(Q33646358)

28 July 2017

1 reference

title

Drug focus: Pharmacogenetic studies related to cyclophosphamide-based therapy (English)

1 reference

28 July 2017

Navin Pinto

1

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28 July 2017

Susan M Ludeman

series ordinal

2

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28 July 2017

M Eileen Dolan

series ordinal

3

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28 July 2017

publication date

1 December 2009

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28 July 2017

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28 July 2017

volume

10

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28 July 2017

issue

12

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28 July 2017

page(s)

1897-1903

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Association of cyclophosphamide drug-metabolizing enzyme polymorphisms and chemotherapy-related ovarian failure in breast cancer survivors

28 July 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Glutathione S-transferase M1 and T1 polymorphisms may predict adverse effects after therapy in children with medulloblastoma

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Relations between polymorphisms in drug-metabolising enzymes and toxicity of chemotherapy with cyclophosphamide, thiotepa and carboplatin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Relationship of glutathione S-transferase genotypes with side-effects of pulsed cyclophosphamide therapy in patients with systemic lupus erythematosus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

The role of genetic variability in drug metabolism pathways in breast cancer prognosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Clinical pharmacokinetics of cyclophosphamide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Increased transcriptional activity of the CYP3A4*1B promoter variant

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Evaluation of aldehyde dehydrogenase 1 promoter polymorphisms identified in human populations.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Population genetic structure of variable drug response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Polymorphism in glutathione S-transferase P1 is associated with susceptibility to chemotherapy-induced leukemia.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Role of aldehyde dehydrogenases in endogenous and xenobiotic metabolism.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Activity of allelic variants of Pi class human glutathione S-transferase toward chlorambucil

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Polymorphisms of human aldehyde dehydrogenases. Consequences for drug metabolism and disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Molecular epidemiology: on the path to prevention?

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Human CYP2B6: expression, inducibility and catalytic activities

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

The chemistry of the metabolites of cyclophosphamide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Aldehyde dehydrogenase-mediated cellular relative insensitivity to the oxazaphosphorines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Mechanisms of resistance to the toxicity of cyclophosphamide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

An overview of cyclophosphamide development and clinical applications.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

The partitioning of phosphoramide mustard and its aziridinium ions among alkylation and P-N bond hydrolysis reactions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Molecular epidemiology of the human glutathione S-transferase genotypes GSTM1 and GSTT1 in cancer susceptibility

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Nucleotide excision repair genes as determinants of cellular sensitivity to cyclophosphamide analogs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Molecular epidemiology: insights into cancer susceptibility, risk assessment, and prevention

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Human glutathione S-transferase theta (GSTT1): cDNA cloning and the characterization of a genetic polymorphism

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Glutathione-associated enzymes in anticancer drug resistance.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Cyclophosphamide cystitis—Identification of acrolein as the causative agent

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

The interaction of glutathione with 4-hydroxycyclophosphamide and phosphoramide mustard, studied by 31P nuclear magnetic resonance spectroscopy.

21 June 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

ABCC2-mediated biliary transport of 4-glutathionylcyclophosphamide and its contribution to elimination of 4-hydroxycyclophosphamide in rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Cytochrome P450 pharmacogenetics as a predictor of toxicity and clinical response to pulse cyclophosphamide in lupus nephritis

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

RESPONSE: re: modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Activity of four allelic forms of glutathione S-transferase hGSTP1-1 for diol epoxides of polycyclic aromatic hydrocarbons.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Human glutathione S-transferase P1 polymorphisms: relationship to lung tissue enzyme activity and population frequency distribution

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Polymorphisms within glutathione S-transferase genes and initial response to glucocorticoids in childhood acute lymphoblastic leukaemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Analysis of the host pharmacogenetic background for prediction of outcome and toxicity in diffuse large B-cell lymphoma treated with R-CHOP21.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Promoter polymorphisms in glutathione-S-transferase genes affect transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Influence of glutathione S-transferase A1 polymorphism on the pharmacokinetics of busulfan

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Association between a glutathione S-transferase A1 promoter polymorphism and survival after breast cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Genetic polymorphisms in glutathione-S-transferase genes (GSTM1, GSTT1, GSTP1) and survival after chemotherapy for invasive breast carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Glutathione S-transferase P1 genotype and prognosis in Hodgkin's lymphoma

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Polymorphic variation in GSTP1 modulates outcome following therapy for multiple myeloma.

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Associations between drug metabolism genotype, chemotherapy pharmacokinetics, and overall survival in patients with breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Association between glutathione S-transferase genotypes and Hodgkin's lymphoma risk and prognosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Expression of mu class glutathione S-transferase correlates with event-free survival in childhood acute lymphoblastic leukemia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2820268

Role of human liver microsomal CYP3A4 and CYP2B6 in catalyzing N-dechloroethylation of cyclophosphamide and ifosfamide

30 October 2018

1 reference

https://api.crossref.org/works/10.2217%2FPGS.09.134

Polymorphisms within glutathione S-transferase genes (GSTM1, GSTT1, GSTP1) and risk of relapse in childhood B-cell precursor acute lymphoblastic leukemia: a case-control study

21 January 2018

1 reference

12 December 2020

Involvement of human glutathione S-transferase isoenzymes in the conjugation of cyclophosphamide metabolites with glutathione

1 reference

12 December 2020

Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase

1 reference

12 December 2020

Role of O6-alkylguanine-DNA alkyltransferase in protecting against cyclophosphamide-induced toxicity and mutagenicity

1 reference

12 December 2020

Association between survival after treatment for breast cancer and glutathione S-transferase P1 Ile105Val polymorphism

1 reference

12 December 2020

Expression of glutathione S-transferases and cytochrome P450 in normal and tumor breast tissue

1 reference

12 December 2020

Cytochrome P450 3A pharmacogenetics: the road that needs traveled

1 reference

12 December 2020

Common allelic variants of cytochrome P4503A4 and their prevalence in different populations

1 reference

12 December 2020

NADPH-dependent enzyme-catalyzed reduction of aldophosphamide, the pivotal metabolite of cyclophosphamide

1 reference

12 December 2020

Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

1 reference

12 December 2020

Identifiers

DOI

10.2217/PGS.09.134

1 reference

28 July 2017

1 reference

28 July 2017

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