(Q33707949)

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A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro

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21 March 2020

A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro (English)

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21 March 2020

Kenichiro Motomura

1

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21 March 2020

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21 March 2020

Takeshi Nagamatsu

10

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Takeshi Nagamatsu

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21 March 2020

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Naoko Okada

2

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21 March 2020

Hideaki Morita

3

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21 March 2020

Mariko Hara

4

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21 March 2020

Masato Tamari

5

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21 March 2020

Keisuke Orimo

6

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21 March 2020

Go Matsuda

7

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21 March 2020

Ken-Ichi Imadome

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21 March 2020

Akio Matsuda

9

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21 March 2020

Mikiya Fujieda

11

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21 March 2020

Haruhiko Sago

12

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21 March 2020

Kenji Matsumoto

14

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21 March 2020

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19 May 2017

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21 March 2020

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21 March 2020

12

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21 March 2020

5

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21 March 2020

e0177994

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21 March 2020

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Creative Commons Attribution 4.0 International

19 May 2017

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April 2022 Public Data File from Crossref

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0 references

Notch1 controls development of the extravillous trophoblast lineage in the human placenta.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Rho kinase inhibitor enables cell-based therapy for corneal endothelial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Toll-like receptor profiling of seven trophoblast cell lines warrants caution for translation to primary trophoblasts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Alpha or beta human chorionic gonadotropin knockdown decrease BeWo cell fusion by down-regulating PKA and CREB activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

ADAM12-directed ectodomain shedding of E-cadherin potentiates trophoblast fusion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

A PKA-ezrin-Cx43 signaling complex controls gap junction communication and thereby trophoblast cell fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Hydroxychloroquine restores trophoblast fusion affected by antiphospholipid antibodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Cell fusion mediates dramatic alterations in the actin cytoskeleton, focal adhesions, and E-cadherin in trophoblastic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Intermediate conductance Ca2+-activated K+ channels modulate human placental trophoblast syncytialization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Pleiotropic actions of forskolin result in phosphatidylserine exposure in primary trophoblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Physiological roles of Rho and Rho effectors in mammals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Human placental trophoblasts confer viral resistance to recipient cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

FilGAP and its close relatives: a mediator of Rho-Rac antagonism that regulates cell morphology and migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Reciprocal regulation of PKA and Rac signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Membrane-type matrix metalloproteinase 1 regulates trophoblast functions and is reduced in fetal growth restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Involvement of membrane GRP78 in trophoblastic cell fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

RhoE is regulated by cyclic AMP and promotes fusion of human BeWo choriocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

A novel cyclic AMP/Epac1/CaMKI signaling cascade promotes GCM1 desumoylation and placental cell fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Placental and trophoblastic in vitro models to study preventive and therapeutic agents for preeclampsia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Calponin 3 Regulates Actin Cytoskeleton Rearrangement in Trophoblastic Cell Fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Trophoblast invasion: assessment of cellular models using gene expression signatures.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

MT1-MMP is required for myeloid cell fusion via regulation of Rac1 signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

GTP-binding proteins of the Rho/Rac family: regulation, effectors and functions in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Stimulation of GCMa and syncytin via cAMP mediated PKA signaling in human trophoblastic cells under normoxic and hypoxic conditions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Rational design and characterization of a Rac GTPase-specific small molecule inhibitor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

A two-colour fluorescence assay for the measurement of syncytial fusion between trophoblast-derived cell lines.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Rocks: multifunctional kinases in cell behaviour

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

GCMa regulates the syncytin-mediated trophoblastic fusion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Pharmacological properties of Y-27632, a specific inhibitor of rho-associated kinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Syncytin is a captive retroviral envelope protein involved in human placental morphogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

The cellular mechanism by which the human endogenous retrovirus ERV-3 env gene affects proliferation and differentiation in a human placental trophoblast model, BeWo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

8-Bromo-3',5'-adenosine monophosphate stimulates the endocrine activity of human cytotrophoblasts in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5438149

21 June 2018

Purification, Characterization, andin vitroDifferentiation of Cytotrophoblasts from Human Term Placentae*

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

Molecular pathway and cell state responsible for dissociation-induced apoptosis in human pluripotent stem cells.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

Enhancement on primate corneal endothelial cell survival in vitro by a ROCK inhibitor.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

Preparation and functional characterization of villous cytotrophoblasts free of syncytial fragments

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

Involvement of cyclin D and p27 in cell proliferation mediated by ROCK inhibitors Y-27632 and Y-39983 during corneal endothelium wound healing.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

The human villous cytotrophoblast: Interactions with extracellular matrix proteins, endocrine function, and cytoplasmic differentiation in the absence of syncytium formation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

ROCK and mDia1 antagonize in Rho-dependent Rac activation in Swiss 3T3 fibroblasts

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

ERK1/2 and p38 regulate trophoblasts differentiation in human term placenta.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

Modulation of PC12 cell viability by forskolin-induced cyclic AMP levels through ERK and JNK pathways: an implication for L-DOPA-induced cytotoxicity in nigrostriatal dopamine neurons

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

Rho-associated protein kinase II (rock II) expression in normal and preeclamptic human placentas

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0177994

21 January 2018

ZO-1 is involved in trophoblastic cell differentiation in human placenta

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

E-cadherin expression during the differentiation of human trophoblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Epidermal growth factor induces differentiation and secretion of human chorionic gonadotropin and placental lactogen in normal human placenta.

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell Culture Models of Human Trophoblast: Primary Culture of Trophoblast—A Workshop Report

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cyclic AMP-dependent protein kinases and human trophoblast cell differentiation in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and culture of term human trophoblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro cultured human term cytotrophoblast: a model for normal primary epithelial cells demonstrating a spontaneous differentiation programme that requires EGF for extensive development of syncytium

1 reference

https://pubmed.ncbi.nlm.nih.gov/28542501

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0177994

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28542501%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

2017PLoSO..1277994M

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1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28542501%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:28542501%20AND%20SRC:MED&resulttype=core&format=json

21 March 2020

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