(Q33689595)

28 July 2017

title

Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion protein (English)

1 reference

28 July 2017

0 references

transmembrane protein

0 references

1 reference

Ramanujan Shankar Hegde

series ordinal

4

1 reference

28 July 2017

Neena S Rane

1

1 reference

28 July 2017

Oishee Chakrabarti

series ordinal

2

1 reference

28 July 2017

Lionel Feigenbaum

series ordinal

3

1 reference

28 July 2017

language of work or name

English

0 references

publication date

15 February 2010

1 reference

28 July 2017

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

Journal of Cell Biology

1 reference

28 July 2017

volume

188

1 reference

28 July 2017

issue

4

1 reference

28 July 2017

page(s)

515-526

1 reference

describes a project that uses

28 July 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2828915/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

A New Transgenic Mouse Model of Gerstmann-Straussler-Scheinker Syndrome Caused by the A117V Mutation of PRNP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Functional depletion of mahogunin by cytosolically exposed prion protein contributes to neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Prion protein biosynthesis and its emerging role in neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Reduced translocation of nascent prion protein during ER stress contributes to neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

The concept of translocational regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

The role of p58IPK in protecting the stressed endoplasmic reticulum

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Disease-associated prion protein oligomers inhibit the 26S proteasome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Developmental expression of PrP in the post-implantation embryo

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Substrate-specific translocational attenuation during ER stress defines a pre-emptive quality control pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

The surprising complexity of signal sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Conditions of endoplasmic reticulum stress favor the accumulation of cytosolic prion protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Proteasome dysfunction in mammalian aging: steps and factors involved

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Regulation of protein compartmentalization expands the diversity of protein function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Selective inhibition of cotranslational translocation of vascular cell adhesion molecule 1

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Protection from cytosolic prion protein toxicity by modulation of protein translocation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

The efficiency of protein compartmentalization into the secretory pathway

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Mitochondrial targeting and a novel transmembrane arrest of Alzheimer's amyloid precursor protein impairs mitochondrial function in neuronal cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Substrate-specific function of the translocon-associated protein complex during translocation across the ER membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Cotranslational partitioning of nascent prion protein into multiple populations at the translocation channel

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Wild-type PrP and a mutant associated with prion disease are subject to retrograde transport and proteasome degradation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Proteasomes and ubiquitin are involved in the turnover of the wild-type prion protein

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Substrate-specific regulation of the ribosome- translocon junction by N-terminal signal sequences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Transmissible and genetic prion diseases share a common pathway of neurodegeneration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

21 June 2018

Prion Protein Biology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

A transmembrane form of the prion protein in neurodegenerative disease

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Structure of the recombinant full-length hamster prion protein PrP(29-231): the N terminus is highly flexible

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

NMR structure of the mouse prion protein domain PrP(121-231)

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Signal sequence-dependent function of the TRAM protein during early phases of protein transport across the endoplasmic reticulum membrane

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

A two-step recognition of signal sequences determines the translocation efficiency of proteins.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Signal sequences. The limits of variation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Unusual topogenic sequence directs prion protein biogenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Epitope mapping of the Syrian hamster prion protein utilizing chimeric and mutant genes in a vaccinia virus expression system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Immunochemical, molecular genetic, and transmission studies on a case of Gerstmann-Straussler-Scheinker syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

A prion protein variant in a family with the telencephalic form of Gerstmann-Straussler-Scheinker syndrome

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation

21 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

A substrate-specific inhibitor of protein translocation into the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Regulation of protein topology by trans-acting factors at the endoplasmic reticulum

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Signal sequences control gating of the protein translocation channel in a substrate-specific manner

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Signal sequences: more than just greasy peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

A new PRNP mutation (G131V) associated with Gerstmann-Sträussler-Scheinker disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

NMR characterization of the full-length recombinant murine prion protein, mPrP(23-231).

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Mutational analysis of topological determinants in prion protein (PrP) and measurement of transmembrane and cytosolic PrP during prion infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

A Transmembrane Form of the Prion Protein Is Localized in the Golgi Apparatus of Neurons

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

A novel mutation (G114V) in the prion protein gene in a family with inherited prion disease

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2828915

Combinatorial Control of Prion Protein Biogenesis by the Signal Sequence and Transmembrane Domain

30 October 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200911115

21 January 2018

Identifiers

DOI

10.1083/JCB.200911115

1 reference

28 July 2017

1 reference

28 July 2017

1 reference