(Q33691654)

28 July 2017

title

Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis (English)

1 reference

28 July 2017

1 reference

1 reference

1 reference

4

Robson Q. Monteiro

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

12 July 2024

author name string

Daniella M. Mizurini

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

12 July 2024

Ivo M. B. Francischetti

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

12 July 2024

John F. Andersen

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

12 July 2024

language of work or name

English

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20838739

12 July 2024

publication date

13 September 2010

1 reference

full work available at URL

28 July 2017

https://europepmc.org/articles/pmc2996477?pdf=render

file format

Portable Document Format

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

https://europepmc.org/articles/PMC2996477

12 July 2024

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

https://europepmc.org/articles/PMC2996477?pdf=render

12 July 2024

file format

Portable Document Format

online access status

open access

content deliverer

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

https://doi.org/10.1160/th10.1160/th10-03-0186

12 July 2024

online access status

open access

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A20838739

Thrombosis and Haemostasis

12 July 2024

published in

1 reference

28 July 2017

volume

104

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28 July 2017

issue

6

1 reference

28 July 2017

page(s)

1116-1123

1 reference

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis

28 July 2017

cites work

1 reference

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Role of tissue factor in cancer

21 June 2018

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Blood coagulation, inflammation, and malaria

21 June 2018

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Ixolaris binding to factor X reveals a precursor state of factor Xa heparin-binding exosite

21 June 2018

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Intrinsic pathway of coagulation and arterial thrombosis

21 June 2018

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The intrinsic pathway of coagulation: a target for treating thromboembolic disease?

21 June 2018

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Factor IXa inhibitors as novel anticoagulants

21 June 2018

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On the molecular mechanisms for the highly procoagulant pattern of C6 glioma cells

21 June 2018

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Defective thrombus formation in mice lacking coagulation factor XII

21 June 2018

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Structural determinants of factor IX(a) binding in nitrophorin 2, a lipocalin inhibitor of the intrinsic coagulation pathway

21 June 2018

1 reference

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Effects of factor IX or factor XI deficiency on ferric chloride-induced carotid artery occlusion in mice

21 June 2018

1 reference

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The role of salivary lipocalins in blood feeding by Rhodnius prolixus

21 June 2018

1 reference

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Ixolaris: a factor Xa heparin-binding exosite inhibitor

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Ixolaris, a novel recombinant tissue factor pathway inhibitor (TFPI) from the salivary gland of the tick, Ixodes scapularis: identification of factor X and factor Xa as scaffolds for the inhibition of factor VIIa/tissue factor complex.

21 June 2018

1 reference

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Interaction of bothrojaracin with prothrombin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Activation of factor IX by factor XIa.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Kinetics and equilibria in ligand binding by nitrophorins 1-4: evidence for stabilization of a nitric oxide-ferriheme complex through a ligand-induced conformational trap

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Biochemistry and physiology of blood coagulation.

21 June 2018

1 reference

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Targeted inhibition of intrinsic coagulation limits cerebral injury in stroke without increasing intracerebral hemorrhage

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Nitrophorin-2: a novel mixed-type reversible specific inhibitor of the intrinsic factor-X activating complex.

21 June 2018

1 reference

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Biochemical and pharmacological properties of SANORG 32701. Comparison with the "synthetic pentasaccharide' (SR 90107/ORG 31540) and standard heparin

21 June 2018

1 reference

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High affinity histamine-binding and antihistaminic activity of the salivary nitric oxide-carrying heme protein (nitrophorin) of Rhodnius prolixus.

21 June 2018

1 reference

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Purification and characterization of prolixin S (nitrophorin 2), the salivary anticoagulant of the blood-sucking bug Rhodnius prolixus

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Interpreting complex binding kinetics from optical biosensors: a comparison of analysis by linearization, the integrated rate equation, and numerical integration.

21 June 2018

1 reference

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Prolixin-S and Prolixin-G; Two Anticoagulants from Rhodnius prolixus Stål

21 June 2018

1 reference

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Antithrombotic properties of Ixolaris, a potent inhibitor of the extrinsic pathway of the coagulation cascade.

21 June 2018

1 reference

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Tissue factor and thrombosis: The clot starts here.

14 July 2018

1 reference

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New oral anticoagulant drugs in cardiovascular disease.

30 October 2018

1 reference

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Molecular diversity of anticoagulants from haematophagous animals.

30 October 2018

1 reference

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An algal sulfated galactan has an unusual dual effect on venous thrombosis due to activation of factor XII and inhibition of the coagulation proteases.

30 October 2018

1 reference

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In vivo response to vascular injury in the absence of factor IX: examination in factor IX knockout mice

30 October 2018

1 reference

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Pharmacokinetics and anticoagulant properties of the factor VIIa-tissue factor inhibitor recombinant Nematode Anticoagulant Protein c2 following subcutaneous administration in man. Dependence on the stoichiometric binding to circulating factor X.

30 October 2018

1 reference

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Bothrojaracin, a proexosite I ligand, inhibits factor Va-accelerated prothrombin activation.

30 October 2018

1 reference

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The insect salivary protein, prolixin-S, inhibits factor IXa generation and Xase complex formation in the blood coagulation pathway.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Antithrombotic efficacy of a novel murine antihuman factor IX antibody in rats.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Reversible binding of nitric oxide by a salivary heme protein from a bloodsucking insect.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2996477

Pharmacokinetics and pharmacodynamics of a humanized monoclonal antibody to factor IX in cynomolgus monkeys

30 October 2018

1 reference

12 December 2020

Inhibition of arterial thrombosis by a soluble tissue factor mutant and active site-blocked factors IXa and Xa in the guinea pig

1 reference

12 December 2020

Effect of 1-methyl-2-mercapto-5-(3-pyridyl)-imidazole (KC-6141), an anti-aggregating compound, on experimental thrombosis in rats

1 reference

12 December 2020

Assembly of the intrinsic factor X activating complex--interactions between factor IXa, factor VIIIa and phospholipid

1 reference

12 December 2020

The characterisation of thrombus development in an improved model of arterio-venous shunt thrombosis in the rat and the effects of recombinant desulphatohirudin (CGP 39393), heparin, and iloprost

1 reference

12 December 2020

Photochemically induced thrombosis model in rat femoral artery and evaluation of effects of heparin and tissue-type plasminogen activator with use of this model

1 reference

12 December 2020

Purification, characterization and cDNA cloning of a novel anticoagulant of the intrinsic pathway, (prolixin-S) from salivary glands of the blood sucking bug, Rhodnius prolixus

1 reference

12 December 2020

Emerging anticoagulants for the treatment of venous thromboembolism

1 reference

12 December 2020

Heparin and low-molecular-weight heparin

1 reference

12 December 2020

Identifiers

DOI

10.1160/TH10-03-0186

1 reference

10.1160/TH10.1160/TH10-03-0186

28 July 2017

1 reference

National Center for Biotechnology Information

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=20838739

12 July 2024

1 reference

28 July 2017

1 reference