(Q33676528)

24652288

28 July 2017

title

Regulation of fibroblast growth factor-inducible 14 (Fn14) expression levels via ligand-independent lysosomal degradation (English)

1 reference

28 July 2017

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

author name string

Sujatha Gurunathan

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Jeffrey A Winkles

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

Sankar Ghosh

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

language of work or name

English

0 references

publication date

20 March 2014

1 reference

24652288

28 July 2017

number of pages

13

1 reference

Journal of Biological Chemistry

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

volume

289

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

issue

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

page(s)

12976-12988

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

10 June 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4036313/fullTextXML

inferred from PubMed Central ID database lookup

cites work

TWEAK-independent Fn14 self-association and NF-κB activation is mediated by the C-terminal region of the Fn14 cytoplasmic domain

1 reference

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Antitumor activity of a humanized, bivalent immunotoxin targeting fn14-positive solid tumors

21 June 2018

1 reference

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Fibroblast growth factor inducible (Fn14)-specific antibodies concomitantly display signaling pathway-specific agonistic and antagonistic activity

21 June 2018

1 reference

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The HER2- and heregulin β1 (HRG)-inducible TNFR superfamily member Fn14 promotes HRG-driven breast cancer cell migration, invasion, and MMP9 expression

21 June 2018

1 reference

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The TWEAK receptor Fn14 is a therapeutic target in melanoma: immunotoxins targeting Fn14 receptor for malignant melanoma treatment

21 June 2018

1 reference

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The TWEAK/Fn14 pathway as an aggravating and perpetuating factor in inflammatory diseases: focus on inflammatory bowel diseases

21 June 2018

1 reference

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TWEAK/Fn14 pathway: an immunological switch for shaping tissue responses

21 June 2018

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Elevated fibroblast growth factor-inducible 14 expression promotes gastric cancer growth via nuclear factor-κB and is associated with poor patient outcome

21 June 2018

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A quantitative spatial proteomics analysis of proteome turnover in human cells

21 June 2018

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Development and characterization of a potent immunoconjugate targeting the Fn14 receptor on solid tumor cells

21 June 2018

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The Polycomb group protein EED couples TNF receptor 1 to neutral sphingomyelinase

21 June 2018

1 reference

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TWEAK and its receptor Fn14 in the synovium of patients with rheumatoid arthritis compared to psoriatic arthritis and its response to tumour necrosis factor blockade

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

TWEAK-FN14 signaling induces lysosomal degradation of a cIAP1-TRAF2 complex to sensitize tumor cells to TNFalpha.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

The TWEAK-Fn14 cytokine-receptor axis: discovery, biology and therapeutic targeting

21 June 2018

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CD40 ligation decreases its protein half-life at the cell surface

21 June 2018

1 reference

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TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease

21 June 2018

1 reference

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Cholesterol-dependent and -independent CD40 internalization and signaling activation in cardiovascular endothelial cells

21 June 2018

1 reference

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Identification of Fn14/TWEAK receptor as a potential therapeutic target in esophageal adenocarcinoma

21 June 2018

1 reference

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The alliance for cellular signaling plasmid collection: a flexible resource for protein localization studies and signaling pathway analysis

21 June 2018

1 reference

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TWEAK, via its receptor Fn14, is a novel regulator of mesenchymal progenitor cells and skeletal muscle regeneration

21 June 2018

1 reference

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Role of lipids and actin in the formation of clathrin-coated pits

21 June 2018

1 reference

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Increased fibroblast growth factor-inducible 14 expression levels promote glioma cell invasion via Rac1 and nuclear factor-kappaB and correlate with poor patient outcome

21 June 2018

1 reference

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Cytokine cooperation in renal tubular cell injury: the role of TWEAK.

21 June 2018

1 reference

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Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by atorvastatin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Endocytosis conducts the cell signaling orchestra

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

TWEAK attenuates the transition from innate to adaptive immunity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

TWEAK induces liver progenitor cell proliferation

21 June 2018

1 reference

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Multiple members of the TNF superfamily contribute to IFN-gamma-mediated inhibition of erythropoiesis

21 June 2018

1 reference

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Tweak induces mammary epithelial branching morphogenesis.

21 June 2018

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The tumor necrosis factor-like weak inducer of apoptosis (TWEAK)-fibroblast growth factor-inducible 14 (Fn14) signaling system regulates glioma cell survival via NFkappaB pathway activation and BCL-XL/BCL-W expression

21 June 2018

1 reference

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Compartmentalization of TNF receptor 1 signaling: internalized TNF receptosomes as death signaling vesicles

21 June 2018

1 reference

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Fibroblast growth factor-inducible-14 is induced in axotomized neurons and promotes neurite outgrowth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Induction of TNF receptor I-mediated apoptosis via two sequential signaling complexes

21 June 2018

1 reference

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21 June 2018

1 reference

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Dual role for TWEAK in angiogenic regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Multiple pathways of TWEAK-induced cell death

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Molecular ordering of the initial signaling events of CD95.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

A novel TNF receptor family member binds TWEAK and is implicated in angiogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Involvement of TWEAK in interferon gamma-stimulated monocyte cytotoxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

The Fn14 immediate-early response gene is induced during liver regeneration and highly expressed in both human and murine hepatocellular carcinomas

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

The mitogen-inducible Fn14 gene encodes a type I transmembrane protein that modulates fibroblast adhesion and migration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

TWEAK can induce cell death via endogenous TNF and TNF receptor 1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

TNF induces internalization of the p60 receptor and shedding of the p80 receptor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

CD40 molecules induce down-modulation and endocytosis of T cell surface T cell-B cell activating molecule/CD40-L. Potential role in regulating helper effector function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Perturbation of vesicular traffic with the carboxylic ionophore monensin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Brefeldin A causes disassembly of the Golgi complex and accumulation of secretory proteins in the endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

Brefeldin A: insights into the control of membrane traffic and organelle structure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4036313

TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis.

21 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563478

Tumor necrosis factor-like weak inducer of apoptosis is a mitogen for liver progenitor cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563478

Anti-TWEAK monoclonal antibodies reduce immune cell infiltration in the central nervous system and severity of experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563478

Expression of TWEAK and its receptor Fn14 in the multiple sclerosis brain: implications for inflammatory tissue injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563478

Proinflammatory effects of tumour necrosis factor-like weak inducer of apoptosis (TWEAK) on human gingival fibroblasts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563478

Internalization of CD40 regulates its signal transduction in vascular endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M114.563478

Bafilomycin A1, a specific inhibitor of vacuolar-type H(+)-ATPase, inhibits acidification and protein degradation in lysosomes of cultured cells

21 January 2018

1 reference

12 December 2020

Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells

1 reference

12 December 2020

TWEAK is expressed by glial cells, induces astrocyte proliferation and increases EAE severity

1 reference

12 December 2020

Down-regulation of CD20 on B cells upon CD40 activation

1 reference

12 December 2020

Tumor Necrosis Factor-Like Weak Inducer of Apoptosis-Induced Neurodegeneration

1 reference

12 December 2020

Protein degradation in isolated rat hepatocytes is inhibited by ammonia

1 reference

12 December 2020

Tumor necrosis factor-induced downregulation of its receptors in HeLa cells

1 reference

12 December 2020

TWEAK shall inherit the earth

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M114.563478

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json

10 June 2020

24652288

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24652288%20AND%20SRC:MED&resulttype=core&format=json