(Q33643674)

28 July 2017

title

Caspase proteolysis of the integrin beta4 subunit disrupts hemidesmosome assembly, promotes apoptosis, and inhibits cell migration (English)

1 reference

28 July 2017

1 reference

Michael E Werner

1

1 reference

28 July 2017

Feng Chen

2

1 reference

28 July 2017

Jose V Moyano

3

1 reference

28 July 2017

Fruma Yehiely

4

1 reference

28 July 2017

Jonathan C R Jones

5

1 reference

28 July 2017

Vincent L Cryns

6

1 reference

28 July 2017

language of work or name

English

0 references

publication date

18 December 2006

1 reference

Journal of Biological Chemistry

28 July 2017

published in

1 reference

28 July 2017

volume

282

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28 July 2017

issue

8

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28 July 2017

page(s)

5560-5569

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Caspase-3-dependent activation of calcium-independent phospholipase A2 enhances cell migration in non-apoptotic ovarian cancer cells

28 July 2017

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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21 June 2018

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Keratinocytes from patients lacking collagen XVII display a migratory phenotype

21 June 2018

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Proteolysis of the mismatch repair protein MLH1 by caspase-3 promotes DNA damage-induced apoptosis

21 June 2018

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Caspase-8-dependent HER-2 cleavage in response to tumor necrosis factor alpha stimulation is counteracted by nuclear factor kappaB through c-FLIP-L expression

21 June 2018

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Autocrine laminin-5 ligates alpha6beta4 integrin and activates RAC and NFkappaB to mediate anchorage-independent survival of mammary tumors

21 June 2018

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Alpha 6 beta 4 integrin regulates keratinocyte chemotaxis through differential GTPase activation and antagonism of alpha 3 beta 1 integrin

21 June 2018

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Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures

21 June 2018

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21 June 2018

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Caspase proteolysis of desmin produces a dominant-negative inhibitor of intermediate filaments and promotes apoptosis

21 June 2018

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Dynamics of the alpha6beta4 integrin in keratinocytes

21 June 2018

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beta4 integrin-dependent formation of polarized three-dimensional architecture confers resistance to apoptosis in normal and malignant mammary epithelium

21 June 2018

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Caspase proteolysis of the cohesin component RAD21 promotes apoptosis

21 June 2018

1 reference

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Interactions of a hemidesmosome component and actinin family members

21 June 2018

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The fate of desmosomal proteins in apoptotic cells

21 June 2018

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Caspase cleavage of vimentin disrupts intermediate filaments and promotes apoptosis

21 June 2018

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Caspase-dependent cleavage of ErbB-2 by geldanamycin and staurosporin

21 June 2018

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Cleavage and shedding of E-cadherin after induction of apoptosis

21 June 2018

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Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bcl-2 action

21 June 2018

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21 June 2018

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Biology and function of hemidesmosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Interaction of BP180 (type XVII collagen) and alpha6 integrin is necessary for stabilization of hemidesmosome structure

21 June 2018

1 reference

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Structure and assembly of hemidesmosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Hemidesmosome formation is initiated by the beta4 integrin subunit, requires complex formation of beta4 and HD1/plectin, and involves a direct interaction between beta4 and the bullous pemphigoid antigen 180

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Cleavage of beta-catenin and plakoglobin and shedding of VE-cadherin during endothelial apoptosis: evidence for a role for caspases and metalloproteinases

21 June 2018

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Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

21 June 2018

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Specific proteolysis of the kinase protein kinase C-related kinase 2 by caspase-3 during apoptosis. Identification by a novel, small pool expression cloning strategy

21 June 2018

1 reference

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Caspase-3-generated fragment of gelsolin: effector of morphological change in apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Caspase cleavage of keratin 18 and reorganization of intermediate filaments during epithelial cell apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

A minimal region on the integrin beta4 subunit that is critical to its localization in hemidesmosomes regulates the distribution of HD1/plectin in COS-7 cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Small pool expression screening: identification of genes involved in cell cycle control, apoptosis, and early development

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

A homozygous mutation in the integrin alpha6 gene in junctional epidermolysis bullosa with pyloric atresia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Lamin proteolysis facilitates nuclear events during apoptosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Beta4 integrin is required for hemidesmosome formation, cell adhesion and cell survival

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Cleavage of actin by interleukin 1 beta-converting enzyme to reverse DNase I inhibition

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Epithelial detachment due to absence of hemidesmosomes in integrin beta 4 null mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

The beta 4 subunit cytoplasmic domain mediates the interaction of alpha 6 beta 4 integrin with the cytoskeleton of hemidesmosomes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

IFAP 300 is common to desmosomes and hemidesmosomes and is a possible linker of intermediate filaments to these junctions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Molecular genetic studies of a human epidermal autoantigen (the 180-kD bullous pemphigoid antigen/BP180): identification of functionally important sequences within the BP180 molecule and evidence for an interaction between BP180 and alpha 6 integrin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Studies of the lamin proteinase reveal multiple parallel biochemical pathways during apoptotic execution

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Integrin beta 4 mutations associated with junctional epidermolysis bullosa with pyloric atresia

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Cloning and sequence analysis of beta-4 cDNA: an integrin subunit that contains a unique 118 kd cytoplasmic domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Isolation and characterization of a spontaneously immortalized human breast epithelial cell line, MCF-10

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Cytoplasmic domain of the 180-kD bullous pemphigoid antigen, a hemidesmosomal component: molecular and cell biologic characterization

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2819670

Apoptosis generates stable fragments of human type I keratins

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

Epstein-Barr Virus EBNA-2 gene expression enhances lymphotoxin production by B lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

Cell cycle and adhesion defects in mice carrying a targeted deletion of the integrin beta4 cytoplasmic domain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

The small heat shock protein alpha B-crystallin negatively regulates cytochrome c- and caspase-8-dependent activation of caspase-3 by inhibiting its autoproteolytic maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

Degradation of DIAP1 by the N-end rule pathway is essential for regulating apoptosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

An evolutionary conserved pathway of nuclear factor-kappaB activation involving caspase-mediated cleavage and N-end rule pathway-mediated degradation of IkappaBalpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

Cleavage of epidermal growth factor receptor by caspase during apoptosis is independent of its internalization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M603669200

Specific cleavage of alpha-fodrin during Fas- and tumor necrosis factor-induced apoptosis is mediated by an interleukin-1beta-converting enzyme/Ced-3 protease distinct from the poly(ADP-ribose) polymerase protease

21 January 2018

1 reference

12 December 2020

The role of laminin-5 and its receptors in mammary epithelial cell branching morphogenesis

1 reference

12 December 2020

Hemidesmosome protein dynamics in live epithelial cells

1 reference

12 December 2020

Crucial role of the specificity-determining loop of the integrin beta4 subunit in the binding of cells to laminin-5 and outside-in signal transduction

1 reference

12 December 2020

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M603669200

1 reference

28 July 2017

1 reference

28 July 2017

1 reference