(Q33716194)

28 July 2017

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title

Pharmacology of antisense oligonucleotide inhibitors of protein expression (English)

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28 July 2017

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Cooper SR

1

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28 July 2017

Taylor JK

series ordinal

2

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28 July 2017

Miraglia LJ

series ordinal

3

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28 July 2017

Dean NM

series ordinal

4

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28 July 2017

publication date

1 May 1999

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Pharmacology & Therapeutics

28 July 2017

published in

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28 July 2017

volume

82

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28 July 2017

issue

2-3

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28 July 2017

page(s)

427-435

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2'-O-(2-Methoxy)ethyl-modified anti-intercellular adhesion molecule 1 (ICAM-1) oligonucleotides selectively increase the ICAM-1 mRNA level and inhibit formation of the ICAM-1 translation initiation complex in human umbilical vein endothelial cells.

28 July 2017

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Electroporation enhances c-myc antisense oligodeoxynucleotide efficacy

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Improved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

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7 January 2021

The JUN kinase/stress-activated protein kinase pathway is required for epidermal growth factor stimulation of growth of human A549 lung carcinoma cells.

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A versatile vector for gene and oligonucleotide transfer into cells in culture and in vivo: polyethylenimine

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7 January 2021

Control of complexity constraints on combinatorial screening for preferred oligonucleotide hybridization sites on structured RNA.

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7 January 2021

Peptide nucleic acids and their potential applications in biotechnology.

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7 January 2021

Inhibition of leukemia cell proliferation by receptor-mediated uptake of c-myb antisense oligodeoxynucleotides

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7 January 2021

Altered mRNA splicing and inhibition of human E-selectin expression by an antisense oligonucleotide in human umbilical vein endothelial cells

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7 January 2021

Progress in antisense oligonucleotide therapeutics

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7 January 2021

Characterization of fully 2'-modified oligoribonucleotide hetero- and homoduplex hybridization and nuclease sensitivity

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7 January 2021

Antisense oligonucleotides as inhibitors of genes that regulate AP-1: pharmacology and clinical development

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7 January 2021

Cooperation of pre-mRNA sequence elements in splice site selection

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7 January 2021

Site specific enzymatic cleavage of RNA

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7 January 2021

Detection of ribonuclease H-generated mRNA fragments in human leukemia cells following reversible membrane permeabilization in the presence of antisense oligodeoxynucleotides.

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7 January 2021

Selecting optimal oligonucleotide composition for maximal antisense effect following streptolysin O-mediated delivery into human leukaemia cells

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7 January 2021

Potent antisense oligonucleotides to the human multidrug resistance-1 mRNA are rationally selected by mapping RNA-accessible sites with oligonucleotide libraries

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7 January 2021

Peptide nucleic acids (PNA): synthesis, properties and potential applications

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7 January 2021

Sequence-dependent hydrolysis of RNA using modified oligonucleotide splints and RNase H

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7 January 2021

Uniformly modified 2'-deoxy-2'-fluoro phosphorothioate oligonucleotides as nuclease-resistant antisense compounds with high affinity and specificity for RNA targets

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7 January 2021

Efficient transfer of genetic material into mammalian cells using Starburst polyamidoamine dendrimers

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7 January 2021

Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells.

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7 January 2021

Protein kinase C-zeta mediates angiotensin II activation of ERK1/2 in vascular smooth muscle cells

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7 January 2021

Implication of RNA structure on antisense oligonucleotide hybridization kinetics

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7 January 2021

Phosphorothioate oligodeoxyribonucleotides dissociate from cationic lipids before entering the nucleus

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7 January 2021

Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modifications

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7 January 2021

Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression

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7 January 2021

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

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7 January 2021

Nuclease resistance and antisense activity of modified oligonucleotides targeted to Ha-ras

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7 January 2021

Specific and stable intron-factor interactions are established early during in vitro pre-mRNA splicing

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7 January 2021

Specific binding of lac repressor to linear versus circular polyoperator molecules.

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7 January 2021

Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides

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7 January 2021

Arrays of complementary oligonucleotides for analysing the hybridisation behaviour of nucleic acids

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7 January 2021

Problems in interpretation of data derived from in vitro and in vivo use of antisense oligodeoxynucleotides

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7 January 2021

Reduction of expression of the multidrug resistance protein (MRP) in human tumor cells by antisense phosphorothioate oligonucleotides

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7 January 2021

Predicting antisense oligonucleotide inhibitory efficacy: a computational approach using histograms and thermodynamic indices

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7 January 2021

An in vitro messenger RNA binding assay as a tool for identifying hybridization-competent antisense oligonucleotides

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7 January 2021

PKC-epsilon is required for mechano-sensitive activation of ERK1/2 in endothelial cells

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7 January 2021

Tetranucleotide GGGA motif in primary RNA transcripts. Novel target site for antisense design

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7 January 2021

Molecular cloning and expression of cDNA for human RNase H.

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7 January 2021

Inhibition of Rous sarcoma virus replication and cell transformation by a specific oligodeoxynucleotide

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7 January 2021

Serine/threonine protein phosphatase type 5 acts upstream of p53 to regulate the induction of p21(WAF1/Cip1) and mediate growth arrest

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7 January 2021

10.1016/S0163-7258(99)00002-9

Identifiers

DOI

1 reference

28 July 2017

1 reference