(Q33676747)

28 July 2017

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title

Mechanisms of tumor angiogenesis and therapeutic implications: angiogenesis inhibitors (English)

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28 July 2017

angiogenesis inhibitor

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Malonne H

1

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28 July 2017

Langer I

series ordinal

2

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28 July 2017

Kiss R

series ordinal

3

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28 July 2017

Atassi G

series ordinal

4

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28 July 2017

1 February 1999

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Clinical & Experimental Metastasis

28 July 2017

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28 July 2017

17

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28 July 2017

1-14

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28 July 2017

1

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https://scigraph.springernature.com/pub.10.1023/a:1026443925807

28 July 2017

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Transduction of retinoic acid and gamma-interferon signal for intercellular adhesion molecule-1 expression on human tumor cell lines: evidence for the late-acting involvement of protein kinase C inactivation.

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Antibodies to plasminogen activator inhibit human tumor metastasis

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12 December 2020

Integrins as dynamic regulators of vascular function.

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The nonluteal porcine ovary as a source of angiogenic activity

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12 December 2020

Prevention of metastasis by inhibition of the urokinase receptor

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12 December 2020

Secretion of metalloproteinases by stimulated capillary endothelial cells. II. Expression of collagenase and stromelysin activities is regulated by endogenous inhibitors.

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12 December 2020

Heparin-steroid conjugates: new angiogenesis inhibitors with antitumor activity in mice

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12 December 2020

Inhibitors of angiogenesis

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Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo

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12 December 2020

Recent insights into the pathogenesis of the proliferative lesion in rheumatoid arthritis

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12 December 2020

Alpha v integrins as receptors for tumor targeting by circulating ligands.

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12 December 2020

Angiogenesis mediated by soluble forms of E-selectin and vascular cell adhesion molecule-1.

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12 December 2020

Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats

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12 December 2020

Anti-angiogenic activity of triterpene acids

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12 December 2020

Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium

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12 December 2020

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12 December 2020

Inhibition of angiogenesis through modulation of collagen metabolism.

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12 December 2020

Suramin is a Potent Inhibitor of Vascular Endothelial Growth Factor. A Contribution to the Molecular Basis of its Antiangiogenic Action

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12 December 2020

Inhibition of angiogenesis and metastases of the Lewis-lung cell carcinoma by the quinoline-3-carboxamide, Linomide

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12 December 2020

Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice

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12 December 2020

Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent

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12 December 2020

[New inhibitors of tumor angiogenesis]

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12 December 2020

Suppression of angiogenesis by the antitumor agent titanocene dichloride

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12 December 2020

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

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12 December 2020

Cell adhesion molecules in angiogenesis

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12 December 2020

Dormancy of micrometastases: balanced proliferation and apoptosis in the presence of angiogenesis suppression

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12 December 2020

Angiogenesis correlates with vascular endothelial growth factor expression but not with Ki-ras oncogene activation in non-small cell lung carcinoma

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12 December 2020

Vascular endothelial growth factor increases urokinase receptor expression in vascular endothelial cells

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12 December 2020

Angiogenesis in cancer, vascular, rheumatoid and other disease

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12 December 2020

Hypoxic induction of human vascular endothelial growth factor expression through c-Src activation

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12 December 2020

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

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12 December 2020

Relationship between vasculogenesis, angiogenesis and haemopoiesis during avian ontogeny

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12 December 2020

Barriers to drug delivery in solid tumors

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12 December 2020

Inhibitors of urokinase reduce size of prostate cancer xenografts in severe combined immunodeficient mice

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12 December 2020

Structure and function of the urokinase receptor

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12 December 2020

A structure-activity analysis of antagonism of the growth factor and angiogenic activity of basic fibroblast growth factor by suramin and related polyanions

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12 December 2020

Complementation between urokinase-producing and receptor-producing cells in extracellular matrix degradation

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12 December 2020

Irsogladine is a potent inhibitor of angiogenesis

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12 December 2020

The matrix metalloproteinases and their inhibitors in pancreatic cancer. From molecular science to a clinical application

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12 December 2020

Negative regulation of hypoxia-inducible genes by the von Hippel-Lindau protein

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12 December 2020

Upregulation of urokinase receptor expression on migrating endothelial cells

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12 December 2020

Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis

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12 December 2020

A role of fibrinolytic activity in angiogenesis. Quantitative assay using in vitro method

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12 December 2020

Effects of novel and conventional anti-cancer agents on human endothelial permeability: influence of tumour secreted factors.

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12 December 2020

Tumor cell adhesion to the extracellular matrix and signal transduction mechanisms implicated in tumor cell motility, invasion and metastasis

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12 December 2020

A role for sialyl Lewis-X/A glycoconjugates in capillary morphogenesis

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12 December 2020

Angiogenesis inhibitor SR 25989 upregulates thrombospondin-1 expression in human vascular endothelial cells and foreskin fibroblasts

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12 December 2020

Signaling vascular morphogenesis and maintenance

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12 December 2020

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

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12 December 2020

Mechanisms of angiogenesis

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12 December 2020

Antiangiogenesis for cancer therapy

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12 December 2020

Endothelial proliferation in tumours and normal tissues: Continuous labelling studies

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12 December 2020

Thalidomide is an inhibitor of angiogenesis

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12 December 2020

Inhibition of angiogenesis by aurintricarboxylic acid

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12 December 2020

Suppression of pulmonary metastases of rat mammary cancer by recombinant urokinase plasminogen activator inhibitor

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12 December 2020

Inhibition of tumor growth and neovascularization by an anti-gastric ulcer agent, irsogladine.

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12 December 2020

Inhibition of angiogenesis by the matrix metalloprotease inhibitor N-[2R-2-(hydroxamidocarbonymethyl)-4-methylpentanoyl)]-L-tryptophan methylamide.

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12 December 2020

Suramin prevents neovascularisation and tumour growth through blocking of basic fibroblast growth factor activity

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12 December 2020

Identification of an Inhibitor of Neovascularization from Cartilage

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12 December 2020

Angiogenesis research yields new approaches to cancer treatment and prognosis

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12 December 2020

Potentiation of cytotoxic cancer therapies by TNP-470 alone and with other anti-angiogenic agents

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12 December 2020

Inhibition of endothelial cell proliferation by gamma-interferon

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12 December 2020

The fibrinolytic system. A key to tumor metastasis?

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12 December 2020

Matrix metalloproteinase inhibition as a novel anticancer strategy: a review with special focus on batimastat and marimastat

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12 December 2020

Dominant-negative inhibition of Flk-1 suppresses the growth of many tumor types in vivo.

1 reference

12 December 2020

Radicicol, a microbial cell differentiation modulator, inhibits in vivo angiogenesis

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12 December 2020

Tumor Growth and Neovascularization: An Experimental Model Using the Rabbit Cornea 2

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12 December 2020

Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels

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12 December 2020

Assays for angiogenesis: A review

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12 December 2020

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

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12 December 2020

A diaminoantraquinone inhibitor of angiogenesis

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12 December 2020

Tumor angiogenesis and the role of vascular cell integrin alphavbeta3.

1 reference

12 December 2020

A metalloproteinase inhibitor as an inhibitor of neovascularization

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12 December 2020

Inhibition of urokinase by 4-substituted benzo[b]thiophene-2-carboxamidines: an important new class of selective synthetic urokinase inhibitor

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12 December 2020

Inhibition of tumor growth in mice by an analogue of platelet factor 4 that lacks affinity for heparin and retains potent angiostatic activity.

1 reference

12 December 2020

Treatment of haemangioendotheliomas with alpha interferon

1 reference

12 December 2020

Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma

1 reference

12 December 2020

Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis

1 reference

12 December 2020

In vitro angiogenesis on the human amniotic membrane: requirement for basic fibroblast growth factor-induced proteinases.

1 reference

12 December 2020

Both v-Ha-Ras and v-Raf stimulate expression of the vascular endothelial growth factor in NIH 3T3 cells

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12 December 2020

In situ detection of tissue factor in vascular endothelial cells: correlation with the malignant phenotype of human breast disease

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12 December 2020

Systemic Amiloride Inhibits Experimentally Induced Neovascularization

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12 December 2020

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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12 December 2020

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

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12 December 2020

Potent, selective, orally active 3-oxo-1,4-benzodiazepine GPIIb/IIIa integrin antagonists

1 reference

12 December 2020

Up-regulation of vascular endothelial growth factor and its receptors in von Hippel-Lindau disease-associated and sporadic hemangioblastomas

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12 December 2020

A modified and convenient method for assessing tumor cell invasion and migration and its application to screening for inhibitors

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12 December 2020

Eriochrome Black T, structurally related to suramin, inhibits angiogenesis and tumor growth in vivo

1 reference

12 December 2020

FCE 27266, a sulfonic distamycin derivative, inhibits experimental and spontaneous lung and liver metastasis.

1 reference

12 December 2020

Addressing tumor blood vessels

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12 December 2020

Tumor-promoting phorbol esters induce angiogenesis in vitro

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12 December 2020

5,7-Dimethoxy-3-(4-pyridinyl)quinoline is a potent and selective inhibitor of human vascular beta-type platelet-derived growth factor receptor tyrosine kinase

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12 December 2020

In vivo paracrine interaction between urokinase and its receptor: effect on tumor cell invasion

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12 December 2020

Captopril inhibits tumour growth in a xenograft model of human renal cell carcinoma

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12 December 2020

Cyclosporine is angiostatic

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12 December 2020

Antitumor activity of FCE 26644 a new growth-factor complexing molecule.

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12 December 2020

Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis.

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12 December 2020

Prevention of prostate-cancer metastasis in vivo by a novel synthetic inhibitor of urokinase-type plasminogen activator (uPA).

1 reference

12 December 2020

Differentiation of endothelium.

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12 December 2020

Retinoids modulate endothelial cell production of matrix-degrading proteases and tissue inhibitors of metalloproteinases (TIMP)

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12 December 2020

Endostatin: an endogenous inhibitor of angiogenesis and tumor growth

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12 December 2020

Sequential loss of suppressor genes for three specific functions during in vivo carcinogenesis

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12 December 2020

Extrajunctional distribution of N-cadherin in cultured human endothelial cells

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12 December 2020

Platelet thrombospondin modulates endothelial cell adhesion, motility, and growth: a potential angiogenesis regulatory factor.

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12 December 2020

Angiopoietin-2, a natural antagonist for Tie2 that disrupts in vivo angiogenesis

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12 December 2020

Protamine is an inhibitor of angiogenesis

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12 December 2020

Tumor dormancy in vivo by prevention of neovascularization

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12 December 2020

Effect of matrix metalloproteinase inhibitor batimastat on breast cancer regrowth and metastasis in athymic mice

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12 December 2020

Inhibition of tumor-induced angiogenesis by the administration of recombinant interferon-gamma followed by a synthetic lipid-A subunit analogue (GLA-60)

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12 December 2020

1 reference

12 December 2020

Proteolytic balance and capillary morphogenesis

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12 December 2020

Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma

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12 December 2020

Membrane and matrix localization of proteinases: a common theme in tumor cell invasion and angiogenesis.

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12 December 2020

Acitretin decreases tumor cell-induced angiogenesis

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12 December 2020

Plasminogen activator and collagenase production by cultured capillary endothelial cells

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12 December 2020

Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele

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12 December 2020

Reduction of tumor blood flow by flavone acetic acid: a possible component of therapy.

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12 December 2020

The opposing effects of basic fibroblast growth factor and transforming growth factor beta on the regulation of plasminogen activator activity in capillary endothelial cells

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12 December 2020

Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutant

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12 December 2020

Heterozygous embryonic lethality induced by targeted inactivation of the VEGF gene

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12 December 2020

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin

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12 December 2020

Control of angiogenesis with synthetic heparin substitutes

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12 December 2020

Relationship of endothelial cell proliferation to tumor vascularity in human breast cancer

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12 December 2020

Antivascular approaches to solid tumour therapy: evaluation of tubulin binding agents

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12 December 2020

Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo.

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12 December 2020

Treating cancer by inhibiting angiogenesis: new hopes and potential pitfalls

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12 December 2020

Seminars in Medicine of the Beth Israel Hospital, Boston. Clinical applications of research on angiogenesis

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12 December 2020

Increased expression of the Mr 72,000 type IV collagenase in human colonic adenocarcinoma

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12 December 2020

Regulators of Angiogenesis

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12 December 2020

The urokinase inhibitor p-aminobenzamidine inhibits growth of a human prostate tumor in SCID mice

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12 December 2020

Suppression of VEGF-induced angiogenesis by the protein tyrosine kinase inhibitor, lavendustin A.

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12 December 2020

Cytostatic inhibition of endothelial cell growth by the angiogenesis inhibitor TNP-470 (AGM-1470).

1 reference

12 December 2020

Angiogenesis inhibition by minocycline

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12 December 2020

Mutant p53 potentiates protein kinase C induction of vascular endothelial growth factor expression.

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12 December 2020

Mutant ras oncogenes upregulate VEGF/VPF expression: implications for induction and inhibition of tumor angiogenesis.

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12 December 2020

Time-dependent vascular regression and permeability changes in established human tumor xenografts induced by an anti-vascular endothelial growth factor/vascular permeability factor antibody

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12 December 2020

Inhibition of stromelysin-1 (MMP-3) by P1'-biphenylylethyl carboxyalkyl dipeptides

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12 December 2020

Potentiation of the antiangiogenic ability of linomide by androgen ablation involves down-regulation of vascular endothelial growth factor in human androgen-responsive prostatic cancers.

1 reference

12 December 2020

Amiloride selectively inhibits the urokinase-type plasminogen activator

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12 December 2020

Integrins: versatility, modulation, and signaling in cell adhesion

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12 December 2020

Isolations of a cartilage factor that inhibits tumor neovascularization

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12 December 2020

Complete inhibition of angiogenesis and growth of microtumors by anti-vascular endothelial growth factor neutralizing antibody: novel concepts of angiostatic therapy from intravital videomicroscopy.

1 reference

12 December 2020

Wild-type p53 and v-Src exert opposing influences on human vascular endothelial growth factor gene expression

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12 December 2020

Dominant-negative and targeted null mutations in the endothelial receptor tyrosine kinase, tek, reveal a critical role in vasculogenesis of the embryo

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12 December 2020

Relation of vascular proliferation to tumor growth

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12 December 2020

Inhibition of angiogenesis and breast cancer in mice by the microtubule inhibitors 2-methoxyestradiol and taxol

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12 December 2020

A simple vessel for the culture of chicken embryos used in angiogenesis assays

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12 December 2020

Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor

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12 December 2020

Tumor angiogenesis: the role of oncogenes and tumor suppressor genes

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12 December 2020

Rodent pharmacokinetic and anti-tumor efficacy studies with a series of synthetic inhibitors of matrix metalloproteinases

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12 December 2020

The receptor tyrosine kinase TIE is required for integrity and survival of vascular endothelial cells.

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12 December 2020

Antiintegrin alpha v beta 3 blocks human breast cancer growth and angiogenesis in human skin

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12 December 2020

Integrin alpha v beta 3 rescues melanoma cells from apoptosis in three-dimensional dermal collagen

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12 December 2020

Control of tumor growth in animals by infusion of an angiogenesis inhibitor

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12 December 2020

Inhibition of angiogenesis and tumor growth by a synthetic laminin peptide, CDPGYIGSR-NH2

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12 December 2020

Signal transduction from the extracellular matrix

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12 December 2020

Extracellular matrix 6: role of matrix metalloproteinases in tumor invasion and metastasis.

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12 December 2020

Inhibition of angiogenesis in Kaposi's sarcoma by captopril

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12 December 2020

Inhibition of Angiogenesis and Murine Hemangioma Growth by Batimastat, a Synthetic Inhibitor of Matrix Metalloproteinases

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12 December 2020

Eriochrome black T inhibition of human skin collagenase, but not gelatinase, using both protein and synthetic substrates.

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12 December 2020

Inhibition of tumor angiogenesis as a strategy to circumvent acquired resistance to anti-cancer therapeutic agents

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12 December 2020

Consequences of angiogenesis for tumor progression, metastasis and cancer therapy.

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12 December 2020

Endothelial receptor tyrosine kinases involved in angiogenesis.

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12 December 2020

Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene

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12 December 2020

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12 December 2020

A 170-kDa membrane-bound protease is associated with the expression of invasiveness by human malignant melanoma cells

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12 December 2020

Definition of Two Angiogenic Pathways by Distinct alpha(v) Integrins

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12 December 2020

Thrombospondin-1 expression in bladder cancer: association with p53 alterations, tumor angiogenesis, and tumor progression

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12 December 2020

Tumor angiogenesis and metastasis--correlation in invasive breast carcinoma

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12 December 2020

Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.

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12 December 2020

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene.

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12 December 2020

Angiogenic and growth factors in human amnio-chorion and placenta

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12 December 2020

Identifiers

DOI

10.1023/A:1026443925807

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Dimensions Publication ID

28 July 2017

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