptide precursors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Speciation of cone snails and interspecific hyperdivergence of their venom peptides. Potential evolutionary significance of introns

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Molecular genetics of ecological diversification: duplication and rapid evolution of toxin genes of the venomous gastropod Conus

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Likelihood ratio tests for detecting positive selection and application to primate lysozyme evolution

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

The structure of a novel insecticidal neurotoxin, omega-atracotoxin-HV1, from the venom of an Australian funnel web spider

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Evolution by the birth-and-death process in multigene families of the vertebrate immune system

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Characterization and cloning of insecticidal peptides from the primitive weaving spider Diguetia canities

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Sequence of the cDNA coding for the lethal neurotoxin Tx1 from the Brazilian "armed" spider Phoneutria nigriventer predicts the synthesis and processing of a preprotoxin

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

A common structural motif incorporating a cystine knot and a triple-stranded beta-sheet in toxic and inhibitory polypeptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Rapid amplification of complementary DNA ends for generation of full-length complementary DNAs: thermal RACE.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Combinatorial peptide libraries in drug design: lessons from venomous cone snails

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Sequence logos: a new way to display consensus sequences

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Constant and hypervariable regions in conotoxin propeptides

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Complex cocktails: the evolutionary novelty of venoms

28 July 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Molecular evolution and phylogeny of elapid snake venom three-finger toxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Tarantulas: eight-legged pharmacists and combinatorial chemists

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Scanning mutagenesis of omega-atracotoxin-Hv1a reveals a spatially restricted epitope that confers selective activity against insect calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Structure-function studies of omega-atracotoxin, a potent antagonist of insect voltage-gated calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

The omega-atracotoxins: selective blockers of insect M-LVA and HVA calcium channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

A model genetic system for testing the in vivo function of peptide toxins.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Spider venom toxin protects plants from insect attack.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

cDNA sequence and in vitro folding of GsMTx4, a specific peptide inhibitor of mechanosensitive channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

An overview of peptide toxins from the venom of the Chinese bird spider Selenocosmia huwena Wang [=Ornithoctonus huwena (Wang)].

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Molecular diversity and evolution of cystine knot toxins of the tarantula Chilobrachys jingzhao

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Orally active acaricidal peptide toxins from spider venom.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Mechanisms for evolving hypervariability: the case of conopeptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

FUBAR: a fast, unconstrained bayesian approximation for inferring selection

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Role of the structurally disordered N- and C-terminal residues in the Janus-faced atracotoxins

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Searching protein structure databases with DaliLite v.3

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

A rational nomenclature for naming peptide toxins from spiders and other venomous animals

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Datamonkey: rapid detection of selective pressure on individual sites of codon alignments

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Automated phylogenetic detection of recombination using a genetic algorithm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Position-specific codon conservation in hypervariable gene families

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

TreeSAAP: Selection on Amino Acid Properties using phylogenetic trees

21 January 2018

1 reference

https://api.crossref.org/works/10.1186%2F1471-2164-15-177

Dracula's children: molecular evolution of vampire bat venom.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Molding the business end of neurotoxins by diversifying evolution

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Direct visualization of disulfide bonds through diselenide proxies using 77Se NMR spectroscopy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Cost of venom regeneration in Parabuthus transvaalicus (Arachnida: Buthidae).

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

Accelerated evolution and molecular surface of venom phospholipase A2 enzymes

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

A codon-based model of nucleotide substitution for protein-coding DNA sequences

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4029134

A novel membrane anchor function for the N-terminal amphipathic sequence of the signal-transducing protein IIAGlucose of the Escherichia coli phosphotransferase system

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24593665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Venomous cone snails: molecular phylogeny and the generation of toxin diversity

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24593665

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/1471-2164-15-177

1 reference

Dimensions Publication ID

28 July 2017

1 reference

https://scigraph.springernature.com/pub.10.1186/1471-2164-15-177

9 September 2019

1 reference

28 July 2017

1 reference