(Q33653635)

28 July 2017

title

The macrophage LBP gene is an LXR target that promotes macrophage survival and atherosclerosis (English)

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28 July 2017

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1

Tamer Sallam

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28 July 2017

14

Peter Tontonoz

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28 July 2017

Ayaka Ito

2

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28 July 2017

Xin Rong

3

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28 July 2017

Jason Kim

4

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28 July 2017

Caroline van Stijn

5

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28 July 2017

Brian T Chamberlain

6

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28 July 2017

Michael E Jung

7

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28 July 2017

Lily C Chao

8

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28 July 2017

Marius Jones

9

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28 July 2017

Thomas Gilliland

10

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28 July 2017

XiaoHui Wu

11

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28 July 2017

Grace L Su

12

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28 July 2017

Rajendra K Tangirala

13

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28 July 2017

Cynthia Hong

15

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28 July 2017

publication date

26 March 2014

1 reference

Journal of Lipid Research

28 July 2017

published in

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28 July 2017

volume

55

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28 July 2017

issue

6

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28 July 2017

page(s)

1120-1130

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2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines

28 July 2017

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21 June 2018

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21 June 2018

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Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR.

21 June 2018

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LXR regulates cholesterol uptake through Idol-dependent ubiquitination of the LDL receptor

21 June 2018

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LXR ligand lowers LDL cholesterol in primates, is lipid neutral in hamster, and reduces atherosclerosis in mouse

21 June 2018

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Antiatherosclerotic effects of a novel synthetic tissue-selective steroidal liver X receptor agonist in low-density lipoprotein receptor-deficient mice

21 June 2018

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LXR signaling couples sterol metabolism to proliferation in the acquired immune response.

21 June 2018

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Ligand activation of LXR beta reverses atherosclerosis and cellular cholesterol overload in mice lacking LXR alpha and apoE

21 June 2018

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21 June 2018

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Attenuation of neuroinflammation and Alzheimer's disease pathology by liver x receptors

21 June 2018

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21 June 2018

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The arginase II gene is an anti-inflammatory target of liver X receptor in macrophages

21 June 2018

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Liver X receptors as integrators of metabolic and inflammatory signaling

21 June 2018

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Consequences and therapeutic implications of macrophage apoptosis in atherosclerosis: the importance of lesion stage and phagocytic efficiency

21 June 2018

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A role for the apoptosis inhibitory factor AIM/Spalpha/Api6 in atherosclerosis development

21 June 2018

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Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice.

21 June 2018

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21 June 2018

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Activation of liver X receptors and retinoid X receptors prevents bacterial-induced macrophage apoptosis

21 June 2018

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Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice

21 June 2018

1 reference

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LXR-dependent gene expression is important for macrophage survival and the innate immune response

21 June 2018

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Meet the relatives: a family of BPI- and LBP-related proteins

21 June 2018

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Lipopolysaccharide (LPS)-binding protein inhibits responses to cell-bound LPS

21 June 2018

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The phospholipid transfer protein gene is a liver X receptor target expressed by macrophages in atherosclerotic lesions

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Cholesteryl ester transfer protein: a novel target for raising HDL and inhibiting atherosclerosis

21 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Regulation and mechanisms of macrophage cholesterol efflux

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Identification of macrophage liver X receptors as inhibitors of atherosclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Synthetic LXR ligand inhibits the development of atherosclerosis in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Leukocyte ABCA1 controls susceptibility to atherosclerosis and macrophage recruitment into tissues.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Regulation of ATP-binding cassette sterol transporters ABCG5 and ABCG8 by the liver X receptors alpha and beta.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

High concentrations of lipopolysaccharide-binding protein in serum of patients with severe sepsis or septic shock inhibit the lipopolysaccharide response in human monocytes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

The orphan nuclear receptor LRH-1 potentiates the sterol-mediated induction of the human CETP gene by liver X receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

LPS-binding protein circulates in association with apoB-containing lipoproteins and enhances endotoxin-LDL/VLDL interaction

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Control of cellular cholesterol efflux by the nuclear oxysterol receptor LXR alpha

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

A cholesteryl ester transfer protein inhibitor attenuates atherosclerosis in rabbits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Lipopolysaccharide-binding protein and phospholipid transfer protein release lipopolysaccharides from gram-negative bacterial membranes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Mice lacking serum paraoxonase are susceptible to organophosphate toxicity and atherosclerosis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

LPS-binding protein protects mice from septic shock caused by LPS or gram-negative bacteria

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Targeted deletion of the lipopolysaccharide (LPS)-binding protein gene leads to profound suppression of LPS responses ex vivo, whereas in vivo responses remain intact

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Lipopolysaccharide-binding protein is required to combat a murine gram-negative bacterial infection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Control of transcriptional activation of the lipopolysaccharide binding protein (LBP) gene by proinflammatory cytokines.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Lipopolysaccharide (LPS)-binding protein is carried on lipoproteins and acts as a cofactor in the neutralization of LPS

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Lipopolysaccharide (LPS)-binding protein accelerates the binding of LPS to CD14.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Structure and function of lipopolysaccharide binding protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Trends in cardiovascular health metrics and associations with all-cause and CVD mortality among US adults

21 June 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Effect of macrophage overexpression of murine liver X receptor-alpha (LXR-alpha) on atherosclerosis in LDL-receptor deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Macrophage apoptosis exerts divergent effects on atherogenesis as a function of lesion stage.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Lipopolysaccharide-binding protein (LBP) is associated with total and cardiovascular mortality in individuals with or without stable coronary artery disease--results from the Ludwigshafen Risk and Cardiovascular Health Study (LURIC).

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Lipopolysaccharide-binding protein is increased in patients with psoriasis with metabolic syndrome, and correlates with C-reactive protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Phospholipid transfer protein is regulated by liver X receptors in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

The effects of cholesterol ester transfer protein inhibition on cholesterol efflux

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

The role of plasma lipid transfer proteins in lipoprotein metabolism and atherogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Macrophage phospholipid transfer protein contributes significantly to total plasma phospholipid transfer activity and its deficiency leads to diminished atherosclerotic lesion development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

No effect of C-reactive protein on early atherosclerosis development in apolipoprotein E*3-leiden/human C-reactive protein transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M047548

Macrophage liver X receptor is required for antiatherogenic activity of LXR agonists

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4031943

Lipopolysaccharide (LPS)-binding protein mediates LPS detoxification by chylomicrons

30 October 2018

1 reference

12 December 2020

No effect of C-reactive protein on early atherosclerosis in LDLR-/- / human C-reactive protein transgenic mice

1 reference

12 December 2020

An essential role for lipopolysaccharide-binding protein in pulmonary innate immune responses

1 reference

12 December 2020

Induction of hepatocyte lipopolysaccharide binding protein in models of sepsis and the acute-phase response

1 reference

12 December 2020

Identifiers

DOI

10.1194/JLR.M047548

1 reference

28 July 2017

1 reference

28 July 2017

1 reference