(Q33723268)

28 July 2017

title

The membrane-bound structure and topology of a human α-defensin indicate a dimer pore mechanism for membrane disruption (English)

1 reference

28 July 2017

2

Wuyuan Lu

1 reference

28 July 2017

Yuan Zhang

1

1 reference

28 July 2017

Mei Hong

series ordinal

3

1 reference

28 July 2017

language of work or name

English

0 references

publication date

26 October 2010

1 reference

28 July 2017

1 reference

28 July 2017

volume

49

1 reference

28 July 2017

issue

45

1 reference

28 July 2017

page(s)

9770-9782

1 reference

Insight into invertebrate defensin mechanism of action: oyster defensins inhibit peptidoglycan biosynthesis by binding to lipid II.

28 July 2017

cites work

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Membrane-bound dynamic structure of an arginine-rich cell-penetrating peptide, the protein transduction domain of HIV TAT, from solid-state NMR.

14 July 2018

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Orientation, dynamics, and lipid interaction of an antimicrobial arylamide investigated by 19F and 31P solid-state NMR spectroscopy

14 July 2018

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Plectasin, a fungal defensin, targets the bacterial cell wall precursor Lipid II.

14 July 2018

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Human beta-defensin 3 inhibits cell wall biosynthesis in Staphylococci

14 July 2018

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Functional interaction of human neutrophil peptide-1 with the cell wall precursor lipid II.

14 July 2018

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Resonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMR

14 July 2018

1 reference

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Selective arginines are important for the antibacterial activity and host cell interaction of human alpha-defensin 5

14 July 2018

1 reference

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Structure and mechanism of beta-hairpin antimicrobial peptides in lipid bilayers from solid-state NMR spectroscopy.

14 July 2018

1 reference

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Roles of arginine and lysine residues in the translocation of a cell-penetrating peptide from (13)C, (31)P, and (19)F solid-state NMR.

14 July 2018

1 reference

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Effects of arginine density on the membrane-bound structure of a cationic antimicrobial peptide from solid-state NMR.

14 July 2018

1 reference

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Molecular determinants for the interaction of human neutrophil alpha defensin 1 with its propeptide

14 July 2018

1 reference

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Phosphate-mediated arginine insertion into lipid membranes and pore formation by a cationic membrane peptide from solid-state NMR.

14 July 2018

1 reference

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Structure, topology, and dynamics of membrane peptides and proteins from solid-state NMR spectroscopy

14 July 2018

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Human defensin alpha-1 causes Trypanosoma cruzi membrane pore formation and induces DNA fragmentation, which leads to trypanosome destruction

14 July 2018

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Toward understanding the cationicity of defensins. Arg and Lys versus their noncoded analogs

14 July 2018

1 reference

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Orientation Determination of Membrane-Disruptive Proteins Using Powder Samples and Rotational Diffusion: A Simple Solid-State NMR Approach

14 July 2018

1 reference

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Oligomeric structure, dynamics, and orientation of membrane proteins from solid-state NMR.

14 July 2018

1 reference

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Crystal structures of human alpha-defensins HNP4, HD5, and HD6

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Membrane-dependent oligomeric structure and pore formation of a beta-hairpin antimicrobial peptide in lipid bilayers from solid-state NMR.

14 July 2018

1 reference

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Peptide-lipid interactions of the beta-hairpin antimicrobial peptide tachyplesin and its linear derivatives from solid-state NMR.

14 July 2018

1 reference

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Effects of the terminal charges in human neutrophil alpha-defensin 2 on its bactericidal and membrane activity

14 July 2018

1 reference

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Reconstruction of the conserved beta-bulge in mammalian defensins using D-amino acids.

14 July 2018

1 reference

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Large structure rearrangement of colicin ia channel domain after membrane binding from 2D 13C spin diffusion NMR.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Noncovalent binding between guanidinium and anionic groups: focus on biological- and synthetic-based arginine/guanidinium interactions with phosph[on]ate and sulf[on]ate residues

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Concentration-dependent realignment of the antimicrobial peptide PGLa in lipid membranes observed by solid-state 19F-NMR.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Antibacterial activity and specificity of the six human {alpha}-defensins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Investigations of polypeptide rotational diffusion in aligned membranes by 2H and 15N solid-state NMR spectroscopy

14 July 2018

1 reference

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Synthesis and characterization of human alpha-defensins 4-6.

14 July 2018

1 reference

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Defensins: antimicrobial peptides of innate immunity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

De novo determination of peptide structure with solid-state magic-angle spinning NMR spectroscopy.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Conformational changes of colicin Ia channel-forming domain upon membrane binding: a solid-state NMR study

14 July 2018

1 reference

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Probability-based protein secondary structure identification using combined NMR chemical-shift data

14 July 2018

1 reference

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The structure of human beta-defensin-2 shows evidence of higher order oligomerization

14 July 2018

1 reference

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The penultimate rotamer library

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Antimicrobial peptides in mammalian and insect host defence

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Critical role of lipid composition in membrane permeabilization by rabbit neutrophil defensins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Defensins: antimicrobial and cytotoxic peptides of mammalian cells

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Defensin-6 mRNA in human Paneth cells: implications for antimicrobial peptides in host defense of the human bowel

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Defensins promote fusion and lysis of negatively charged membranes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Primary structures of three human neutrophil defensins

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Defensins. Natural peptide antibiotics of human neutrophils

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Interaction of human defensins with Escherichia coli. Mechanism of bactericidal activity

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Antibiotic proteins of human polymorphonuclear leukocytes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Crystal structure of defensin HNP-3, an amphiphilic dimer: mechanisms of membrane permeabilization

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Antimicrobial defensin peptides form voltage-dependent ion-permeable channels in planar lipid bilayer membranes

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Paneth cells of the human small intestine express an antimicrobial peptide gene

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

3D (13)C-(13)C-(13)C correlation NMR for de novo distance determination of solid proteins and application to a human alpha-defensin.

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Effects of guanidinium-phosphate hydrogen bonding on the membrane-bound structure and activity of an arginine-rich membrane peptide from solid-state NMR spectroscopy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Side-chain conformation of the M2 transmembrane peptide proton channel of influenza a virus from 19F solid-state NMR.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Determining the orientation of uniaxially rotating membrane proteins using unoriented samples: a 2H, 13C, AND 15N solid-state NMR investigation of the dynamics and orientation of a transmembrane helical bundle.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Expression and purification of recombinant human alpha-defensins in Escherichia coli.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Determination of the oligomeric number and intermolecular distances of membrane protein assemblies by anisotropic 1H-driven spin diffusion NMR spectroscopy.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Determination of peptide oligomerization in lipid bilayers using 19F spin diffusion NMR.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

4-fluorophenylglycine as a label for 19F NMR structure analysis of membrane-associated peptides

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Productive folding of human neutrophil alpha-defensins in vitro without the pro-peptide

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Membrane protein topology probed by (1)H spin diffusion from lipids using solid-state NMR spectroscopy

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Solid-state NMR investigation of the dynamics of the soluble and membrane-bound colicin Ia channel-forming domain.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Resonance assignment of 13C/15N labeled solid proteins by two- and three-dimensional magic-angle-spinning NMR

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2992833

Action of antimicrobial peptides: two-state model

30 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20961099

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

NMR structural analysis of a membrane protein: bacteriorhodopsin peptide backbone orientation and motion

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20961099

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of lipid II in membrane binding of and pore formation by nisin analyzed by two combined biosensor techniques

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20961099

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1021/BI101512J

1 reference

28 July 2017

1 reference

28 July 2017

1 reference