(Q33904220)

29 July 2017

Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery (English)

1 reference

29 July 2017

1 reference

1 reference

Hebert MF

1

1 reference

PubMed ID

10837558

29 July 2017

language of work or name

English

0 references

publication date

1 September 1997

1 reference

Advanced Drug Delivery Reviews

29 July 2017

1 reference

29 July 2017

27

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29 July 2017

201-214

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29 July 2017

2-3

1 reference

Differentiation of absorption and first-pass gut and hepatic metabolism in humans: studies with cyclosporine

29 July 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Bioavailability of cyclosporine with concomitant rifampin administration is markedly less than predicted by hepatic enzyme induction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Variability in nifedipine pharmacokinetics and dynamics: a new oxidation polymorphism in man

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Lack of bimodality in nifedipine plasma kinetics in a large population of healthy subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Identification of glucocorticoid-inducible cytochromes P-450 in the intestinal mucosa of rats and man

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Identification of an inducible form of cytochrome P-450 in human liver

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Erythromycin breath test as an assay of glucocorticoid-inducible liver cytochromes P-450. Studies in rats and patients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

The effects of ketoconazole on the intestinal metabolism and bioavailability of cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporin-erythromycin interaction in renal transplant patients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

The erythromycin breath test as a predictor of cyclosporine blood levels.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

First-pass metabolism of cyclosporin by the gut

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporin metabolism by human gastrointestinal mucosal microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Isolation of human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cell Surface P-Glycoprotein Associated with Multidrug Resistance in Mammalian Cell Lines

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Detection of P-glycoprotein with four monoclonal antibodies in normal and tumor tissues.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Role of intestinal P-glycoprotein (mdr1) in interpatient variation in the oral bioavailability of cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Reduced cyclosporin accumulation in multidrug-resistant cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Concomitant administration of cyclosporin and ketoconazole in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Synthesis and activity against multidrug resistance in Chinese hamster ovary cells of new acridone-4-carboxamides

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Reconstitution of drug transport by purified P-glycoprotein

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Reversal agent inhibition of the multidrug resistance pump in human leukemic lymphoblasts.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Identification of P450 enzymes involved in metabolism of verapamil in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Agents which reverse multidrug-resistance are inhibitors of [3H]vinblastine transport by isolated vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Verapamil decreases P-glycoprotein expression in multidrug-resistant human leukemic cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Expression and function of multidrug resistance P-glycoprotein in a cultured natural killer cell-rich population revealed by MRK16 monoclonal antibody and AHC-52

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Decrease in a constitutive form of cytochrome P-450 by macrolide antibiotics

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Identification of the cytochrome P-450 induced by macrolide antibiotics in rat liver as the glucocorticoid responsive cytochrome P-450p

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

In vivo induction of liver P-glycoprotein expression by xenobiotics in monkeys.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Effects of imidazole derivatives on cytochromes P450 from human hepatocytes in primary culture

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Reversal effect of itraconazole on adriamycin and etoposide resistance in human leukemia cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

In vivo induction of cytochrome P450 CYP3A expression in rat leukocytes using various inducers

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Naringin and naringenin are not the primary CYP3A inhibitors in grapefruit juice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Rifampicin enhances anti-cancer drug accumulation and activity in multidrug-resistant cells

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Distinct effects of phenobarbital and its N-methylated derivative on liver cytochrome P450 induction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Purification and characterization of an anticonvulsant-induced human cytochrome P-450 catalysing cyclosporin metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporine-amiodarone interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Amiodarone-cyclosporine interaction in cardiac transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

CYCLOSPORIN INTERACTION WITH KETOCONAZOLE AND MELPHALAN

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Ketoconazole, cyclosporin metabolism, and renal transplantation

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporine dose reduction by ketoconazole administration in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Time course of cyclosporin/itraconazole interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction of cyclosporin and itraconazole

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporine and itraconazole interaction in heart and lung transplant recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Fluconazole-cyclosporine interaction: a dose-dependent effect?

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction of fluconazole and cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

INTERACTION OF FLUCONAZOLE WITH CYCLOSPORIN

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Diltiazem and economic use of cyclosporin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Influence of diltiazem on cyclosporin clearance

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporin-diltiazem interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Effect of calcium-channel blockers on cyclosporine clearance and use in renal transplant patients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Verapamil inhibits cyclosporin metabolism

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Nicardipine increases cyclosporin blood levels

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

High dose methylprednisolone increases plasma cyclosporin levels in renal transplant recipients

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Erythromycin and cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Erythromycin-cyclosporin interaction

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction between cyclosporin and erythromycin in a kidney transplant patient

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Possible interaction between cyclosporine and erythromycin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction between erythromycin and cyclosporine in a kidney and pancreas allograft recipient

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Exacerbation of cyclosporine toxicity by concomitant administration of erythromycin.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Multiple drug interactions with cyclosporine in a heart transplant patient

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Disposition of intravenous and oral cyclosporine after administration with grapefruit juice

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

The effect of oral metoclopramide on the absorption of cyclosporine

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

The effect of water-soluble vitamin E on cyclosporine pharmacokinetics in healthy volunteers

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

ORAL CONTRACEPTIVE INTERACTION WITH CYCLOSPORIN

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Cyclosporin interaction with danazol and norethisterone

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Lack of effect of the calcium antagonist isradipine on cyclosporine pharmacokinetics in renal transplant patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Calcium channel antagonists and cyclosporine metabolism: in vitro studies with human liver microsomes

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction between cyclosporin A and phenobarbitone

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Evaluation of cyclosporin-phenytoin interaction with observations on cyclosporin metabolites

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Acute rejection and massive cyclosporine requirements in heart transplant recipients treated with rifampin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Low cyclosporin A blood levels and acute graft rejection in a renal transplant recipient during rifampin treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Effect of rifampicin on cyclosporin A blood levels in a renal transplant recipient

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Rapid metabolism of cyclosporin and prednisone in kidney transplant patient receiving tuberculostatic treatment

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Evaluation of the drug interaction between intravenous high-dose fluconazole and cyclosporine or tacrolimus in bone marrow transplant patients.

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction between FK506 and clotrimazole in a liver transplant recipient

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

FK 506 interaction with danazol

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction between FK506 and erythromycin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

Interaction between tacrolimus and erythromycin

1 reference

https://api.crossref.org/works/10.1016%2FS0169-409X%2897%2900043-4

7 January 2021

10.1016/S0169-409X(97)00043-4

Identifiers

DOI

1 reference

29 July 2017

1 reference

PubMed ID

10837558