(Q33655872)

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Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA.

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12 February 2020

Chronic hypoxia augments depolarization-induced Ca2+ sensitization in pulmonary vascular smooth muscle through superoxide-dependent stimulation of RhoA (English)

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12 February 2020

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12 February 2020

Brad R S Broughton

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Brad R S Broughton

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12 February 2020

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Thomas C Resta

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12 February 2020

Benjimen R Walker

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Benjimen R Walker

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12 February 2020

author name string

Charles E Norton

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12 February 2020

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6 November 2009

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12 February 2020

American Journal of Physiology - Lung Cellular and Molecular Physiology

1 reference

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12 February 2020

298

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12 February 2020

2

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12 February 2020

L232-42

1 reference

Europe PubMed Central

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12 February 2020

Reactive oxygen species from NADPH oxidase contribute to altered pulmonary vascular responses in piglets with chronic hypoxia-induced pulmonary hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Actin cytoskeletal dynamics in smooth muscle: a new paradigm for the regulation of smooth muscle contraction.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Chronic hypoxia induces Rho kinase-dependent myogenic tone in small pulmonary arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Rho kinase (ROCK) inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Current topics in the regulatory mechanism underlying the Ca2+ sensitization of the contractile apparatus in vascular smooth muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Measurement of reactive oxygen species in cardiovascular studies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Disruption of smooth muscle gap junctions attenuates myogenic vasoconstriction of mesenteric resistance arteries

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Rho/Rho kinase signaling mediates increased basal pulmonary vascular tone in chronically hypoxic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Ca2+ channel-sarcoplasmic reticulum coupling: a mechanism of arterial myocyte contraction without Ca2+ influx

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

K+ depolarization induces RhoA kinase translocation to caveolae and Ca2+ sensitization of arterial muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Membrane depolarization-induced contraction of rat caudal arterial smooth muscle involves Rho-associated kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Specificity and mechanism of action of some commonly used protein kinase inhibitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Selective inhibition of protein kinase C isozymes by the indolocarbazole Gö 6976.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

28 July 2018

Vasoconstrictor effect of endothelin-1 on hypertensive pulmonary arterial smooth muscle involves Rho-kinase and protein kinase C

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Rho kinase inhibitors prevent endothelium-dependent contractions in the rat aorta

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

The superoxide dismutase mimetic, tempol, blunts right ventricular hypertrophy in chronic hypoxic rats.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Attenuation of acute hypoxic pulmonary vasoconstriction and hypoxic pulmonary hypertension in mice by inhibition of Rho-kinase.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Endothelin-1 and serotonin are involved in activation of RhoA/Rho kinase signaling in the chronically hypoxic hypertensive rat pulmonary circulation

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Generation of oxidative stress contributes to the development of pulmonary hypertension induced by hypoxia

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Inhibition of Rho-kinase attenuates hypoxia-induced angiogenesis in the pulmonary circulation.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Impaired NO-dependent inhibition of store- and receptor-operated calcium entry in pulmonary vascular smooth muscle after chronic hypoxia

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Contribution of oxygen radicals to altered NO-dependent pulmonary vasodilation in acute and chronic hypoxia

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Chronic hypoxia augments protein kinase G-mediated Ca2+ desensitization in pulmonary vascular smooth muscle through inhibition of RhoA/Rho kinase signaling

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Reactive oxygen species mediate RhoA/Rho kinase-induced Ca2+ sensitization in pulmonary vascular smooth muscle following chronic hypoxia

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Oxygen activates the Rho/Rho-kinase pathway and induces RhoB and ROCK-1 expression in human and rabbit ductus arteriosus by increasing mitochondria-derived reactive oxygen species: a newly recognized mechanism for sustaining ductal constriction

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Superoxide constricts rat pulmonary arteries via Rho-kinase-mediated Ca(2+) sensitization.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Hypoxic pulmonary hypertension: role of superoxide and NADPH oxidase (gp91phox).

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Pyrimidine nucleotides suppress KDRcurrents and depolarize rat cerebral arteries by activating Rho kinase

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Acute vasodilator effects of Rho-kinase inhibitors in neonatal rats with pulmonary hypertension unresponsive to nitric oxide

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Alterations in a redox oxygen sensing mechanism in chronic hypoxia

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Ca2+-dependent activation of Rho and Rho kinase in membrane depolarization-induced and receptor stimulation-induced vascular smooth muscle contraction

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: modulated by G proteins, kinases, and myosin phosphatase

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Depolarization induces Rho-Rho kinase-mediated myosin light chain phosphorylation in kidney tubular cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Ca2+ signaling in hypoxic pulmonary vasoconstriction: effects of myosin light chain and Rho kinase antagonists.

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Mechanisms of endothelin-1-induced contraction in pulmonary arteries from chronically hypoxic rats

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Agonist- and depolarization-induced signals for myosin light chain phosphorylation and force generation of cultured vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Hypoxia divergently regulates production of reactive oxygen species in human pulmonary and coronary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Superoxide reacts with hydroethidine but forms a fluorescent product that is distinctly different from ethidium: potential implications in intracellular fluorescence detection of superoxide

1 reference

https://api.crossref.org/works/10.1152%2FAJPLUNG.00276.2009

21 January 2018

Pressure-induced smooth muscle cell depolarization in pulmonary arteries from control and chronically hypoxic rats does not cause myogenic vasoconstriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

30 October 2018

Maintained upregulation of pulmonary eNOS gene and protein expression during recovery from chronic hypoxia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

30 October 2018

Lungs from chronically hypoxic rats have decreased pressor response to acute hypoxia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822557

30 October 2018

A simple assay of the superoxide generation rate with Tiron as an EPR-visible radical scavenger

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Arachidonic acid causes cyclooxygenase-dependent and -independent pulmonary vasodilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic hypoxia selectively augments endothelium-dependent pulmonary arterial vasodilation

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Endothelial NADPH oxidase as the source of oxidants in lungs exposed to ischemia or high K+

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The small G-protein Rac mediates depolarization-induced superoxide formation in human endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nitric oxide-dependent pulmonary vasodilation in polycythemic rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

L-type Ca(2+) channels, resting [Ca(2+)](i), and ET-1-induced responses in chronically hypoxic pulmonary myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic hypoxia decreases K(V) channel expression and function in pulmonary artery myocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization of the macula densa induces superoxide production via NAD(P)H oxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19897743

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPLUNG.00276.2009

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19897743%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19897743%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19897743%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

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