(Q33650945)

28 July 2017

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title

Cytokine gene therapy: hopes and pitfalls (English)

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28 July 2017

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P Nanni

1

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Pier-Luigi Lollini

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author name string

G Forni

series ordinal

2

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28 July 2017

P L Lollini

series ordinal

3

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28 July 2017

publication date

1 March 1999

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28 July 2017

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28 July 2017

volume

10

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28 July 2017

issue

3

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28 July 2017

page(s)

261-266

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Gene transfer in tumor therapy

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

The immune response elicited by mammary adenocarcinoma cells transduced with interferon-gamma and cytosine deaminase genes cures lung metastases by parental cells

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7 January 2021

Oncogenic proteins as tumor antigens

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7 January 2021

Paracrine cytokine adjuvants in cancer immunotherapy

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7 January 2021

A nonimmunogenic sarcoma transduced with the cDNA for interferon gamma elicits CD8+ T cells against the wild-type tumor: correlation with antigen presentation capability

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7 January 2021

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity

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7 January 2021

Anti-metastatic vaccination of tumor-bearing mice with IL-2-gene-inserted tumor cells

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7 January 2021

Retroviral transduction of interferon-gamma cDNA into a nonimmunogenic murine fibrosarcoma: generation of T cells in draining lymph nodes capable of treating established parental metastatic tumor

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7 January 2021

Growth inhibition of subcutaneously transplanted human glioma by transfection-induced tumor necrosis factor-alpha and augmentation of the effect by gamma-interferon

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7 January 2021

Targeting of cytokine gene expression to malignant melanoma cells using tissue specific promoter sequences.

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7 January 2021

Intratumoral injection of an adenovirus expressing interleukin 2 induces regression and immunity in a murine breast cancer model

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7 January 2021

Induction of antitumor immunity and treatment of preestablished tumor by interleukin-6-gene-transfected melanoma cells combined with low-dose interleukin-2

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7 January 2021

Treatment of human hepatocellular carcinoma by fibroblast-mediated human interferon alpha gene therapy in combination with adoptive chemoimmunotherapy

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7 January 2021

Gene therapy of metastatic cancer by in vivo retroviral gene targeting

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7 January 2021

Introduction of murine Il-4 gene into B16(F10) melanoma tumors by direct gene transfer with DNA-liposome complexes

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7 January 2021

In vivo cytokine gene transfer by gene gun reduces tumor growth in mice

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7 January 2021

Effect of irradiation on cytokine production, MHC antigen expression, and vaccine potential of interleukin-2 and interferon-gamma gene-modified melanoma cells

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7 January 2021

Direct Intratumoral Injection of an Adenovirus Expressing Interleukin-12 Induces Regression and Long-Lasting Immunity That Is Associated with Highly Localized Expression of Interleukin-12

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7 January 2021

Active immunotherapy with transiently transfected cytokine-secreting tumor cells inhibits breast cancer metastases in tumor-bearing animals

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7 January 2021

Gene gun-mediated skin transfection with interleukin 12 gene results in regression of established primary and metastatic murine tumors

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7 January 2021

Subcutaneous vaccination with irradiated, cytokine-producing tumor cells stimulates CD8+ cell-mediated immunity against tumors located in the "immunologically privileged" central nervous system

1 reference

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7 January 2021

Treatment of leukemia with fibroblast-mediated interferon-alpha gene therapy alone or in combination with doxorubicin

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7 January 2021

Genetic immunotherapy by intrapleural, intraperitoneal and subcutaneous injection of IL-2 gene-modified Lewis lung carcinoma cells

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7 January 2021

The effectiveness of active specific immunotherapy using interferon-gamma-gene-transduced tumor cells in a murine tumor model

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7 January 2021

A Phase I clinical trial of immunotherapy with interferon-gamma gene-modified autologous melanoma cells: monitoring the humoral immune response

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7 January 2021

Active immunization of metastatic melanoma patients with interleukin-2-transduced allogeneic melanoma cells: evaluation of efficacy and tolerability

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7 January 2021

Gene therapy for cancer: what have we done and where are we going?

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7 January 2021

Regression of bladder tumors in mice treated with interleukin 2 gene-modified tumor cells

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7 January 2021

Immunization with interleukin-2-secreting allogeneic mouse fibroblasts expressing melanoma-associated antigens prolongs the survival of mice with melanoma.

1 reference

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7 January 2021

Combination effect of vaccination with IL2 and IL4 cDNA transfected cells on the induction of a therapeutic immune response against Lewis lung carcinoma cells

1 reference

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7 January 2021

In vivo antitumor effect of cytotoxic T lymphocytes engineered to produce interferon-gamma by adenovirus-mediated genetic transduction

1 reference

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7 January 2021

Active immunotherapy of pancreatic cancer with tumor cells genetically engineered to secrete multiple cytokines

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

The effect of combined expression of interleukin 2 and interleukin 4 on the tumorigenicity and treatment of B16F10 melanoma

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

Antigen-specific regression of established tumors induced by active immunization with irradiated IL-12- but not B7-1-transfected tumor cells

1 reference

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7 January 2021

Combination therapy with suicide and cytokine genes for hepatic metastases of lung cancer

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

Local and systemic antitumor response after combined therapy of mouse metastatic tumors with tumor cells expressing IFN-alpha and HSVtk: perspectives for the generation of cancer vaccines

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

Multicomponent gene therapy vaccines for lung cancer: effective eradication of established murine tumors in vivo with interleukin-7/herpes simplex thymidine kinase-transduced autologous tumor and ex vivo activated dendritic cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

Inhibition of lung colonisation of a mouse mammary carcinoma by therapeutic vaccination with interferon-alpha gene-transduced tumor cells

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

Systemic effects of cytokines released by gene-transduced tumor cells: marked hyperplasia induced in small bowel by gamma-interferon transfectants through host lymphocytes

1 reference

https://api.crossref.org/works/10.1023%2FA%3A1008304721889

7 January 2021

Identifiers

DOI

10.1023/A:1008304721889

1 reference

28 July 2017

1 reference