(Q33696554)

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Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge.

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19 January 2020

Apurinic/apyrimidinic endonuclease 2 is necessary for normal B cell development and recovery of lymphoid progenitors after chemotherapeutic challenge (English)

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19 January 2020

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Jeroen E Guikema

1

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19 January 2020

Yusaku Nakabeppu

7

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19 January 2020

Carol E. Schrader

8

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19 January 2020

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Rachel M Gerstein

2

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19 January 2020

Erin K Linehan

3

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19 January 2020

Erin K Cloherty

4

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19 January 2020

Eric Evan-Browning

5

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19 January 2020

Daisuke Tsuchimoto

6

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19 January 2020

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12 January 2011

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19 January 2020

Journal of Immunology

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19 January 2020

186

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19 January 2020

1943-1950

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19 January 2020

4

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19 January 2020

Hematopoietic stem cell quiescence promotes error-prone DNA repair and mutagenesis

1 reference

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14 July 2018

Rationally designed pharmacogenomic treatment using concurrent capecitabine and radiotherapy for glioblastoma; gene expression profiles associated with outcome

1 reference

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14 July 2018

p53-mediated hematopoietic stem and progenitor cell competition.

1 reference

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14 July 2018

DNA mismatch repair (MMR)-dependent 5-fluorouracil cytotoxicity and the potential for new therapeutic targets.

1 reference

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14 July 2018

V(D)J recombination deficiencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Role of PCNA-dependent stimulation of 3'-phosphodiesterase and 3'-5' exonuclease activities of human Ape2 in repair of oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Fixing DNA breaks during class switch recombination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Regulation of immunoglobulin light-chain recombination by the transcription factor IRF-4 and the attenuation of interleukin-7 signaling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Hematopoietic stem cell aging and self-renewal

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Base-excision repair of oxidative DNA damage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

A dominant-negative form of the major human abasic endonuclease enhances cellular sensitivity to laboratory and clinical DNA-damaging agents

1 reference

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14 July 2018

Hematopoietic dysfunction in a mouse model for Fanconi anemia group D1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Human Ape2 protein has a 3'-5' exonuclease activity that acts preferentially on mismatched base pairs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Mechanism and control of V(D)J recombination at the immunoglobulin heavy chain locus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Cell intrinsic alterations underlie hematopoietic stem cell aging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Mitochondria, oxidants, and aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Repair and genetic consequences of endogenous DNA base damage in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Bone marrow microenvironmental changes underlie reduced RAG-mediated recombination and B cell generation in aged mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Developmental separation of V(D)J recombinase expression and initiation of IgH recombination in B lineage progenitors in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

B lineage-specific regulation of V(D)J recombinase activity is established in common lymphoid progenitors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Peripheral B cell selection and homeostasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

The role of DNA breaks in genomic instability and tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Characterization of the genomic structure and expression of the mouse Apex2 gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Apoptosis and its modulation during B lymphopoiesis in mouse bone marrow

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Neonatal lethality with abnormal neurogenesis in mice deficient in DNA polymerase beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

The role of apoptosis in the regulation of hematopoietic stem cells: Overexpression of Bcl-2 increases both their number and repopulation potential

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

DNA ligase I is required for fetal liver erythropoiesis but is not essential for mammalian cell viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

The regulated expression of B lineage associated genes during B cell differentiation in bone marrow and fetal liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Bcl-2 and Bcl-x: regulatory switches for lymphoid death and survival

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

DNA strand breaks produced by oxidative stress in mammalian cells exhibit 3'-phosphoglycolate termini.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

14 July 2018

A distinctive DNA damage response in human hematopoietic stem cells reveals an apoptosis-independent role for p53 in self-renewal.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Systemic signals regulate ageing and rejuvenation of blood stem cell niches.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

DNA repair pathways involved in repair of lesions induced by 5-fluorouracil and its active metabolite FdUMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Altered gene expression profiles and higher frequency of spontaneous DNA strand breaks in APEX2-null thymus.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Role of hematopoietic microenvironment in prolonged impairment of B cell regeneration in age-related stromal-cell-impaired SAMP1 mouse: effects of a single dose of 5-fluorouracil

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Growth retardation and dyslymphopoiesis accompanied by G2/M arrest in APEX2-null mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Repopulating defect of mismatch repair–deficient hematopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Determinants in nuclease specificity of Ape1 and Ape2, human homologues of Escherichia coli exonuclease III.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

xid mice reveal the interplay of homeostasis and Bruton's tyrosine kinase-mediated selection at multiple stages of B cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4041036

30 October 2018

Comparative pharmacokinetic analysis of 5-fluorouracil and its major metabolite 5-fluoro-5,6-dihydrouracil after conventional and reduced test dose in cancer patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/21228350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Second human protein with homology to the Escherichia coli abasic endonuclease exonuclease III

1 reference

https://pubmed.ncbi.nlm.nih.gov/21228350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional isolation and characterization of human hematopoietic stem cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/21228350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endocrinology of aging

1 reference

https://pubmed.ncbi.nlm.nih.gov/21228350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impaired ability of bone marrow stromal cells to support B-lymphopoiesis with age

1 reference

https://pubmed.ncbi.nlm.nih.gov/21228350

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.1002422

1 reference

Europe PubMed Central

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19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21228350%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21228350%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

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