(Q33664353)

28 July 2017

1 reference

title

Effect of Non-Steroidal Anti-Inflammatory Drugs on Bone Healing (English)

1 reference

28 July 2017

1

Jessica Cottrell

1 reference

28 July 2017

J Patrick O'Connor

2

1 reference

28 July 2017

publication date

25 May 2010

1 reference

28 July 2017

1 reference

28 July 2017

volume

3

1 reference

28 July 2017

issue

5

1 reference

28 July 2017

page(s)

1668-1693

1 reference

Creative Commons Attribution 4.0 International

28 July 2017

copyright license

start time

25 May 2010

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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21 June 2018

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COX-2 and prostaglandin EP3/EP4 signaling regulate the tumor stromal proangiogenic microenvironment via CXCL12-CXCR4 chemokine systems

21 June 2018

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Prostaglandins in bone: bad cop, good cop?

21 June 2018

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A comparison of the effects of ibuprofen and rofecoxib on rabbit fibula osteotomy healing

21 June 2018

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Rescue of impaired fracture healing in COX-2-/- mice via activation of prostaglandin E2 receptor subtype 4.

21 June 2018

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Parecoxib and indomethacin delay early fracture healing: a study in rats

21 June 2018

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Celecoxib, NSAIDs and the skeleton

21 June 2018

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Posterolateral lumbar spine fusion with INFUSE bone graft

21 June 2018

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The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein

21 June 2018

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Nonsteroidal anti-inflammatory drug-induced fracture nonunion: an inhibition of angiogenesis?

21 June 2018

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Risk of Upper Gastrointestinal Injury and Events in Patients Treated With Cyclooxygenase (COX)-1/COX-2 Nonsteroidal Antiinflammatory Drugs (NSAIDs), COX-2 Selective NSAIDs, and Gastroprotective Cotherapy: An Appraisal of the Literature

21 June 2018

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Selective cyclooxygenase inhibition: its role in pain and anaesthesia

21 June 2018

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Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing

21 June 2018

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A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug use

21 June 2018

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Coxibs and cardiovascular disease

21 June 2018

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Cyclooxygenase isozymes: the biology of prostaglandin synthesis and inhibition.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Differential inhibition of fracture healing by non-selective and cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Cyclooxygenase-2 inhibitor inhibits the fracture healing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Bone morphogenetic protein 2 induces cyclo-oxygenase 2 in osteoblasts via a Cbfal binding site: role in effects of bone morphogenetic protein 2 in vitro and in vivo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Cyclooxygenase-2 regulates mesenchymal cell differentiation into the osteoblast lineage and is critically involved in bone repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The coxibs, selective inhibitors of cyclooxygenase-2.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effects of ketoralac tromethamine and indomethacin on primary and secondary bone healing. An experimental study in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effects of ketorolac on bone repair: A radiographic study in modeled demineralized bone matrix grafted rabbits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

5-Lipoxygenase metabolites inhibit bone formation in vitro

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The effect of postoperative nonsteroidal anti-inflammatory drug administration on spinal fusion

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The expression of cytokine activity by fracture callus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Current concepts in bone healing. Review of the literature

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

NSAID nephrotoxicity revisited: acute renal failure due to parenteral ketorolac

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Nitric oxide activates cyclooxygenase enzymes.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Indomethacin and aspirin: effect of nonsteroidal anti-inflammatory agents on the rate of fracture repair in the rat.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Non-steroidal anti-inflammatory agents in the management of Colles' fractures

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The effect of indomethacin, aspirin, and ibuprofen on bone ingrowth into a porous-coated implant.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Identification of a phorbol ester-repressible v-src-inducible gene

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Comparison between the effects of dexamethasone and indomethacin on bone wound healing.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Prophylaxis with indomethacin for heterotopic bone. After open reduction of fractures of the acetabulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

A serum- and glucocorticoid-regulated 4-kilobase mRNA encodes a cyclooxygenase-related protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Fracture healing in rats inhibited by locally administered indomethacin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Indomethacin-induced delayed fracture healing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Indomethacin-Induced Inhibition of Haversian Remodelling in Rabbits

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Inhibition of fracture healing by indomethacin in rats

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The effect on bone repair of aspirin cones placed in extraction sockets in dogs: a histopathologic study

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Pharmacological inhibition of 5-lipoxygenase accelerates and enhances fracture-healing

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Negative effects of parecoxib and indomethacin on tendon healing: an experimental study in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Analgesic effects of p38 kinase inhibitor treatment on bone fracture healing.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The effects of the short-term administration of low therapeutic doses of anti-COX-2 agents on the healing of fractures. An experimental study in rabbits

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effect of COX-2 inhibitors and non-steroidal anti-inflammatory drugs on a mouse fracture model

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Cyclooxygenase-2 inhibitor delays fracture healing in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Temporal effects of a COX-2-selective NSAID on bone ingrowth

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Parecoxib impairs early tendon repair but improves later remodeling

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effect of COX-2-specific inhibition on fracture-healing in the rat femur

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Heterotopic ossification prophylaxis with indomethacin increases the risk of long-bone nonunion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Influence of diclofenac (group of nonsteroidal anti-inflammatory drugs) on fracture healing

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Time-dependent inhibitory effects of indomethacin on spinal fusion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effect of tenoxicam on fracture healing in rat tibiae

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

COX-2 selective NSAID decreases bone ingrowth in vivo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The effect of cyclooxygenase-2 inhibitors on spinal fusion.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effect of diclofenac sodium on union of tibial fractures in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Cyclo-oxygenase 2 function is essential for bone fracture healing

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Nonunion of the femoral diaphysis. The influence of reaming and non-steroidal anti-inflammatory drugs.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The early stages of the repair of adult human diaphyseal fractures

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Indomethacin versus radiation therapy for prophylaxis against heterotopic ossification in acetabular fractures: a randomised, prospective study.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Preoperative ketorolac increases bleeding after tonsillectomy in children.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Aspirin and NSAID use in older women: effect on bone mineral density and fracture risk. Study of Osteoporotic Fractures Research Group

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

A controlled study comparing the effects of nabumetone, ibuprofen, and ibuprofen plus misoprostol on the upper gastrointestinal tract mucosa.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Inhibitory effect on bone formation and calcification exerted by the anti-inflammatory drug ibuprofen. An experimental study on adult rat with fracture

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Effects of short-term treatment with corticosteroids and indomethacin on bone healing. A mechanical study of osteotomies in rats

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

Bone repair inhibited by indomethacin: Effects on bone metabolism and strength of rabbit osteotomies

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4034003

The non-steroidal anti-inflammatory drug diclofenac reduces appearance of osteoblasts in bone defect healing in rats

30 October 2018

1 reference

12 December 2020

The effects of nonsteroidal anti-inflammatory drugs on posterior spinal fusions in the rat

1 reference

12 December 2020

Inducible cyclo-oxygenase (COX-2) mediates the induction of bone formation by mechanical loading in vivo

1 reference

12 December 2020

Leukotriene B4 stimulates osteoclastic bone resorption both in vitro and in vivo

1 reference

12 December 2020

The influence of ibuprofen on fracture repair: biomechanical, biochemical, histologic, and histomorphometric parameters in rats

1 reference

12 December 2020

Effect of nonsteroidal antiinflammatory drugs on fracture healing: a laboratory study in rats

1 reference

12 December 2020

The effect of indomethacin on tooth extraction wound healing in rats

1 reference

12 December 2020

Effect of indomethacin on fracture healing in rats

1 reference

12 December 2020

Effect of ibuprofen and indomethacin on bone metabolism reflected in bone strength

1 reference

12 December 2020

Effects of leukotrienes on osteoblastic cell proliferation

1 reference

12 December 2020

Inhibition of cyclooxygenase-2 rapidly reverses inflammatory hyperalgesia and prostaglandin E2 production

1 reference

12 December 2020

Effect of ibuprofen on mass and composition of fracture callus and bone. An experimental study on adult rat

1 reference

12 December 2020

Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats

1 reference

12 December 2020

No effects of piroxicam on osteopenia and recovery after Colles' fracture. A randomized, double-blind, placebo-controlled, prospective trial

1 reference

12 December 2020

Uncertain effect of indomethacin on physeal growth injury Experiments in rabbits

1 reference

12 December 2020

Prevention of fracture healing in rats by an inhibitor of angiogenesis

1 reference

12 December 2020

Inflammatory cells in normal human fracture healing

1 reference

12 December 2020

The effects of two nonsteroidal antiinflammatory drugs on limb swelling, joint stiffness, and bone torsional strength following fracture in a rabbit model

1 reference

12 December 2020

Risks of bleeding peptic ulcer associated with individual non-steroidal anti-inflammatory drugs

1 reference

12 December 2020

Release of prostaglandins from bone and muscle after tibial fracture. An experimental study in rabbits

1 reference

12 December 2020

Indomethacin compared with localized irradiation for the prevention of heterotopic ossification following surgical treatment of acetabular fractures

1 reference

12 December 2020

Effects of indomethacin on bone ingrowth

1 reference

12 December 2020

Recombinant human bone morphogenetic protein-2 overcomes the inhibitory effect of ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), on posterolateral lumbar intertransverse process spine fusion

1 reference

12 December 2020

Effects of a cyclooxygenase-2 inhibitor (rofecoxib) on bone healing

1 reference

12 December 2020

Indomethacin and bone trauma. Effects on remodeling of rabbit bone

1 reference

12 December 2020

Nonsteroidal antiinflammatory drugs and nonunion of humeral shaft fractures

1 reference

12 December 2020

Use of nonsteroidal anti-inflammatory drugs and risk of fractures

1 reference

12 December 2020

Effect of indomethacin on collagen metabolism of rat fracture callus in vitro

1 reference

12 December 2020

Effects of diclofenac on periosteal callus maturation in osteotomy healing in an animal model

1 reference

12 December 2020

Naproxen for 8 days can prevent heterotopic ossification after hip arthroplasty

1 reference

12 December 2020

Effects of phenylbutazone and indomethacin on the post-operative course following experimental orthopaedic surgery in dogs

1 reference

12 December 2020

The Effect of Indomethacin Upon Experimental Fractures in the Rat

1 reference

12 December 2020

Mice lacking 5-lipoxygenase have increased cortical bone thickness

1 reference

12 December 2020

The cell and molecular biology of fracture healing

1 reference

12 December 2020

Identifiers

DOI

10.3390/PH3051668

1 reference

28 July 2017

1 reference

28 July 2017

1 reference