(Q33667663)

28 July 2017

title

Inhibition of the K+ channel KCa3.1 ameliorates T cell-mediated colitis (English)

1 reference

28 July 2017

1 reference

Lie Di

1

1 reference

28 July 2017

Shekhar Srivastava

2

1 reference

28 July 2017

Olga Zhdanova

3

1 reference

28 July 2017

Yi Ding

4

1 reference

28 July 2017

Zhai Li

5

1 reference

28 July 2017

Heike Wulff

6

1 reference

28 July 2017

Maria Lafaille

7

1 reference

28 July 2017

Edward Y Skolnik

8

1 reference

28 July 2017

language of work or name

English

0 references

publication date

8 January 2010

1 reference

Proceedings of the National Academy of Sciences of the United States of America

28 July 2017

published in

1 reference

28 July 2017

volume

107

1 reference

28 July 2017

issue

4

1 reference

28 July 2017

page(s)

1541-1546

1 reference

A protective function for interleukin 17A in T cell-mediated intestinal inflammation

28 July 2017

cites work

1 reference

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14 July 2018

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Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block

14 July 2018

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Protein histidine phosphatase 1 negatively regulates CD4 T cells by inhibiting the K+ channel KCa3.1

14 July 2018

1 reference

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The intermediate-conductance calcium-activated potassium channel KCa3.1 contributes to atherogenesis in mice and humans

14 July 2018

1 reference

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Induction and effector functions of T(H)17 cells.

14 July 2018

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Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis

14 July 2018

1 reference

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Calcium signalling in lymphocyte activation and disease

14 July 2018

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IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways

14 July 2018

1 reference

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New insights into the molecular mechanisms of store-operated Ca2+ signaling in T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

14 July 2018

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

14 July 2018

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Phosphatidylinositol-3 phosphatase myotubularin-related protein 6 negatively regulates CD4 T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Potassium channels, memory T cells, and multiple sclerosis

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Interleukin-13 is the key effector Th2 cytokine in ulcerative colitis that affects epithelial tight junctions, apoptosis, and cell restitution

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Targeting effector memory T cells with a selective peptide inhibitor of Kv1.3 channels for therapy of autoimmune diseases

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

T-bet upregulation and subsequent interleukin 12 stimulation are essential for induction of Th1 mediated immunopathology in Crohn's disease.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Potassium channels as therapeutic targets for autoimmune disorders

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

The voltage-gated Kv1.3 K(+) channel in effector memory T cells as new target for MS

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Modulation of Kv channel expression and function by TCR and costimulatory signals during peripheral CD4(+) lymphocyte differentiation

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

The transcription factor T-bet regulates mucosal T cell activation in experimental colitis and Crohn's disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

NFAT signaling: choreographing the social lives of cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Molecular properties and physiological roles of ion channels in the immune system

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Delineation of the clotrimazole/TRAM-34 binding site on the intermediate conductance calcium-activated potassium channel, IKCa1

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Up-regulation of the IKCa1 potassium channel during T-cell activation. Molecular mechanism and functional consequences

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Design of a potent and selective inhibitor of the intermediate-conductance Ca2+-activated K+ channel, IKCa1: a potential immunosuppressant

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Differential Ca2+ influx, KCa channel activity, and Ca2+ clearance distinguish Th1 and Th2 lymphocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

CD45RBhigh CD4+ T cells from IFN-gamma knockout mice do not induce wasting disease

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Functional diversity of helper T lymphocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

A critical role for transforming growth factor-beta but not interleukin 4 in the suppression of T helper type 1-mediated colitis by CD45RB(low) CD4+ T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Experimental granulomatous colitis in mice is abrogated by induction of TGF-beta-mediated oral tolerance

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Inhibition of Thl responses prevents inflammatory bowel disease in scid mice reconstituted with CD45RBhi CD4+ T cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

TH1 and TH2 cells: different patterns of lymphokine secretion lead to different functional properties

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

The voltage-gated Kv1.3 K+ channel in effector memory T cells as new target for MS

14 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Physiological roles of the intermediate conductance, Ca2+-activated potassium channel Kcnn4.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Disruption of the Gardos channel (KCa3.1) in mice causes subtle erythrocyte macrocytosis and progressive splenomegaly.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Histidine phosphorylation of the potassium channel KCa3.1 by nucleoside diphosphate kinase B is required for activation of KCa3.1 and CD4 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

RORgamma-expressing Th17 cells induce murine chronic intestinal inflammation via redundant effects of IL-17A and IL-17F.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

IL-17A directly inhibits TH1 cells and thereby suppresses development of intestinal inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0910133107

A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2824388

Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Th1-mediated intestinal inflammation in Crohn's disease may be induced by activation of lamina propria lymphocytes through synergistic stimulation of interleukin-12 and interleukin-18 without T cell receptor engagement

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Immunology. Decoding calcium signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20080610

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0910133107

1 reference

28 July 2017

0 references

1 reference

28 July 2017

1 reference