(Q33709784)

28 July 2017

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title

The metabolism of antihistamines and drug interactions: the role of cytochrome P450 enzymes (English)

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28 July 2017

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Renwick AG

1

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28 July 2017

publication date

1 July 1999

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Clinical & Experimental Allergy

28 July 2017

published in

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28 July 2017

volume

29 Suppl 3

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28 July 2017

page(s)

116-124

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Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction

28 July 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

CYP3A gene expression in human gut epithelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Identification of human liver cytochrome P450 enzymes that metabolize the nonsedating antihistamine loratadine. Formation of descarboethoxyloratadine by CYP3A4 and CYP2D6.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

A population study of the pharmacokinetics of felodipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Torsade de pointes induced by terfenadine in a patient with long QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

The role of ketoconazole in the QTc interval prolonging effects of H1-antihistamines in a guinea-pig model of arrhythmogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Torsade de pointes with an antihistamine metabolite: potassium channel blockade with desmethylastemizole

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

A comparative pharmacokinetic-pharmacodynamic study of the electrocardiographic effects of epinastine and terfenadine in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Cardiac actions of antihistamines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Influence of itraconazole on the pharmacokinetics and electrocardiographic effects of astemizole

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Pharmacokinetic drug interactions with antimicrobial agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Pharmacokinetic interactions of the macrolide antibiotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Azithromycin and terfenadine: lack of drug interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Loratadine administered concomitantly with erythromycin: pharmacokinetic and electrocardiographic evaluations

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Cimetidine does not influence the metabolism of the H1-receptor antagonist ebastine to its active metabolite carebastine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Interaction of citrus juices with felodipine and nifedipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Quercetin, an in vitro inhibitor of CYP3A, does not contribute to the interaction between nifedipine and grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Inhibitory effect of grapefruit juice and its bitter principal, naringenin, on CYP1A2 dependent metabolism of caffeine in man.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Factors affecting the absolute bioavailability of nifedipine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Newer antidepressants and the cytochrome P450 system

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Evaluation of drug interactions in intact hepatocytes: Inhibitors of terfenadine metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

Pharmacokinetic Optimisation of Histamine H1-Receptor Antagonist Therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2222.1999.0290S3116.X

10.1046/J.1365-2222.1999.0290S3116.X

21 January 2018

Identifiers

DOI

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28 July 2017

1 reference