(Q33693709)

28 July 2017

title

Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia (English)

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28 July 2017

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skeletal muscle cancer

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Troels Marstrand

6

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Iain J Gallagher

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Iain J Gallagher

2

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James A Timmons

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James A Timmons

11

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author name string

Nathan A Stephens

1

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28 July 2017

Olav Rooyackers

3

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28 July 2017

Richard J Skipworth

4

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28 July 2017

Ben H Tan

5

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28 July 2017

James A Ross

7

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28 July 2017

Denis C Guttridge

8

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28 July 2017

Lars Lundell

9

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28 July 2017

Kenneth C Fearon

10

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28 July 2017

publication date

15 January 2010

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28 July 2017

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28 July 2017

volume

2

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28 July 2017

issue

1

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28 July 2017

page(s)

1

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https://scigraph.springernature.com/pub.10.1186/gm122

28 July 2017

exact match

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cites work

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A Ca(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions

28 July 2018

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28 July 2018

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Dysregulation of mitochondrial dynamics and the muscle transcriptome in ICU patients suffering from sepsis induced multiple organ failure

28 July 2018

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Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscle

28 July 2018

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Gene expression profiling in human skeletal muscle during recovery from eccentric exercise

28 July 2018

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FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Human skeletal muscle atrophy in amyotrophic lateral sclerosis reveals a reduction in Akt and an increase in atrogin-1.

28 July 2018

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Modulation of extracellular matrix genes reflects the magnitude of physiological adaptation to aerobic exercise training in humans

28 July 2018

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Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy

28 July 2018

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28 July 2018

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28 July 2018

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The role of calcium and calcium/calmodulin-dependent kinases in skeletal muscle plasticity and mitochondrial biogenesis

28 July 2018

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Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression

28 July 2018

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28 July 2018

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28 July 2018

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Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

28 July 2018

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Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

28 July 2018

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Identification of ubiquitin ligases required for skeletal muscle atrophy

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Significance analysis of microarrays applied to the ionizing radiation response

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

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28 July 2018

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Substrate availability limits human skeletal muscle oxidative ATP regeneration at the onset of ischemic exercise

28 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation

28 July 2018

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Prognostic effect of weight loss prior to chemotherapy in cancer patients. Eastern Cooperative Oncology Group

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Protein synthesis in muscle measured in vivo in cachectic patients with cancer

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Increased expression of inflammatory pathway genes in skeletal muscle during surgery.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Regulation of clock-controlled genes in mammals

30 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Suppression of Tie-1 in endothelial cells in vitro induces a change in the genome-wide expression profile reflecting an inflammatory function

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Downstream of Akt: FoxO3 and mTOR in the regulation of autophagy in skeletal muscle

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Evidence for the involvement of CaMKII and AMPK in Ca2+-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Coordinate activation of autophagy and the proteasome pathway by FoxO transcription factor.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Molecular biomarkers monitoring human skeletal muscle fibres and microvasculature following long-term bed rest with and without countermeasures.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Ubiquitin ligases MuRF1 and MAFbx in human skeletal muscle atrophy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Muscle atrophy and hypertrophy signaling in patients with chronic obstructive pulmonary disease

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Increased expression of proteasome subunits in skeletal muscle of cancer patients with weight loss.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Treatment of cultured myotubes with the calcium ionophore A23187 increases proteasome activity via a CaMK II-caspase-calpain-dependent mechanism.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Redox regulation of the calcium/calmodulin-dependent protein kinases.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Disuse atrophy and exercise rehabilitation in humans profoundly affects the expression of genes associated with the regulation of skeletal muscle mass.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Studies on apoptosis and fibrosis in skeletal musculature: a comparison of heart failure patients with and without cardiac cachexia

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Increased muscle proteasome activity correlates with disease severity in gastric cancer patients

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Cachexia in cancer patients

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Skeletal muscle mRNA levels for cathepsin B, but not components of the ubiquitin-proteasome pathway, are increased in patients with lung cancer referred for thoracotomy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

What do we really know about the ubiquitin-proteasome pathway in muscle atrophy?

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Effect of endurance exercise training on Ca2+ calmodulin-dependent protein kinase II expression and signalling in skeletal muscle of humans

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2829926

Lysosomal enzyme activity in muscle tissue from patients with malignant tumor

30 October 2018

1 reference

12 December 2020

Nutritional support of the cancer patient

1 reference

12 December 2020

Interleukin-6 production by contracting human skeletal muscle: autocrine regulation by IL-6

1 reference

12 December 2020

Activity of the Akt-dependent anabolic and catabolic pathways in muscle and liver samples in cancer-related cachexia

1 reference

12 December 2020

Increased muscle ubiquitin mRNA levels in gastric cancer patients

1 reference

12 December 2020

Total parenteral nutrition as an adjunct to chemotherapy of metastatic colorectal cancer

1 reference

12 December 2020

Identifiers

DOI

10.1186/GM122

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Dimensions Publication ID

28 July 2017

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28 July 2017

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