(Q33721800)

28 July 2017

title

The mismatch repair system modulates curcumin sensitivity through induction of DNA strand breaks and activation of G2-M checkpoint (English)

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28 July 2017

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1 reference

Zhihua Jiang

1

1 reference

28 July 2017

ShunQian Jin

2

1 reference

28 July 2017

Jack C Yalowich

3

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28 July 2017

Kevin D Brown

4

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28 July 2017

Baskaran Rajasekaran

5

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28 July 2017

publication date

9 February 2010

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Molecular Cancer Therapeutics

28 July 2017

published in

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28 July 2017

volume

9

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28 July 2017

issue

3

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28 July 2017

page(s)

558-568

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Curcumin modulates the radiosensitivity of colorectal cancer cells by suppressing constitutive and inducible NF-kappaB activity

28 July 2017

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MLH1- and ATM-dependent MAPK signaling is activated through c-Abl in response to the alkylator N-methyl-N'-nitro-N'-nitrosoguanidine

21 June 2018

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Evidence that curcumin suppresses the growth of malignant gliomas in vitro and in vivo through induction of autophagy: role of Akt and extracellular signal-regulated kinase signaling pathways

21 June 2018

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Resistance to apoptosis of HCW-2 cells can be overcome by curcumin- or vincristine-induced mitotic catastrophe

21 June 2018

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ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts

21 June 2018

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Oxidative stress induces a prolonged but reversible arrest in p53-null cancer cells, involving a Chk1-dependent G2 checkpoint.

21 June 2018

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21 June 2018

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21 June 2018

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Induction of apoptosis by curcumin and its implications for cancer therapy

21 June 2018

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High doses of SN1 type methylating agents activate DNA damage signaling cascades that are largely independent of mismatch repair.

21 June 2018

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Methylator-induced, mismatch repair-dependent G2 arrest is activated through Chk1 and Chk2

21 June 2018

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Chromosomal passengers: the four-dimensional regulation of mitotic events

21 June 2018

1 reference

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Mismatch repair and DNA damage signalling

21 June 2018

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Inhibition of nuclear factor-kappaB and nitric oxide by curcumin induces G2/M cell cycle arrest and apoptosis in human melanoma cells

21 June 2018

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Mismatch repair-dependent G2 checkpoint induced by low doses of SN1 type methylating agents requires the ATR kinase

21 June 2018

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Paclitaxel-induced apoptosis may occur without a prior G2/M-phase arrest.

21 June 2018

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MSH2 and ATR form a signaling module and regulate two branches of the damage response to DNA methylation

21 June 2018

1 reference

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Chk1 and Chk2 kinases in checkpoint control and cancer

21 June 2018

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Chemotherapeutic potential of curcumin for colorectal cancer

21 June 2018

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Mismatch repair and the hereditary non-polyposis colorectal cancer syndrome (HNPCC)

21 June 2018

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ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1

21 June 2018

1 reference

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The role of mismatch repair in DNA damage-induced apoptosis.

21 June 2018

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The Chk1 protein kinase and the Cdc25C regulatory pathways are targets of the anticancer agent UCN-01

21 June 2018

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Eukaryotic DNA mismatch repair

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Linkage of ATM to cell cycle regulation by the Chk2 protein kinase

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Biallelic inactivation of hMLH1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers.

21 June 2018

1 reference

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Repair of oxidative damage to nuclear and mitochondrial DNA in mammalian cells

21 June 2018

1 reference

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Correction of hypermutability, N-methyl-N'-nitro-N-nitrosoguanidine resistance, and defective DNA mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Curcumin induces apoptosis in immortalized NIH 3T3 and malignant cancer cell lines

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Loss of DNA mismatch repair in acquired resistance to cisplatin

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Human chromosome 3 corrects mismatch repair deficiency and microsatellite instability and reduces N-methyl-N'-nitro-N-nitrosoguanidine tolerance in colon tumor cells with homozygous hMLH1 mutation

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Induction of G2/M arrest and inhibition of cyclooxygenase-2 activity by curcumin in human bladder cancer T24 cells.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Curcumin induces human HT-29 colon adenocarcinoma cell apoptosis by activating p53 and regulating apoptosis-related protein expression

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Consumption of the putative chemopreventive agent curcumin by cancer patients: assessment of curcumin levels in the colorectum and their pharmacodynamic consequences

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Spindle checkpoint function is required for mitotic catastrophe induced by DNA-damaging agents

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Effect of H(2)O(2) on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Curcumin disrupts mitotic spindle structure and induces micronucleation in MCF-7 breast cancer cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Microtubule damaging agents induce apoptosis in HL 60 cells and G2/M cell cycle arrest in HT 29 cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Curcumin Affects Components of the Chromosomal Passenger Complex and Induces Mitotic Catastrophe in Apoptosis-Resistant Bcr-Abl-Expressing Cells

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2837109

Curcumin mediated apoptosis in AK-5 tumor cells involves the production of reactive oxygen intermediates

30 October 2018

1 reference

12 December 2020

MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae

1 reference

12 December 2020

c-Abl kinase regulates curcumin-induced cell death through activation of c-Jun N-terminal kinase

1 reference

12 December 2020

Inhibition of cyclo-oxygenase 2 expression in colon cells by the chemopreventive agent curcumin involves inhibition of NF-kappaB activation via the NIK/IKK signalling complex

1 reference

12 December 2020

10.1158/1535-7163.MCT-09-0627

Identifiers

DOI

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28 July 2017

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28 July 2017

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