(Q53597450)

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Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

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1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease. (English)

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

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1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

Brigitta Stockinger

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Brigitta Stockinger

4

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Richard Flavell

3

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Richard A Flavell

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

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Richard J Hocking

2

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

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24 September 2006

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

Nature Immunology

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

1151-1156

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

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Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Experimental autoimmune encephalitis and inflammation in the absence of interleukin-12

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

IL-23 drives a pathogenic T cell population that induces autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Microbial lipopeptides induce the production of IL-17 in Th cells.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

IL-23 compensates for the absence of IL-12p70 and is essential for the IL-17 response during tuberculosis but is dispensable for protection and antigen-specific IFN-gamma responses if IL-12p70 is available

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

The transforming growth factor-beta family

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Reversal of acute and chronic synovial inflammation by anti-transforming growth factor beta

1 reference

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Transforming growth factor beta: the good, the bad, and the ugly

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Recovery from experimental allergic encephalomyelitis is TGF-beta dependent and associated with increases in CD4+LAP+ and CD4+CD25+ T cells.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Epicutaneously induced TGF-beta-dependent tolerance inhibits experimental autoimmune encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Latent TGF-beta1-transduced CD4+ T cells suppress the progression of allergic encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

A role for fungal {beta}-glucans and their receptor Dectin-1 in the induction of autoimmune arthritis in genetically susceptible mice

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Transforming growth factor-beta induces development of the T(H)17 lineage

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

A function for interleukin 2 in Foxp3-expressing regulatory T cells

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Immunological aspects of demyelinating diseases

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Passive transfer and labelling studies on the cell infiltrate in experimental allergic encephalomyelitis.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Interleukin-17.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

The influence of the proinflammatory cytokine, osteopontin, on autoimmune demyelinating disease

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Exacerbated tissue destruction in DSS-induced acute colitis of OPN-null mice is associated with downregulation of TNF-alpha expression and non-programmed cell death

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Collaborative induction of inflammatory responses by dectin-1 and Toll-like receptor 2.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance.

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

Of mice, men, and elephants: Mycobacterium tuberculosis cell envelope lipids and pathogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

21 January 2018

IL-12p35-deficient mice are susceptible to experimental autoimmune encephalomyelitis: evidence for redundancy in the IL-12 system in the induction of central nervous system autoimmune demyelination

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice: IL-12 responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of immune induction of collagen-induced arthritis in IL-17-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

The role of helper T cell subsets in autoimmune diseases

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Administration of neutralizing antibodies to interleukin-6 (IL-6) reduces experimental autoimmune encephalomyelitis and is associated with elevated levels of IL-6 bioactivity in central nervous system and circulation

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Lymphotoxin and tumor necrosis factor-alpha production by myelin basic protein-specific T cell clones correlates with encephalitogenicity

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Control of established experimental allergic encephalomyelitis by inhibition of tumor necrosis factor (TNF) activity within the central nervous system using monoclonal antibodies and TNF receptor-immunoglobulin fusion proteins

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Cutting edge: Attenuated experimental autoimmune encephalomyelitis in eta-1/osteopontin-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Eta-1 (osteopontin): an early component of type-1 (cell-mediated) immunity

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Osteopontin is not required for the development of Th1 responses and viral immunity

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Understanding the IL-23-IL-17 immune pathway

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Selective regulation of IL-10 signaling and function by zymosan

1 reference

https://api.crossref.org/works/10.1038%2FNI1391

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

1 reference

Europe PubMed Central

16 May 2018

http://europepmc.org/abstract/MED/16998492

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