(Q33691825)

28 July 2017

title

Gene expression in lung and liver after intravenous infusion of polyethylenimine complexes of Sleeping Beauty transposons (English)

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28 July 2017

4

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28 July 2017

8

Perry B Hackett

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28 July 2017

7

R Scott McIvor

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28 July 2017

6

Lalitha R Belur

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28 July 2017

Kelly M Podetz-Pedersen

series ordinal

1

object named as

Kelly M Podetz-Pedersen

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28 July 2017

Jason B Bell

2

1 reference

28 July 2017

Terry W J Steele

series ordinal

3

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28 July 2017

W Thomas Shier

series ordinal

5

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28 July 2017

language of work or name

1 reference

1 February 2010

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28 July 2017

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28 July 2017

volume

21

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28 July 2017

issue

2

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28 July 2017

page(s)

210-220

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Nanocapsule-delivered Sleeping Beauty mediates therapeutic Factor VIII expression in liver sinusoidal endothelial cells of hemophilia A mice

28 July 2017

cites work

1 reference

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Systemic correction of storage disease in MPS I NOD/SCID mice using the sleeping beauty transposon system

21 June 2018

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Preferential delivery of the Sleeping Beauty transposon system to livers of mice by hydrodynamic injection

21 June 2018

1 reference

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Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy

21 June 2018

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Hydrodynamic gene delivery to the pig liver via an isolated segment of the inferior vena cava

21 June 2018

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Gene therapy for mucopolysaccharidosis

21 June 2018

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Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses

21 June 2018

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Synthetic PEGylated glycoproteins and their utility in gene delivery

21 June 2018

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New therapeutic options for lysosomal storage disorders: enzyme replacement, small molecules and gene therapy

21 June 2018

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Cell and gene-based therapies for the lysosomal storage diseases

21 June 2018

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21 June 2018

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

21 June 2018

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Sustained FVIII expression and phenotypic correction of hemophilia A in neonatal mice using an endothelial-targeted sleeping beauty transposon

21 June 2018

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RNA as a source of transposase for Sleeping Beauty-mediated gene insertion and expression in somatic cells and tissues

21 June 2018

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Integration site selection by HIV-based vectors in dividing and growth-arrested IMR-90 lung fibroblasts.

21 June 2018

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Somatic integration of an oncogene-harboring Sleeping Beauty transposon models liver tumor development in the mouse

21 June 2018

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Genome-wide analysis of retroviral DNA integration

21 June 2018

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Gene transfer for hemophilia: can therapeutic efficacy in large animals be safely translated to patients?

21 June 2018

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Sleeping beauty transposon-mediated gene therapy for prolonged expression

21 June 2018

1 reference

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Awakening gene therapy with Sleeping Beauty transposons

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

A two-stage poly(ethylenimine)-mediated cytotoxicity: implications for gene transfer/therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Thermostability of firefly luciferases affects efficiency of detection by in vivo bioluminescence

21 June 2018

1 reference

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Sleeping Beauty-mediated down-regulation of huntingtin expression by RNA interference.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Promoter trapping reveals significant differences in integration site selection between MLV and HIV vectors in primary hematopoietic cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Retroviral DNA integration: ASLV, HIV, and MLV show distinct target site preferences

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Integration and long-term expression in xenografted human glioblastoma cells using a plasmid-based transposon system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Endothelial targeting of the Sleeping Beauty transposon within lung

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Excision of Sleeping Beauty transposons: parameters and applications to gene therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Gene therapy for lysosomal storage diseases: the lessons and promise of animal models

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Sleeping beauty transposition: biology and applications for molecular therapy

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Hydroporation as the mechanism of hydrodynamic delivery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Gene transfer into genomes of human cells by the sleeping beauty transposon system.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Sustainable correction of junctional epidermolysis bullosa via transposon-mediated nonviral gene transfer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Transcription start regions in the human genome are favored targets for MLV integration

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

AAV serotype 2 vectors preferentially integrate into active genes in mice

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

AAV-mediated factor IX gene transfer to skeletal muscle in patients with severe hemophilia B.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Gene therapy for the lysosomal storage disorders.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

HIV-1 integration in the human genome favors active genes and local hotspots

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Side-effects of a systemic injection of linear polyethylenimine-DNA complexes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Somatic integration and long-term transgene expression in normal and haemophilic mice using a DNA transposon system

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

PEGylated DNA/transferrin-PEI complexes: reduced interaction with blood components, extended circulation in blood and potential for systemic gene delivery

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Molecular reconstruction of Sleeping Beauty, a Tc1-like transposon from fish, and its transposition in human cells

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Direct comparison of hepatocyte-specific expression cassettes following adenoviral and nonviral hydrodynamic gene transfer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

AAV vector integration sites in mouse hepatocellular carcinoma.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Pig liver gene therapy by noninvasive interventionist catheterism.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Naked plasmid DNA transfer to the porcine liver using rapid injection with large volume

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Dynamic gene expression after systemic delivery of plasmid DNA as determined by in vivo bioluminescence imaging.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Combinatorial antiangiogenic gene therapy by nonviral gene transfer using the sleeping beauty transposon causes tumor regression and improves survival in mice bearing intracranial human glioblastoma

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Mechanistic studies on aggregation of polyethylenimine-DNA complexes and its prevention

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Hydrodynamic liver gene transfer mechanism involves transient sinusoidal blood stasis and massive hepatocyte endocytic vesicles.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Phenotypic correction and long-term expression of factor VIII in hemophilic mice by immunotolerization and nonviral gene transfer using the Sleeping Beauty transposon system

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Insertion of retroviral vectors in NOD/SCID repopulating human peripheral blood progenitor cells occurs preferentially in the vicinity of transcription start regions and in introns

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Insulin expression in livers of diabetic mice mediated by hydrodynamics-based administration

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Gene insertion and long-term expression in lung mediated by the Sleeping Beauty transposon system

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

In vivo correction of murine tyrosinemia type I by DNA-mediated transposition.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Development of catheter-based procedures for transducing the isolated rabbit liver with plasmid DNA.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Transposition from a gutless adeno-transposon vector stabilizes transgene expression in vivo

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Fending off decay: a combinatorial approach in intact cells for identifying mRNA stability elements

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Metabolic instability of plasmid DNA in the cytosol: a potential barrier to gene transfer

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Hydrodynamics-based transfection in animals by systemic administration of plasmid DNA.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829452

Low-volume hydrodynamic gene delivery to the rat liver via an isolated segment of the inferior vena cava: efficiency, cardiovascular response and intrahepatic vascular dynamics

30 October 2018

1 reference

12 December 2020

Systemic linear polyethylenimine (L-PEI)-mediated gene delivery in the mouse

1 reference

12 December 2020

Cell-selective intracellular delivery of a foreign enzyme to endothelium in vivo using vascular immunotargeting

1 reference

12 December 2020

In vivo imaging of NF-kappa B activity

1 reference

12 December 2020

Identifiers

DOI

10.1089/HUM.2009.128

1 reference

28 July 2017

1 reference

28 July 2017

1 reference