(Q33690295)

28 July 2017

Transgenic cardiac-targeted overexpression of human thymidylate kinase (English)

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28 July 2017

2 references

ChEBI release 2020-05-28

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1 reference

James J Kohler

1

1 reference

28 July 2017

Seyed H Hosseini

2

1 reference

28 July 2017

Ioan Cucoranu

3

1 reference

28 July 2017

Olga Zhelyabovska

4

1 reference

28 July 2017

Elgin Green

5

1 reference

28 July 2017

Kristopher Ivey

6

1 reference

28 July 2017

Allison Abuin

7

1 reference

28 July 2017

Earl Fields

8

1 reference

28 July 2017

Amy Hoying

9

1 reference

28 July 2017

Rodney Russ

10

1 reference

28 July 2017

Robert Santoianni

11

1 reference

28 July 2017

C Michael Raper

12

1 reference

28 July 2017

Qinglin Yang

13

1 reference

28 July 2017

Arnon Lavie

14

1 reference

28 July 2017

William Lewis

15

1 reference

28 July 2017

11 January 2010

1 reference

full work available at URL

28 July 2017

https://europepmc.org/articles/pmc2829097?pdf=render

1 reference

26 April 2024

https://api.unpaywall.org/v2/10.1038/labinvest.2009.146?email=unpaywall_01@example.com

published in

Laboratory Investigation

1 reference

28 July 2017

90

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28 July 2017

383-390

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28 July 2017

3

1 reference

https://api.unpaywall.org/v2/10.1038/labinvest.2009.146?email=unpaywall_01@example.com

28 July 2017

1 reference

26 April 2024

access restriction status

open access

1 reference

inferred from online access status

exact match

https://scigraph.springernature.com/pub.10.1038/labinvest.2009.146

0 references

cites work

Murine cardiac mtDNA: effects of transgenic manipulation of nucleoside phosphorylation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Cardiac-targeted transgenic mutant mitochondrial enzymes: mtDNA defects, antiretroviral toxicity and cardiomyopathy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Absence of a universal mechanism of mitochondrial toxicity by nucleoside analogs

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Maintaining precursor pools for mitochondrial DNA replication

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Targeted transgenic overexpression of mitochondrial thymidine kinase (TK2) alters mitochondrial DNA (mtDNA) and mitochondrial polypeptide abundance: transgenic TK2, mtDNA, and antiretrovirals

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Decreased mtDNA, oxidative stress, cardiomyopathy, and death from transgenic cardiac targeted human mutant polymerase gamma.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mitochondrial deoxynucleotide pool sizes in mouse liver and evidence for a transport mechanism for thymidine monophosphate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

DNA precursor metabolism and genomic stability

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Antiretroviral nucleosides, deoxynucleotide carrier and mitochondrial DNA: evidence supporting the DNA pol gamma hypothesis.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mouse models of mitochondrial dysfunction and heart failure

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Structural requirements for efficient phosphorylation of nucleotide analogs by human thymidylate kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

The mitochondrial transporter family (SLC25): physiological and pathological implications

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mitochondrial toxicity of nrti antiviral drugs: an integrated cellular perspective

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mitochondrial DNA replication: what we know

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Nucleoside analogues and nucleobases in cancer treatment.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Phosphorylation of nucleosides and nucleoside analogs by mammalian nucleoside monophosphate kinases

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mitochondrial neurogastrointestinal encephalomyopathy: an autosomal recessive disorder due to thymidine phosphorylase mutations

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Remodeling the cardiac sarcomere using transgenesis

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Cardiac dysfunction occurs in the HIV-1 transgenic mouse treated with zidovudine

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Human dTMP kinase: gene expression and enzymatic activity coinciding with cell cycle progression and cell growth

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

In vivo definition of a cardiac specific promoter and its potential utility in remodeling the heart

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Inhibition of thymidine kinase activity in liver and hepatomas by TTP and d-CTP.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

The in vitro and in vivo anti-retrovirus activity, and intracellular metabolism of 3'-azido-2',3'-dideoxythymidine and 2',3'-dideoxycytidine are highly dependent on the cell species

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mitochondrial myopathy caused by long-term zidovudine therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Mouse L cell mitochondrial DNA molecules are selected randomly for replication throughout the cell cycle

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829097

Transgenic expression of the deoxynucleotide carrier causes mitochondrial damage that is enhanced by NRTIs for AIDS.

21 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.146

Mitochondrial:nuclear DNA ratios in peripheral blood cells from human immunodeficiency virus (HIV)-infected patients who received selected HIV antiretroviral drug regimens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.146

Combined antiretroviral therapy causes cardiomyopathy and elevates plasma lactate in transgenic AIDS mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.146

Transgenic mitochondrial superoxide dismutase and mitochondrially targeted catalase prevent antiretroviral-induced oxidative stress and cardiomyopathy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.146

Defective mitochondrial DNA replication and NRTIs: pathophysiological implications in AIDS cardiomyopathy

21 January 2018

1 reference

12 December 2020

Enzyme Inhibition by Phosphonate Analogues of dTTP

1 reference

12 December 2020

Expression and substrate specificities of human thymidine kinase 1, thymidine kinase 2 and deoxycytidine kinase

1 reference

12 December 2020

Deoxynucleotide pools and DNA synthesis in resting and PHA-stimulated human lymphocytes treated with mutagens

1 reference

12 December 2020

The bottleneck in AZT activation

1 reference

12 December 2020

Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation

1 reference

12 December 2020

Mitochondrial neurogastrointestinal encephalomyopathy: An autosomal recessive disorder due to thymidine phosphorylase mutations

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.2009.146

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/LABINVEST.2009.146

1 reference

Dimensions Publication ID

28 July 2017

0 references

1 reference

28 July 2017

1 reference