(Q33710045)

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Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival [...]

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20920304%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

Scoring of senescence signalling in multiple human tumour gene expression datasets, identification of a correlation between senescence score and drug toxicity in the NCI60 panel and a pro-inflammatory signature correlating with survival advantage in peritoneal mesothelioma (English)

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15 February 2020

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Alan E Bilsland

2

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15 February 2020

Claire J Cairney

3

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15 February 2020

Nadia Zaffaroni

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15 February 2020

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15 February 2020

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15 February 2020

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Kyle Lafferty-Whyte

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15 February 2020

Lorna Hanley

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15 February 2020

Nigel B Jamieson

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15 February 2020

Sharon Burns

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15 February 2020

Jon Roffey

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15 February 2020

Susan M Boyd

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15 February 2020

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1 October 2010

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15 February 2020

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15 February 2020

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15 February 2020

532

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15 February 2020

https://scigraph.springernature.com/pub.10.1186/1471-2164-11-532

0 references

TCEAL7 inhibition of c-Myc activity in alternative lengthening of telomeres regulates hTERT expression

1 reference

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21 June 2018

Telomerase upregulation is a postcrisis event during senescence bypass and immortalization of two Nijmegen breakage syndrome T cell cultures

1 reference

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21 June 2018

New specific molecular targets for radio-chemotherapy of rectal cancer

1 reference

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21 June 2018

Upregulation of monocyte/macrophage HGFIN (Gpnmb/Osteoactivin) expression in end-stage renal disease

1 reference

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21 June 2018

A gene expression signature classifying telomerase and ALT immortalization reveals an hTERT regulatory network and suggests a mesenchymal stem cell origin for ALT.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Dynamic telomerase gene suppression via network effects of GSK3 inhibition

1 reference

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21 June 2018

Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Analysis of gene expression data using BRB-ArrayTools.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Autophagy mediates the mitotic senescence transition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

SASP reflects senescence.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Senescence-messaging secretome: SMS-ing cellular stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Proteins induced by telomere dysfunction and DNA damage represent biomarkers of human aging and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

How shelterin protects mammalian telomeres

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Accelerated senescence: an emerging role in tumor cell response to chemotherapy and radiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Oncogene-induced senescence relayed by an interleukin-dependent inflammatory network

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Replicative senescence of mesenchymal stem cells: a continuous and organized process

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Aging by epigenetics--a consequence of chromatin damage?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

High level of telomerase RNA gene expression is associated with chromatin modification, the ALT phenotype and poor prognosis in liposarcoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Osteoactivin is a novel osteoclastic protein and plays a key role in osteoclast differentiation and activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Cellular senescence in vivo: a barrier to tumorigenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

How to make a melanoma: what do we know of the primary clonal events?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Cellular senescence: when bad things happen to good cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Mitochondrial dysfunction accounts for the stochastic heterogeneity in telomere-dependent senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Cellular senescence and chromatin organisation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Molecular dissection of formation of senescence-associated heterochromatin foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

An accelerated senescence response to radiation in wild-type p53 glioblastoma multiforme cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Oncogene-Induced Senescence: Putting the Brakes on Tumor Development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Structural stability and chromosome-specific telomere length is governed by cis-acting determinants in humans.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Molecular similarity and diversity in chemoinformatics: from theory to applications.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

p53-Dependent accelerated senescence induced by ionizing radiation in breast tumour cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Whole-genome expression profiling of the melanoma progression pathway reveals marked molecular differences between nevi/melanoma in situ and advanced-stage melanomas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Frequent alteration of p16(INK4a)/p14(ARF) and p53 pathways in the round cell component of myxoid/round cell liposarcoma: p53 gene alterations and reduced p14(ARF) expression both correlate with poor prognosis.

1 reference

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21 June 2018

Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers.

1 reference

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21 June 2018

Formation of MacroH2A-containing senescence-associated heterochromatin foci and senescence driven by ASF1a and HIRA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Prediction of toxicant-specific gene expression signatures after chemotherapeutic treatment of breast cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Reversal of human cellular senescence: roles of the p53 and p16 pathways

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3091681

21 June 2018

Oxidative stress shortens telomeres

1 reference

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21 June 2018

Induction of cell death by radiotherapy

1 reference

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21 June 2018

A gene expression database for the molecular pharmacology of cancer

1 reference

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21 June 2018

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

1 reference

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21 June 2018

Tumor stroma-derived TGF-beta limits myc-driven lymphomagenesis via Suv39h1-dependent senescence.

1 reference

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30 October 2018

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1 reference

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30 October 2018

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1 reference

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12 December 2020

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1 reference

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12 December 2020

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inferred from PubMed ID database lookup

A senescence program controlled by p53 and p16INK4a contributes to the outcome of cancer therapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20920304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of global DNA methylation profiles in replicative versus premature senescence

1 reference

https://pubmed.ncbi.nlm.nih.gov/20920304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P16 loss and mitotic activity predict poor survival in patients with peritoneal malignant mesothelioma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20920304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple Mechanisms of Telomere Maintenance Exist and Differentially Affect Clinical Outcome in Diffuse Malignant Peritoneal Mesothelioma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20920304

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1471-2164-11-532

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Europe PubMed Central

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15 February 2020

Dimensions Publication ID

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https://scigraph.springernature.com/pub.10.1186/1471-2164-11-532

9 September 2019

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20920304%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

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15 February 2020

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